Southern Illinois Vacation Packages 2026 from $528

Southern Illinois flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

River City Casino & Hotel

Save 100% on your flight

$528

per person

Nov 3 - Nov 10

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference space. Enjoy the 24-hour gym and perks like free self parking.

The Wildwood Hotel

$811

per person

Nov 3 - Nov 10

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.

Residence Inn by Marriott St. Louis West County

$681

per person

Nov 3 - Nov 10

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

This hotel features an indoor pool and a 24-hour gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free full breakfast each morning.

Moonrise Hotel

Delmar Loop

Save 100% on your flight

$645

per person

Nov 3 - Nov 10

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy a meal from the a restaurant and perks like free self parking.

Crowne Plaza St. Louis Airport by IHG

Save 100% on your flight

$616

per person

Nov 3 - Nov 10

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy the gym and perks like a free area shuttle.

Top Southern Illinois hotels deals

Drury Inn & Suites St. Louis Fairview Heights

12 Ludwig Dr Fairview Heights IL

Free Cancellation

Reserve now, pay when you stay

$94 nightly

$106 total

Sep 20 - Sep 21

Total with taxes and fees

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Drury Plaza Hotel Mt. Vernon

145 North 44th Street Mount Vernon IL

Free Cancellation

Reserve now, pay when you stay

$111 nightly

$125 total

Sep 20 - Sep 21

Total with taxes and fees

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Quality Inn O'Fallon - St. Louis - Shiloh

1409 W US 50 O'Fallon IL

Free Cancellation

$67 nightly

$77 total

Oct 5 - Oct 6

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour business center. There's an indoor pool on site, and laundry facilities and free newspapers are also offered.

Pool

Breakfast included

Drury Inn & Suites St. Louis O'Fallon, IL

1118 Central Park Drive O'Fallon IL

Free Cancellation

Reserve now, pay when you stay

$106 nightly

$123 total

Sep 20 - Sep 21

Total with taxes and fees

Pool

Hot Tub

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL

Free Cancellation

Reserve now, pay when you stay

$54 nightly

$62 total

Sep 21 - Sep 22

Total with taxes and fees

This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.

Pool

Breakfast included

Ramada by Wyndham Effingham

1606 W Fayette Avenue Effingham IL

Free Cancellation

Reserve now, pay when you stay

$67 nightly

$75 total

Sep 29 - Sep 30

Total with taxes and fees

A gym is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. Staff at the 24-hour front desk can provide around-the-clock assistance.

Breakfast included

Pet friendly

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

9.8/10 (63 reviews)

See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.

See properties

Frequently asked questions

How much are vacation packages to Southern Illinois?

Your travel fantasies can become a reality in Southern Illinois for as little as $528. Our package deals include flights and hotels, so booking your trip will be a piece of cake. The only thing you'll need to worry about is what amazing attraction you'll head to first.

Where can I get the best vacation package deals for Southern Illinois?

With at least 400 air carriers and 1,000,000 properties around the world, it's tough to beat Travelocity. Take advantage of our comprehensive range and grab an affordable Southern Illinois vacation package. Doesn't it feel amazing when travel is that easy?

Why should I purchase my Southern Illinois vacation package via Travelocity?

The three S's — savings, support and a stress-free booking — are just the beginning. Enjoy a fulfilling travel experience knowing you can rely on our expert team of customer support professionals 24/7. With the Travelocity Price Match Guarantee, you can rest easy knowing you're getting the best deal available.

Can I save on my Southern Illinois car rental if I bundle it with a hotel or flight?

You can with our Southern Illinois vacation packages. With one of these, there are lots of ways to stretch your budget further. Combine any two or more car, flight, hotel and tour bookings and watch the savings start to pile up. With your own set of wheels, all the landmarks around Southern Illinois are just a road trip away.

Which airport is best for Southern Illinois?

Williamson County Regional Airport (MWA) is the main airport that offers flights in and out of Southern Illinois.

What is there to do in Southern Illinois?

Southern Illinois boasts hidden gems at every turn, however make sure you see Shawnee National Forest and Southern Illinois University while you're in town. These two attractions are popular with visitors.