Book Hotels in Cairo, MO
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Top Cairo hotels

Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness
Cairo MO
This vacation home featured laundry facilities and barbecue grills.
My wife and I had a wonderful time at the cabin—it’s a beautiful house, incredibly clean and comfortable, and had everything we could possibly need to enjoy our stay. We won’t look anywhere else the next time we want a quiet weekend of rest and relaxation!
Reviewed on Mar 23, 2026

Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri
Macon MO
This lodge featured laundry facilities and barbecue grills.
Family reunion
The rooms were very clean and comfortable. It was very hot and humid outside, but the AC and ceiling fans kept up well. The host answered questions quickly. We had rain (and lots of it) every day but our last, but had a good time anyway; making use of the game room, large dining areas for other games, ...
Reviewed on Jul 28, 2025

Teal Nest - at The Lodges of Long Branch
Bevier Township MO
$165 nightly
The price is $170 total per night from Apr 1 to Apr 2
$170 total
Apr 1 - Apr 2
Total with taxes and fees
This cabin features barbecue grills.
It was a small space but perfect for just the 2 of us.
Reviewed on Feb 2, 2026

Comfort Inn & Suites Moberly
1801 W Outer Rd Moberly MO
$104 nightly
The price is $117 total per night from Apr 4 to Apr 5
$117 total
Apr 4 - Apr 5
Total with taxes and fees
A gym, free self parking, and free newspapers are featured at this hotel. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. A ...
Breakfast was better than expected. Beds were comfortable but bathrooms were clean but old. Staff was friendly
Reviewed on Mar 28, 2026

Simple Rewards Inn Shelbina
711 North Highway 15 Shelbina MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $88 total per night from Apr 1 to Apr 2
$88 total
Apr 1 - Apr 2
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
Clean room
Reviewed on Mar 11, 2026

Super 8 by Wyndham Macon
203 E Briggs Dr Macon MO
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $100 total per night from Apr 10 to Apr 11
$100 total
Apr 10 - Apr 11
Total with taxes and fees
This motel features free WiFi in public areas, barbecue grills, and free self parking. Enjoy the free on-the-go breakfast each morning. Staff at the 24-hour ...
We were very pleased with our stay at this motel.
Reviewed on Mar 29, 2026

OYO Travelier Motel
201 E Briggs Dr Macon MO
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $81 total per night from Apr 15 to Apr 16
$81 total
Apr 15 - Apr 16
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free parking. Guests will appreciate freebies like continental breakfast and free self ...
There were bugs in bed and toliet and moved rooms it seemed ok but other ppl with refused to stay after all that so went to a different hotel The guy did refund money i have stayed at this hotel a few years ago never any issues like this
Reviewed on Mar 8, 2026

Americas Best Value Inn & Suites Macon at Sunset Dr
28933 Sunset Drive Macon MO
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $77 total per night from Apr 14 to Apr 15
$77 total
Apr 14 - Apr 15
Total with taxes and fees
A restaurant and a bar/lounge are featured at this motel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self ...
The room was clean, the bathroom was clean and the bedding smelled fresh. Nothing fancy, but we just wanted to sleep.
Reviewed on Mar 22, 2026

Super 8 by Wyndham Moberly MO
300 E Highway 24 Moberly MO
$68 nightly
The price is $76 total per night from Apr 12 to Apr 13
$76 total
Apr 12 - Apr 13
Total with taxes and fees
Free self parking is available and the motel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Cairo hotel reviews by fellow wanderers

Super 8 by Wyndham Macon
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"We were very pleased with our stay at this motel."
A verified traveler stayed at Super 8 by Wyndham Macon
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