Explore 49 Luxury Hotels in North Central Florida

Name: Baymont By Wyndham Gainesville I-75
Price range: $82 total
Rating: 5.2

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Best Luxury Hotels in North Central Florida

Best Western Waldo Inn and Suites

17230 Ne Us Highway 301, Waldo, FL

Fully refundableReserve now, pay when you stay

$85 nightly

$96 total

Nov 2 - Nov 3

Total with taxes and fees

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...

8.8/10 Excellent! (930 reviews)

A great alternative to the expensive hotels downtown for UF Homecoming. Very clean rooms.

Reviewed on Oct 21, 2025

Americas Best Value Inn Lake City

3835 West US Highway 90, Lake City, FL

Fully refundableReserve now, pay when you stay

$67 nightly

$76 total

Oct 29 - Oct 30

Total with taxes and fees

An outdoor pool is featured at this motel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. ...

8.6/10 Excellent! (1,002 reviews)

Great Value, Clean, and Comfortable

Clean, simple, and exactly what I needed! Staff was super kind and helpful. Only slight complaint is it seemed the noise was sneaking through the door of my road-facing room, but it didn’t bother me once I went to bed.

Reviewed on Oct 17, 2025

Driftwood Inn

2764 W US Hwy 90, Lake City, FL

Fully refundable

$61 nightly

$69 total

Oct 26 - Oct 27

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...

7.8/10 Good! (747 reviews)

They were very nice and it was clean and comfortable.

Reviewed on Aug 31, 2025

Palms Garden Inn

14113 S. US Hwy 441, I -75 Exit 414, Lake City, FL

Fully refundableReserve now, pay when you stay

$65 nightly

$73 total

Oct 27 - Oct 28

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Express check-out and laundry facilities are also provided.

7.4/10 Good! (567 reviews)

I reserved this hotel at a much lower rate than its competitors, so I came in with reasonable expectations. The check in was easy and the host was friendly. The room was pretty clean, although dated (but that was very much expected). I do want to make a point that other people review other hotels ...

Reviewed on Oct 5, 2025

Gainesville Lodge

413 West University Ave, Gainesville, FL

Fully refundableReserve now, pay when you stay

$300 nightly

$338 total

Nov 14 - Nov 15

Total with taxes and fees

Free WiFi in public areas is available at this motel. Take advantage of the free self parking.

7.2/10 Good! (547 reviews)

The property is an old-style motel, but the rooms have been updated and are very lovely and cute, with plenty of K-cups and towels. My only complaint in the tiny, and I mean tiny (one can), refrigerator. Rooms need a small usable fridge, and a microwave would be a bonus. I would stay there again, ...

Reviewed on Oct 6, 2025

WoodSpring Suites Gainesville I-75

5505 SW 41st Blvd, Gainesville, FL

Fully refundableReserve now, pay when you stay

$64 nightly

$72 total

Oct 26 - Oct 27

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-out. The front ...

6.2/10 (1,008 reviews)

Nice place

Reviewed on Sep 7, 2025

Days Inn by Wyndham Gainesville University I-75

920 Nw 69th Ter, Gainesville, FL

Fully refundableReserve now, pay when you stay

$72 nightly

$81 total

Oct 26 - Oct 27

Total with taxes and fees

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...

5.4/10 (1,000 reviews)

The rooms need some up keeping and maintenance. However it was clean and accessible to near by restaurants, shops. It was worth for the cost of stay

Reviewed on Oct 13, 2025

Baymont By Wyndham Gainesville I-75

6901 NW 4th Boulevard, Gainesville, FL

Fully refundableReserve now, pay when you stay

$73 nightly

$82 total

Oct 27 - Oct 28

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling for business? Take advantage of the business center, laundry ...

5.2/10 (1,000 reviews)

Great

Reviewed on Sep 11, 2025

Don't see what you're looking for?

See all available properties in North Central Florida

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5 star hotels in North Central Florida

The Equestrian Hotel

8510 NW 17th Lane, Ocala, FL

$296 nightly

$330 total

Oct 26 - Oct 27

Total with taxes and fees

9.6/10 Exceptional! (555 reviews)

North Central Florida Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the North Central Florida luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in North Central Florida to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in North Central Florida will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in North Central Florida, and plan your next opulent escape.

North Central Florida hotels essential information

Accommodation	2,534 hotels
Lowest Price	$69
Highest Price	$338
Popular hotels	Baymont By Wyndham Gainesville I-75, Palms Garden Inn, Americas Best Value Inn Lake City, Driftwood Inn, Days Inn by Wyndham Gainesville University I-75, WoodSpring Suites Gainesville I-75, Best Western Waldo Inn and Suites, Gainesville Lodge