Book Hotels in South Sanford, ME
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Top South Sanford hotels

Hampton Inn & Suites Portsmouth Downtown
23 Portwalk Pl Portsmouth NH
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $133 total per night from May 25 to May 26
$133 total
May 25 - May 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. ...
This is the second time I’ve stayed there and it’s in a great location and the staff is friendly
Reviewed on May 1, 2026

Cliff House Maine
591 Shore Road Cape Neddick ME
$547 nightly
The price is $596 total per night from May 11 to May 12
$596 total
May 11 - May 12
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free resort. Traveling on business? Take advantage of the business center, ...
all was great. my favorite place!
Reviewed on Apr 29, 2026

Anchorage by the Sea
125 Shore Road Ogunquit ME
$202 nightly
The price is $220 total per night from May 3 to May 4
$220 total
May 3 - May 4
Total with taxes and fees
This smoke-free hotel features 2 hot tubs, an indoor pool, and a restaurant. Traveling on business? Take advantage of the free WiFi in public areas and onsite ...
Beautiful location and views. Easy access to the Marginal Way and Perkins Cove. Friendly staff and clean rooms.
Reviewed on Apr 25, 2026

Holiday Inn Express Wells-Ogunquit-Kennebunk by IHG
28 Mile Road Wells ME
Fully refundable
$114 nightly
The price is $124 total per night from May 10 to May 11
$124 total
May 10 - May 11
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
All ok
Reviewed on May 1, 2026

Anchorage Inn and Resort
265 Long Beach Avenue York Beach ME
$149 nightly
The price is $162 total per night from May 4 to May 5
$162 total
May 4 - May 5
Total with taxes and fees
This hotel features 2 indoor pools, an outdoor pool, and a restaurant. Enjoy the gym and perks like free self parking and free WiFi. Enjoy the hot tub and unwind ...
Room was clean, grounds nice, easy walk to beach. Walls very thin in main building, 2nd floor. Could hear every word of family next door, unfortunately. Otherwise it was ok just don’t plan on privacy.
Reviewed on May 1, 2026

Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel
200 Sterling Way Dover NH
Fully refundable
$113 nightly
The price is $123 total per night from May 25 to May 26
$123 total
May 25 - May 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
The room was very clean with great amenities and we definitely enjoyed the complimentary breakfast and popcorn. The staff was always friendly
Reviewed on Apr 30, 2026

The Colony Hotel
140 Ocean Ave Kennebunkport ME
$148 nightly
The price is $161 total per night from May 5 to May 6
$161 total
May 5 - May 6
Total with taxes and fees
This hotel features a restaurant, a seasonal outdoor pool, and a poolside bar. Traveling on business? Take advantage of the business center and free WiFi in ...
We stayed in late April when the main building was not yet open. The room was was very clean, heating and hot water worked perfectly. The onsite market is convenient for morning coffee and lounging. The staff have recommended some restaurants and a seafood market that turned out very good.
Reviewed on Apr 26, 2026

Hilton Garden Inn Portsmouth Downtown
100 High St Portsmouth NH
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $124 total per night from May 25 to May 26
$124 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
Staff was great, room and building clean. Only problem was the shower, very low water pressure, like a flower watering can.
Reviewed on Apr 27, 2026

Port Inn and Suites Portsmouth, an Ascend Collection Hotel
505 US Highway 1 Bypass Portsmouth NH
Fully refundable
$103 nightly
The price is $111 total per night from May 25 to May 26
$111 total
May 25 - May 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
just what we needed. close to route . small motel. all clean and warm . good breakfast.
Reviewed on Apr 23, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent South Sanford hotel reviews by fellow wanderers

Anchorage Inn and Resort
3 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Room was clean, grounds nice, easy walk to beach. Walls very thin in main building, 2nd floor. Could hear every word of family next door, unfortunately. Otherwise it was ok just don’t plan on privacy."
A verified traveler stayed at Anchorage Inn and Resort
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