Explore top 2026 4 Star Hotels in Panama Canal Zone

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Top Panama Canal Zone 4 Star hotels

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$119 nightly
The price is $131 total per night from Mar 5 to Mar 6
$131 total
Mar 5 - Mar 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
8.6/10 Excellent! (2,451 reviews)
Very clean room and surroundings. Staff at restaurant at for dinner excellent but one female in particular deserves one star at best. Should’ve gotten her name, but I did not.

Reviewed on Feb 24, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
$221 nightly
The price is $243 total per night from Mar 3 to Mar 4
$243 total
Mar 3 - Mar 4
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
8.4/10 Very Good! (1,432 reviews)
The room was excellent served was excellent. Everything was 100% service breakfast pool rooms view 10+ I strongly recommend this hotel. They grows in the breakfast, Melissa. Magella list Daniela Monica, the pool, amazing amazing girls. They were so helpful and caring all the way. The courtesy was ...

Reviewed on Feb 24, 2026

Opens in a new windowMegapolis Hotel Panamá
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $183 total per night from Mar 3 to Mar 4
$183 total
Mar 3 - Mar 4
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9/10 Wonderful! (1,051 reviews)
The lobby and restaurant are fabulous, very nice to have a large patio area to catch some sun as well. The pool was incredibly loud, electronic music which made it impossible to sit by and relax.

Reviewed on Feb 22, 2026

Opens in a new windowLas Americas Golden Tower Panama
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall Panama City Panama
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $177 total per night from Mar 15 to Mar 16
$177 total
Mar 15 - Mar 16
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
9/10 Wonderful! (1,012 reviews)
Really nice and great breakfast

Reviewed on Feb 23, 2026

Opens in a new windowMarriott Panama Hotel
Novotel Panama City

Novotel Panama City

4 out of 5
Calle Jose I. Fabrega y Thais de Pons Panama City Panama
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $120 total per night from Mar 14 to Mar 15
$120 total
Mar 14 - Mar 15
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. There's fun for all ages with a free kid's club and a playground, and families will appreciate ...
9.2/10 Wonderful! (1,112 reviews)
Clean room nice staff

Reviewed on Feb 22, 2026

Opens in a new windowNovotel Panama City
Studio Coliving

Studio Coliving

4.5 out of 5
Av. Ricardo Arango y, Av. Federico Boyd Panama City Panama
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowStudio Coliving
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $128 total per night from Feb 25 to Feb 26
$128 total
Feb 25 - Feb 26
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express ...
8.6/10 Excellent! (1,573 reviews)
Great

Reviewed on Feb 23, 2026

Opens in a new windowDecapolis Hotel Panama City
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $104 total per night from Mar 4 to Mar 5
$104 total
Mar 4 - Mar 5
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
9.6/10 Exceptional! (1,163 reviews)
The room was amazing , cleaned very regularly

Reviewed on Feb 23, 2026

Opens in a new windowRamada Plaza by Wyndham Panama Punta Pacifica
American Trade Hotel

American Trade Hotel

4.5 out of 5
Plaza Herrera Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
$227 nightly
The price is $252 total per night from Mar 26 to Mar 27
$252 total
Mar 26 - Mar 27
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
9.4/10 Exceptional! (662 reviews)
The hotel was charming and clean. The staff was friendly, polite and helpful. I especially liked the water pressure and the waterfall-like shower.

Reviewed on Feb 23, 2026

Opens in a new windowAmerican Trade Hotel
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $148 total per night from Mar 8 to Mar 9
$148 total
Mar 8 - Mar 9
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
8.6/10 Excellent! (1,011 reviews)
The staff was courteous and overall very helpful. The spaces were clean. They had easy access to taxis if you needed them and the breakfast buffet, and restaurants were delicious. We did ask for extra water a few times and it was stated it would be brought up and never was. Other than that, the stay ...

Reviewed on Feb 23, 2026

Opens in a new windowSheraton Grand Panama
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4 Star Hotels Panama Canal Zone

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Panama Canal Zone 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Panama Canal Zone will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Panama Canal Zone, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Panama Canal Zone hotel reviews by fellow wanderers