Book Hotels in Salem, SC
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Top Salem hotels

Lake Jocassee retreat on two acres!! New hot tub, Devil’s Fork State Park
"A great location with lots of room and convenience. Comfortable beds and quiet."
Reviewed on May 26, 2026

North Keowee Family Lake House on Private Cove With Dock / 5 MIN FROM JOCASSEE
"We rented this house for 9 adults to enjoy the local lakes and celebrate some birthdays. We found the host to be responsive and helpful. The listing was accurate and informative. The house was well stocked with some essentials for cooking, coffee, toiletries and extra cozy blankets. The upgraded ..."
Reviewed on May 26, 2026

Lake Jocassee ~ Easy Lake Access ~ Loved By Our Guests ~ Pet Friendly
"All rooms were clean and the house was very close to the lake which made it so easy to get to the park. The fenced in front yard was very nice for my pup to have some freedom to roam outside while we were there."
Reviewed on Jun 4, 2026

The Shepherd Hotel Downtown Clemson
"Great place to stay"
Reviewed on Jun 7, 2026

Lakeside Lodge Clemson
"I enjoyed my stay and all the amenities were excellent! I can’t wait to return!"
Reviewed on Jun 7, 2026

Comfort Inn & Suites Clemson - University Area
"Quiet clean good for the price"
Reviewed on Jun 9, 2026

Best Western Plus Clemson Hotel & Conference Center
"This location was a few minutes away from Clemson, which was the goal. The place was clean, the beds comfortable and ice cold air conditioning. There was a restaurant attached to the hotel with great good, amazing portions and reasonable prices. The hotel also does breakfast which was one of the ..."
Reviewed on Jun 10, 2026

Inn @ Clemson
"The room was clean and the staff was very nice."
Reviewed on Jun 7, 2026

Quality Inn Seneca Clemson Area US-123
"Room was easy access to the parking bathroom was accessible for person with limited walking ability staff was very friendly and helpful the pool was not open"
Reviewed on Jun 9, 2026
Salem Hotel & Travel Guide\n
Those planning to make memories in Salem are advised to book somewhere to sleep sooner rather than later, as they won't find a huge range of accommodation options near Salem's downtown.
The Three Pines View is a great base for your stay as it is one of the best-positioned Travelocity-listed accommodation options, one of just a small number of choices within an easy walk of the Salem downtown precinct.
The Half-Mile Farm is around 17 miles (28 kilometers) from the town center of Salem. Also, the Old Edwards Inn and Spa can be found 17 miles (27 kilometers) away. Other possible hotels include the Hampton Inn Clemson and the Hampton Inn & Suites Seneca-Clemson Area.
Why not get close to some more of the rolling hills that are common in Upstate South Carolina? A great idea is to take a few extra nights in some of the other fascinating areas of Upstate South Carolina. Modern visitors should visit regional places of interest or try your luck at mountain biking and then check in to a close Travelocity-registered lodging.
Greenville - Spartanburg is 35 miles (54 kilometers) to the east of Salem and is home to Falls Park on the Reedy and Bob Jones University. Greenville - Spartanburg rooms include the Courtyard by Marriott Greenville Downtown and Hampton Inn & Suites Greenville Downtown RiverPlace. 35 miles (53 kilometers) to the east of Salem, you will find Greenville Downtown, which is home to the Hyatt Regency Greenville and The Westin Poinsett Greenville. The Shoeless Joe Jackson Museum and Warehouse Theatre are some more popular places to experience when in Greenville Downtown.
Get yourself a serving of local sport by making a voyage to Bon Secours Wellness Arena, which is located 35 miles (53 kilometers) to the east of Salem. Modern visitors that enjoy the idea of booking a hotel in the vicinity, book a room in the Pettigru Place Bed & Breakfast or Holiday Inn Express Hotel & Suites Greenville Downtown.
For the modern traveler planning on arriving through Greenville-Spartanburg International Airport, you may choose to book a bed at Greenville Marriott, or Courtyard Greenville-Spartanburg by Marriott, which are both close.
Frequently asked questions
Recent Salem hotel reviews by fellow wanderers

Best Western Plus Clemson Hotel & Conference Center
"This location was a few minutes away from Clemson, which was the goal. The place was clean, the beds comfortable and ice cold air conditioning. There was a restaurant attached to the hotel with great good, amazing portions and reasonable prices. The hotel also does breakfast which was one of the best I've seen at a hotel. So many options to pick from. The front seat person was very polite. I highly recommend this hotel."
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