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Top Santa Rosa hotels
Central Hotel Panama Casco Viejo
Plaza de la Independencia Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
$195 nightly
The price is $215 total per night from Sep 19 to Sep 20
$215 total
Sep 19 - Sep 20
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in ...
"Muy satisfecha de las instalaciones, el ambiente, la zona, el desayuno y el personal, no tengo queja, solamente que en la noche, la música estaba fuerte, pero no duró mucho."
Reviewed on Aug 21, 2026
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall Panama City Panama
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $130 total per night from Sep 6 to Sep 7
$130 total
Sep 6 - Sep 7
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Buffet breakfast was switched up daily, room was spacious and clean, staff was very accommodating, great access to nearby mall and good location for shuttle pickup for excursions. Would definitely stay again and highly recommend."
Reviewed on Aug 21, 2026
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Sep 15 to Sep 16
$135 total
Sep 15 - Sep 16
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$145 nightly
The price is $159 total per night from Sep 4 to Sep 5
$159 total
Sep 4 - Sep 5
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Relax with a drink at the bar/lounge and enjoy free ...
Megapolis Hotel Panamá
Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $179 total per night from Sep 19 to Sep 20
$179 total
Sep 19 - Sep 20
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
Principe Hotel and Suites
Via Argentina Panama City Panama
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $62 total per night from Sep 17 to Sep 18
$62 total
Sep 17 - Sep 18
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Waldorf Astoria Panama
47th St. & Uruguay Street Panama City Panama
Fully refundableReserve now, pay when you stay
$266 nightly
The price is $292 total per night from Aug 30 to Aug 31
$292 total
Aug 30 - Aug 31
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...
Courtyard by Marriott Panama Metromall
Avenida Domingo Diaz via Tocumen San Miguelito Panama
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $108 total per night from Aug 22 to Aug 23
$108 total
Aug 22 - Aug 23
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Aloft by Marriott Panama
Via Israel & Calle 76 Panama City Panama
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $146 total per night from Aug 28 to Aug 29
$146 total
Aug 28 - Aug 29
Total with taxes and fees
A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Santa Rosa hotel reviews by fellow wanderers
Courtyard by Marriott Panama Multiplaza Mall
5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Buffet breakfast was switched up daily, room was spacious and clean, staff was very accommodating, great access to nearby mall and good location for shuttle pickup for excursions. Would definitely stay again and highly recommend."
A verified traveler stayed at Courtyard by Marriott Panama Multiplaza Mall
