Book Hotels in Santa Pera
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Santa Pera hotels
Hyatt Regency Panama City
Calle 52 and Ricardo Arias Panama City
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $178 total per night from May 2 to May 3
$178 total
May 2 - May 3
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public ...
Lobby, rooms and all facilities smelled amazing. Excellent conditions, well stocked, great service.
Reviewed on Apr 23, 2026
Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla Panama City Panama
$103 nightly
The price is $114 total per night from May 1 to May 2
$114 total
May 1 - May 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
We had a great stay. We stayed here for one night on our way to Bocas del Toro. It was close enough to both airports to make connections quick and easy. The hotel is nice and the staff was very friendly.
Reviewed on Apr 22, 2026
The Executive Hotel
Calle 52 Panama City Panama
Fully refundable
$81 nightly
The price is $89 total per night from May 5 to May 6
$89 total
May 5 - May 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
It was a central location close to everywhere.
Reviewed on Apr 23, 2026
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $151 total per night from May 5 to May 6
$151 total
May 5 - May 6
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
best breakfast in Panama
Reviewed on Apr 23, 2026
Principe Hotel and Suites
Via Argentina Panama City Panama
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $62 total per night from Apr 26 to Apr 27
$62 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
The property is centrally located within easy access of shopping and transportation. Good choice for travelers on a budget with a wide variety of places to eat.
Reviewed on Apr 22, 2026
Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $100 total per night from Apr 24 to Apr 25
$100 total
Apr 24 - Apr 25
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Traveling on business? Take advantage of the free ...
Breakfast was traditional Panamanian fare, mixed with the usual egg offerings, and the based goods were of good quality, also having salad available was a nice touch. The staff were multilingual, knowledgeable and friendly, and housekeeping did a great job. Overall the property is comfortable and ...
Reviewed on Apr 22, 2026
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$128 nightly
The price is $141 total per night from May 12 to May 13
$141 total
May 12 - May 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
Clean room
Reviewed on Apr 23, 2026
Radisson Hotel Panama Canal
Amador Avenue & Van Hook Street Panama City Panama
Fully refundable
$74 nightly
The price is $81 total per night from May 10 to May 11
$81 total
May 10 - May 11
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 2 outdoor pools, and a gym. Families will appreciate the children's pool and onsite laundry facilities. Unwind ...
The staff at the hotel was not accommodating at all. When advised on issues with the room, there was no response until we had to make a number of calls. The room was not cleaned properly causing us to have to call guest services repeatedly. There were delays in someone even answering the phone. The ...
Reviewed on Apr 20, 2026
Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
$293 nightly
The price is $293 total per night from Apr 27 to Apr 28
$293 total
Apr 27 - Apr 28
Total with taxes and fees
This all-inclusive property features a full-service spa, a nightclub, and 7 restaurants. Spend a day at the beach kayaking, or relax with free beach cabanas ...
We loved Dreams. The food and drinks were delicious. The property is beautiful and well maintained. Wish we could have stayed longer.
Reviewed on Apr 22, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Santa Pera hotel reviews by fellow wanderers
Hyatt Regency Panama City
5 out of 5
Posted 9 hours ago
Travelocity Verified Review
"Lobby, rooms and all facilities smelled amazing. Excellent conditions, well stocked, great service. "
A verified traveler stayed at Hyatt Regency Panama City
