Southern Illinois Vacation Packages 2025 from $421

Southern Illinois flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

The Wildwood Hotel

Save 100% on your flight

per person

Sep 5 - Sep 8

found 1 day ago

Roundtrip non-stop flight included

Raleigh (RDU) to St. Louis (STL)

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.

Ballpark Apartments by Barsala

Downtown St. Louis

Save 100% on your flight

per person

Sep 5 - Sep 8

found 1 day ago

Roundtrip non-stop flight included

Raleigh (RDU) to St. Louis (STL)

A gym is featured at this aparthotel, along with free WiFi in public areas and barbecue grills. A virtual front desk are provided for your convenience.

Moonrise Hotel

Delmar Loop

per person

Sep 5 - Sep 8

found 1 day ago

Roundtrip non-stop flight included

Raleigh (RDU) to St. Louis (STL)

The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy a meal from the a restaurant and perks like free self parking.

Ameristar Casino Resort and Spa

per person

Aug 9 - Aug 13

found 1 day ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to St. Louis (STL)

This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.

The Cheshire

per person

Sep 5 - Sep 8

found 1 day ago

Roundtrip non-stop flight included

Raleigh (RDU) to St. Louis (STL)

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free English breakfast each morning.

Top Southern Illinois hotels deals

Drury Plaza Hotel Mt. Vernon

145 North 44th Street , Mount Vernon, IL

Free Cancellation

Reserve now, pay when you stay

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This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Best Western Plus Pontoon Beach

4 Regency Pkwy, Granite City, IL

Free Cancellation

Reserve now, pay when you stay

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This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr, O'Fallon, IL

Free Cancellation

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This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.

Pool

Breakfast included

Drury Inn & Suites St. Louis Fairview Heights

12 Ludwig Dr, Fairview Heights, IL

Free Cancellation

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This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Red Lion Inn & Suites Pontoon Beach

1240 E Chain Of Rocks Rd, Granite City, IL

Free Cancellation

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This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour front desk can provide around-the-clock assistance.

Breakfast included

Pet friendly

Baymont by Wyndham Effingham

1811 W Fayette Avenue, I-57 & 70 Exit 159, Effingham, IL

Free Cancellation

Reserve now, pay when you stay

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This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free perks like buffet breakfast and free self parking.

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Southern Illinois University

4.5/5(173 reviews)

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

Garden of the Gods Recreation Area

5/5(6 reviews)

See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.

Monk's Mound covers almost 14 acres and rises 100 feet. A part of the larger ancient city of Cahokia that at its peak housed 10-15 thousand people.

Cahokia Mounds State Historic Site

4.5/5(4 reviews)

You can learn about the history of Collinsville when you stop by Cahokia Mounds State Historic Site. Discover the great live music in this walkable area, or seek out the local tours.

Frequently asked questions

How much are vacation packages to Southern Illinois?

Your travel fantasies can become a reality in Southern Illinois for as little as $421. Our package deals include flights and hotels, so booking your trip will be a piece of cake. The only thing you'll need to worry about is what amazing attraction you'll head to first.

Where can I get the best vacation package deals for Southern Illinois?

With at least 400 air carriers and 1,000,000 properties around the world, it's tough to beat Travelocity. Take advantage of our comprehensive range and grab an affordable Southern Illinois vacation package. Doesn't it feel amazing when travel is that easy?

Why should I purchase my Southern Illinois vacation package via Travelocity?

The three S's --- savings, support and a stress-free booking --- are just the beginning. Enjoy a fulfilling travel experience knowing you can rely on our expert team of customer support professionals 24/7. With the Travelocity Price Match Guarantee, you can rest easy knowing you're getting the best deal available.

Can I save on my Southern Illinois car rental if I bundle it with a hotel or flight?

You can with our Southern Illinois vacation packages. With one of these, there are lots of ways to stretch your budget further. Combine any two or more car, flight, hotel and tour bookings and watch the savings start to pile up. With your own set of wheels, all the landmarks around Southern Illinois are just a road trip away.

Which airport is best for Southern Illinois?

Williamson County Regional Airport (MWA) is the main airport that offers flights in and out of Southern Illinois.

What is there to do in Southern Illinois?

Southern Illinois boasts hidden gems at every turn, however make sure you see Shawnee National Forest and Southern Illinois University while you're in town. These two attractions are popular with visitors.