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Top Salem hotels

Lake Jocassee ~ Easy Lake Access ~ Loved By Our Guests ~ Pet Friendly
"The most communicative host I’ve ever experienced! He was so thoughtful to call prior to my arrival to make sure I knew the best routes to take and offer up suggestions. Everything was easy- from finding the house to accessing the lake-only a 3 minute drive to the boat ramp! The house is well equipped ..."
Reviewed on Sep 2, 2026

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
"A unique experience, cabin provided everything needed except a mirror!! Close enough to town to get to stores and restaraunts easily but loved being far enough in the woods to enjoy the nature."
Reviewed on Sep 7, 2026

The Shepherd Hotel Downtown Clemson
"Absolutely perfect in every way!"
Reviewed on Sep 7, 2026

Clemson University's James F. Martin Inn
"Great location with two nice restaurants beautiful grounds and friendly people. We look forward to our next stay there."
Reviewed on Sep 8, 2026

Trailborn Highlands, Outdoor Collection by Marriott Bonvoy
"Loved everything but no pastries or bread and cold coffee"
Reviewed on Sep 7, 2026

Best Western Plus Clemson Hotel & Conference Center
"The hotel is nice. Updated and has a good restaurant and bar. However, our room was not clean. Crumbs and pretzels all over the floor. Hair all over the floor in the bathroom. The toilet had a mold ring. Based on cleanliness I will not stay there again."
Reviewed on Sep 8, 2026

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Inn @ Clemson
Salem Hotel & Travel Guide\n
Those planning to make memories in Salem are advised to book somewhere to sleep sooner rather than later, as they won't find a huge range of accommodation options near Salem's downtown.
The Three Pines View is a great base for your stay as it is one of the best-positioned Travelocity-listed accommodation options, one of just a small number of choices within an easy walk of the Salem downtown precinct.
The Half-Mile Farm is around 17 miles (28 kilometers) from the town center of Salem. Also, the Old Edwards Inn and Spa can be found 17 miles (27 kilometers) away. Other possible hotels include the Hampton Inn Clemson and the Hampton Inn & Suites Seneca-Clemson Area.
Why not get close to some more of the rolling hills that are common in Upstate South Carolina? A great idea is to take a few extra nights in some of the other fascinating areas of Upstate South Carolina. Modern visitors should visit regional places of interest or try your luck at mountain biking and then check in to a close Travelocity-registered lodging.
Greenville - Spartanburg is 35 miles (54 kilometers) to the east of Salem and is home to Falls Park on the Reedy and Bob Jones University. Greenville - Spartanburg rooms include the Courtyard by Marriott Greenville Downtown and Hampton Inn & Suites Greenville Downtown RiverPlace. 35 miles (53 kilometers) to the east of Salem, you will find Greenville Downtown, which is home to the Hyatt Regency Greenville and The Westin Poinsett Greenville. The Shoeless Joe Jackson Museum and Warehouse Theatre are some more popular places to experience when in Greenville Downtown.
Get yourself a serving of local sport by making a voyage to Bon Secours Wellness Arena, which is located 35 miles (53 kilometers) to the east of Salem. Modern visitors that enjoy the idea of booking a hotel in the vicinity, book a room in the Pettigru Place Bed & Breakfast or Holiday Inn Express Hotel & Suites Greenville Downtown.
For the modern traveler planning on arriving through Greenville-Spartanburg International Airport, you may choose to book a bed at Greenville Marriott, or Courtyard Greenville-Spartanburg by Marriott, which are both close.
Frequently asked questions
Recent Salem hotel reviews by fellow wanderers

The Skyline Lodge
"Great atmosphere. Perfect getaway"
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