Explore West Main Historic District Spa Hotels & Wellness Resorts

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Top West Main Historic District Spa Resorts & Hotels

21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 out of 5
700 W Main Street Louisville KY
Free Cancellation
Reserve now, pay when you stay
$165 nightly
The price is $194 total per night
$194 total
Nov 15 - Nov 16
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Louisville Marriott Downtown

Louisville Marriott Downtown

4 out of 5
280 West Jefferson Street Louisville KY
Free Cancellation
Reserve now, pay when you stay
$197 nightly
The price is $232 total per night
$232 total
Nov 13 - Nov 14
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Residence Inn by Marriott Louisville Downtown

Residence Inn by Marriott Louisville Downtown

3 out of 5
333 East Market Street Louisville KY
Free Cancellation
Reserve now, pay when you stay
$103 nightly
The price is $121 total per night
$121 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

4 out of 5
500 S 4th St Louisville KY
Free Cancellation
Reserve now, pay when you stay
$165 nightly
The price is $194 total per night
$194 total
Oct 29 - Oct 30
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
Free Cancellation
Reserve now, pay when you stay
$140 nightly
The price is $165 total per night
$165 total
Nov 8 - Nov 9
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Don't see what you're looking for?
See all available properties in West Main Historic District
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

West Main Historic District hotels essential information

Accommodation
2,128 hotels
Lowest Price
$121
Highest Price
$232
Popular hotels
Galt House Hotel Trademark Collection by Wyndham, 21c Museum Hotel Louisville, Louisville Marriott Downtown, Residence Inn by Marriott Louisville Downtown, Seelbach Hilton Louisville Downtown

Recent West Main Historic District hotel reviews by fellow wanderers

Louisville Marriott Downtown

Louisville Marriott Downtown

5 out of 5
Posted 16 hours ago
Travelocity Verified Review
"We really enjoyed our stay here. The hotel is centrally located and convenient to explore different areas of the city. The fitness center and studio spaces are large and top of the line. Our room was incredibly quiet and private."
A verified traveler stayed at Louisville Marriott Downtown
Louisville Marriott Downtown