Book Hotels in South Sanford, ME

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Top South Sanford hotels

Hampton Inn & Suites Portsmouth Downtown

Hampton Inn & Suites Portsmouth Downtown

3 out of 5
23 Portwalk Pl Portsmouth NH
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $133 total per night from Mar 22 to Mar 23
$133 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. ...
Staff was amazing and so helpful. They really went out of their way to help us.

Reviewed on Mar 12, 2026

Opens in a new windowHampton Inn & Suites Portsmouth Downtown
Cliff House Maine

Cliff House Maine

4.5 out of 5
591 Shore Road Cape Neddick ME
$557 nightly
The price is $607 total per night from Mar 26 to Mar 27
$607 total
Mar 26 - Mar 27
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free resort. Traveling on business? Take advantage of the business center, ...
Great hotel with super nice views!

Reviewed on Mar 1, 2026

Opens in a new windowCliff House Maine
The Hotel Portsmouth

The Hotel Portsmouth

3 out of 5
40 Court St. Portsmouth NH
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $132 total per night from Mar 23 to Mar 24
$132 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 4 ...
Very cute property

Reviewed on Mar 10, 2026

Opens in a new windowThe Hotel Portsmouth
Anchorage by the Sea

Anchorage by the Sea

3 out of 5
125 Shore Road Ogunquit ME
$183 nightly
The price is $199 total per night from Mar 15 to Mar 16
$199 total
Mar 15 - Mar 16
Total with taxes and fees
This smoke-free hotel features 2 hot tubs, an indoor pool, and a restaurant. Traveling on business? Take advantage of the free WiFi in public areas and onsite ...
We booked last minute while passing through town, we absolutely loved it and had a great experience. Def want to go back again in the warmer weather but gets pricey as the weather warms up

Reviewed on Mar 1, 2026

Opens in a new windowAnchorage by the Sea
Holiday Inn Express Wells-Ogunquit-Kennebunk by IHG

Holiday Inn Express Wells-Ogunquit-Kennebunk by IHG

3 out of 5
28 Mile Road Wells ME
Fully refundable
$94 nightly
The price is $102 total per night from Mar 29 to Mar 30
$102 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Room was clean but I got a handicapped room that I did not want. Shower was awful no pressure. Breakfast was awesome. Worth the stay for that

Reviewed on Mar 11, 2026

Opens in a new windowHoliday Inn Express Wells-Ogunquit-Kennebunk by IHG
Anchorage Inn and Resort

Anchorage Inn and Resort

3 out of 5
265 Long Beach Avenue York Beach ME
$89 nightly
The price is $97 total per night from Mar 20 to Mar 21
$97 total
Mar 20 - Mar 21
Total with taxes and fees
This hotel features 2 indoor pools, an outdoor pool, and a restaurant. Enjoy the gym and perks like free self parking and free WiFi. Enjoy the hot tub and unwind ...
Nice place, we will come back

Reviewed on Mar 12, 2026

Opens in a new windowAnchorage Inn and Resort
Sheraton Portsmouth Harborside Hotel

Sheraton Portsmouth Harborside Hotel

3.5 out of 5
250 Market St Portsmouth NH
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $160 total per night from Apr 5 to Apr 6
$160 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
I took my son and his friend for a belated birthday celebration. Our original trip was postponed due to a big snowstorm. When we arrived the staff was genuine and welcoming. At dinner the waitress was unbelievable. Kind, attentive AND when we said we were celebrating my son’s belated birthday and ...

Reviewed on Mar 10, 2026

Opens in a new windowSheraton Portsmouth Harborside Hotel
Hilton Garden Inn Portsmouth Downtown

Hilton Garden Inn Portsmouth Downtown

3 out of 5
100 High St Portsmouth NH
Fully refundable
$100 nightly
The price is $108 total per night from Mar 29 to Mar 30
$108 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
Amazing Staff! Ben was so kind and helpful! Awesome location, walk to everything. Everyone we encountered went above and beyond. We will be back!

Reviewed on Mar 9, 2026

Opens in a new windowHilton Garden Inn Portsmouth Downtown
Old Orchard Beach Inn

Old Orchard Beach Inn

2.5 out of 5
6 Portland Ave Old Orchard Beach ME
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $95 total per night from Mar 16 to Mar 17
$95 total
Mar 16 - Mar 17
Total with taxes and fees
A seasonal outdoor pool, free self parking, and wedding services are featured at this bed & breakfast. WiFi in public areas is free. A garden, a library, and ...
We stayed in a suite and it was old and dingy. It felt and smelled like a neglected grandma's house. The carpet was stained, the furniture was old, and the wallpaper was peeling. Beds had old springy mattresses. The utensils in the drawer were all very dirty. There was a sponge but no dish detergent ...

Reviewed on Feb 23, 2026

Opens in a new windowOld Orchard Beach Inn
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in South Sanford?
Family getaways are where treasured memories are made, but traveling with youngsters can be demanding. These kid-friendly South Sanford hotels come with perks designed to keep travelers of all ages comfortable and happy: You're well catered for at Huttopia Southern Maine. It comes with a swimming pool, a playground and a commitment to making families feel at home. Otherwise, spend your nights in South Sanford at Quality Inn. Make the most of complimentary breakfast, pet-friendly facilities and more here.
Where can I find cheap hotels in South Sanford?
At Travelocity you'll find really nice hotels in South Sanford at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near South Sanford rather than in South Sanford. We may find you even better rates, too.
How do I find the best South Sanford hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in South Sanford then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in South Sanford?
The cheapest hotel in South Sanford is $95. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in South Sanford?
There are 3,735 hotels in South Sanford on Travelocity.
What are the best hotels in South Sanford?
South Sanford has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in South Sanford for you!
When is the best time to visit South Sanford?
If you want the joy of a fun-filled trip in peak season, visit South Sanford during January, June and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as April, September and October.
When is the cheapest time to stay in South Sanford?
Based on historic data is usually the cheapest month to visit South Sanford. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in South Sanford?
There are multiple hotels in South Sanford that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to South Sanford. We have plenty of kid-friendly hotels in South Sanford to choose from on Travelocity!
Why book a hotel in South Sanford through Travelocity?
Because we have the top hotels in South Sanford! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in South Sanford on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent South Sanford hotel reviews by fellow wanderers

Residence Inn by Marriott Portsmouth Downtown/ Waterfront

Residence Inn by Marriott Portsmouth Downtown/ Waterfront

5 out of 5
Posted 10 hours ago
Travelocity Verified Review
"Stay here every year! Great staff and the location is perfect "
A verified traveler stayed at Residence Inn by Marriott Portsmouth Downtown/ Waterfront
Residence Inn by Marriott Portsmouth Downtown/ Waterfront

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