Book Hotels in South Roxana, IL
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Top South Roxana hotels

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $175 total per night from Mar 16 to Mar 17
$175 total
Mar 16 - Mar 17
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
Drury Inn’s are my favorite!
Reviewed on Mar 14, 2026

Drury Inn & Suites St. Louis Union Station
201 S 20th St St. Louis MO
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $162 total per night from Mar 22 to Mar 23
$162 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
We always stay at a Drury but this one was different, it was very loud , we had to park away from the building and had to pay 19 for parking. Will stay by the airport next time.
Reviewed on Mar 13, 2026

Live by Loews - St.Louis
799 Clark ave St. Louis MO
$149 nightly
The price is $177 total per night from Apr 5 to Apr 6
$177 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Within walking distance to the Dome!
Reviewed on Mar 14, 2026

Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from Mar 22 to Mar 23
$106 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
Clean, comfortable, safe place directly across the highway at airport. Very nice staff.
Reviewed on Mar 13, 2026

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $153 total per night from Apr 5 to Apr 6
$153 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
A fantastic stay. Great breakfast and excellent pool area. Would stay again
Reviewed on Mar 15, 2026

Pear Tree Inn St. Louis Near Union Station
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $124 total per night from Apr 5 to Apr 6
$124 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
This was a wonderful hotel to stay at while we explored the National Parks. We enjoyed the free evening snacks and drinks after a full day at Gateway Arch. Staff were very friendly. The pool was nice. Rooms very clean. Would definitely stop here again.
Reviewed on Mar 14, 2026

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $116 total per night from Mar 22 to Mar 23
$116 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Great breakfast!
Reviewed on Mar 14, 2026

Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
$169 nightly
The price is $199 total per night from Mar 23 to Mar 24
$199 total
Mar 23 - Mar 24
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
Very nice stay!!!
Reviewed on Mar 12, 2026

Hotel Indigo St Louis - Central West End by IHG
4630 Lindell St. Louis MO
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $146 total per night from Apr 5 to Apr 6
$146 total
Apr 5 - Apr 6
Total with taxes and fees
This Art Deco hotel features 4 restaurants, a bar/lounge, and a 24-hour gym. Business travelers can take advantage of the free WiFi in public areas. Self parking, ...
Cool
Reviewed on Mar 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent South Roxana hotel reviews by fellow wanderers

21C Museum Hotel St Louis
5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"A fantastic stay. Great breakfast and excellent pool area. Would stay again "
A verified traveler stayed at 21C Museum Hotel St Louis






