Explore West Main Historic District Spa Hotels & Wellness Resorts
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Top West Main Historic District Spa Resorts & Hotels

21c Museum Hotel Louisville
700 W Main Street Louisville KY
Free Cancellation
Reserve now, pay when you stay
$183 nightly
The price is $216 total per night
$216 total
Nov 23 - Nov 24
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

Louisville Marriott Downtown
280 West Jefferson Street Louisville KY
Free Cancellation
Reserve now, pay when you stay
$171 nightly
The price is $201 total per night
$201 total
Nov 26 - Nov 27
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Galt House Hotel Trademark Collection by Wyndham
140 North Fourth Street Louisville KY
Free Cancellation
Reserve now, pay when you stay
$93 nightly
The price is $110 total per night
$110 total
Nov 26 - Nov 27
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

Residence Inn by Marriott Louisville Downtown
333 East Market Street Louisville KY
Free Cancellation
Reserve now, pay when you stay
$96 nightly
The price is $113 total per night
$113 total
Dec 22 - Dec 23
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...

Seelbach Hilton Louisville Downtown
500 S 4th St Louisville KY
Free Cancellation
Reserve now, pay when you stay
$127 nightly
The price is $149 total per night
$149 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
West Main Historic District hotels essential information
Accommodation | 2,073 hotels |
|---|---|
Lowest Price | $110 |
Highest Price | $216 |
Popular hotels | Galt House Hotel Trademark Collection by Wyndham, 21c Museum Hotel Louisville, Louisville Marriott Downtown, Residence Inn by Marriott Louisville Downtown, Seelbach Hilton Louisville Downtown |
Recent West Main Historic District hotel reviews by fellow wanderers

Galt House Hotel Trademark Collection by Wyndham
5 out of 5
Posted 5 days ago
Travelocity Verified Review
"Clean room"
A verified traveler stayed at Galt House Hotel Trademark Collection by Wyndham

21c Museum Hotel Louisville
5 out of 5
Posted 7 days ago
Travelocity Verified Review
"Excellent in every way. The art museum was an added bonus!!!"
A verified traveler stayed at 21c Museum Hotel Louisville
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