Book Hotels in Puxico, MO
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Top Puxico hotels

Fairfield Inn & Suites by Marriott Poplar Bluff
3109 Oak Grove, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $112 total per night from Aug 3 to Aug 4
$112 total
Aug 3 - Aug 4
Total includes taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"The property itself is great. Friendly staff, clean room, clean common areas and convenient parking. The breakfast was a huge disappointment. Everything empty (and not refilled in a timely manner) and an absolute mess. Trash overflowing, food all over the counters and floors, tables unclean, etc. ..."
Reviewed on Jul 27, 2025

Drury Inn & Suites Poplar Bluff
2220 N Westwood Blvd, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Aug 17 to Aug 18
$106 total
Aug 17 - Aug 18
Total includes taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"All the staff was absolutely WONDERFUL!!!!"
Reviewed on Jul 7, 2025

Hampton Inn Poplar Bluff
2420 Crestwood Dr, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $109 total per night from Aug 17 to Aug 18
$109 total
Aug 17 - Aug 18
Total includes taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business ...
"We always have an excellent time at this Hampton inn. We never stay anywhere else when we come into town. However, this trip was a little different. It seemed like the air was not working in the common areas like the hallways, front desk, and dining area. It was super hot and humid in the areas. ..."
Reviewed on Jul 22, 2025

Holiday Inn Poplar Bluff by IHG
2781 N Westwood Blvd, Poplar Bluff, MO
Fully refundable
$97 nightly
The price is $110 total per night from Aug 7 to Aug 8
$110 total
Aug 7 - Aug 8
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"Na"
Reviewed on Jul 27, 2025

Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $83 total per night from Jul 30 to Jul 31
$83 total
Jul 30 - Jul 31
Total includes taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage is provided and the front desk is staffed ...
"The little self service store in the lobby is a nice touch. Pepsi supplies and runs it."
Reviewed on Jul 26, 2025

Comfort Inn Poplar Bluff North
2582 N Westwood Blvd, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $109 total per night from Aug 17 to Aug 18
$109 total
Aug 17 - Aug 18
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests ...
"Comfortable beds, very clean"
Reviewed on Jul 9, 2025

Travelodge by Wyndham Dexter
1608 E Business US 60, Dexter, MO
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $127 total per night from Jul 30 to Jul 31
$127 total
Jul 30 - Jul 31
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the business center. A restaurant, ...
"Good service"
Reviewed on Jul 22, 2025

Dexter Inn
1807 W Business US Highway 60, Dexter, MO
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $77 total per night from Jul 30 to Jul 31
$77 total
Jul 30 - Jul 31
Total includes taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk ...
"I always stay here when I’m in town. Great place"
Reviewed on Jun 19, 2025

Super 8 by Wyndham Poplar Bluff Missouri
2831 N Westwood Blvd, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from Aug 7 to Aug 8
$66 total
Aug 7 - Aug 8
Total includes taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"Julia was amazing"
Reviewed on Jul 22, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Puxico hotel reviews by fellow wanderers

Fairfield Inn & Suites by Marriott Poplar Bluff
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"The property itself is great. Friendly staff, clean room, clean common areas and convenient parking. The breakfast was a huge disappointment. Everything empty (and not refilled in a timely manner) and an absolute mess. Trash overflowing, food all over the counters and floors, tables unclean, etc. We ended up finding a restaurant and paying for breakfast. This is unfortunate because the free breakfast was an amenity that we specifically looked for since we are traveling with kids. "
A verified traveler stayed at Fairfield Inn & Suites by Marriott Poplar Bluff
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