Explore 49 Luxury Hotels in Mississippi Gulf Coast

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Best Luxury Hotels in Mississippi Gulf Coast

Beau Rivage

Beau Rivage

875 Beach Blvd, Biloxi, MS
$160 nightly
The price is $179 total per night from Jun 1 to Jun 2
$179 total
Jun 1 - Jun 2
Total includes taxes and fees
This resort features a casino, a full-service spa, and 10 restaurants. Relax with a drink at one of the 7 bars/lounges and enjoy perks like free valet parking. ...
9/10 Wonderful! (1,410 reviews)
"Amazing!!"

Reviewed on May 19, 2025

Beau Rivage
White House Hotel

White House Hotel

1230 Beach Blvd, Biloxi, MS
$156 nightly
The price is $175 total per night from May 29 to May 30
$175 total
May 29 - May 30
Total includes taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public ...
8.8/10 Excellent! (1,001 reviews)
"Loved the historical aspect of this hotel. It’s been remodeled and really nice."

Reviewed on May 18, 2025

White House Hotel
Margaritaville Resort Biloxi

Margaritaville Resort Biloxi

195 Beach Blvd, Biloxi, MS
Fully refundableReserve now, pay when you stay
$230 nightly
The price is $255 total per night from May 29 to May 30
$255 total
May 29 - May 30
Total includes taxes and fees
A water park, 3 restaurants, and a lazy river are all featured at this hotel. Bring the family and enjoy the waterslide, arcade/game room, and kid-friendly dining. ...
8.6/10 Excellent! (4,607 reviews)
Cheese burger in paradise
"Too bad Jimmy is gone.. Parrot heads forever!!!"

Reviewed on May 23, 2025

Margaritaville Resort Biloxi
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IP Casino Resort Spa - Biloxi

IP Casino Resort Spa - Biloxi

850 Bayview Ave, Biloxi, MS
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $153 total per night from May 29 to May 30
$153 total
May 29 - May 30
Total includes taxes and fees
This resort features a casino, a full-service spa, and a nightclub. Enjoy a meal in one of the 7 restaurants and free perks like free self parking and WiFi in ...
8.4/10 Very Good! (4,877 reviews)
"Giod"

Reviewed on May 27, 2025

IP Casino Resort Spa - Biloxi
Microtel Inn & Suites by Wyndham Hattiesburg

Microtel Inn & Suites by Wyndham Hattiesburg

105 Westover Dr, Hattiesburg, MS
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $71 total per night from Jun 15 to Jun 16
$71 total
Jun 15 - Jun 16
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
8.2/10 Very Good! (1,003 reviews)
"M"

Reviewed on May 23, 2025

Microtel Inn & Suites by Wyndham Hattiesburg
Golden Nugget Biloxi

Golden Nugget Biloxi

151 Beach Blvd, Biloxi, MS
$102 nightly
The price is $113 total per night from Jun 26 to Jun 27
$113 total
Jun 26 - Jun 27
Total includes taxes and fees
This resort features a casino, a full-service spa, and a nightclub. Business travelers can take advantage of the express check-out. You'll find 4 restaurants ...
8/10 Very Good! (2,346 reviews)
"Staff was friendly and rm was perfect"

Reviewed on May 27, 2025

Golden Nugget Biloxi
Harrah's Gulf Coast

Harrah's Gulf Coast

280 Beach Boulevard, Biloxi, MS
$104 nightly
The price is $116 total per night from May 29 to May 30
$116 total
May 29 - May 30
Total includes taxes and fees
This resort features a casino, a full-service spa, and 8 restaurants. Traveling on business? Take advantage of the express check-out and onsite conference space. ...
7.6/10 Good! (1,279 reviews)
"Heyyyyy"

Reviewed on May 22, 2025

Harrah's Gulf Coast
Magnolia Inn

Magnolia Inn

6655 Highway 49 N., Hattiesburg, MS
A gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk can provide around-the-clock ...
7/10 Good! (553 reviews)
"."

Reviewed on Apr 27, 2025

Magnolia Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Mississippi Gulf Coast

Mississippi Gulf Coast Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Mississippi Gulf Coast luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Mississippi Gulf Coast to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Mississippi Gulf Coast will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Mississippi Gulf Coast, and plan your next opulent escape.


Mississippi Gulf Coast hotels essential information

Accommodation
3,026 hotels
Lowest Price
$71
Highest Price
$335
Popular hotels
Beau Rivage, Margaritaville Resort Biloxi, White House Hotel, IP Casino Resort Spa - Biloxi, Golden Nugget Biloxi, Magnolia Inn, Harrah's Gulf Coast, Microtel Inn & Suites by Wyndham Hattiesburg

Popular Luxury Stays in Mississippi Gulf Coast

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