Explore top 2026 4 Star Hotels in Central Missouri

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Top Central Missouri 4 Star hotels

Lodge Of Four Seasons Golf Resort, Marina & Spa

315 Four Seasons Dr. Lake Ozark MO

Fully refundableReserve now, pay when you stay

$122 nightly

$133 total

Jul 12 - Jul 13

Total with taxes and fees

This resort features a golf course, a full-service spa, and a marina. Traveling on business? Take advantage of the free WiFi in public areas, conference center, ...

7.4/10 Good! (1,197 reviews)

"For the amount of money paid, you would think there would be a microwave andrefrigerator in the room. No cleaning service no cell service and spotty Wi-Fi. The shower was terrible hot water to cold water without changing the knob no steady temperature half of the restaurants not open or closed early ..."

Reviewed on Jun 28, 2026

Drury Plaza Hotel Columbia East

3100 Interstate 70 Dr. SE Columbia MO

Fully refundableReserve now, pay when you stay

$94 nightly

$106 total

Jul 12 - Jul 13

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

9.6/10 Exceptional! (1,509 reviews)

"Our king size bedroom was very nicely updated, the shower was one of the best that I have seen in a hotel. Breakfast was great, manager reception was good but Drury Inn need to change up what they do on Saturday evenings. Pulled pork and baked potatoes every time gets redundant."

Reviewed on Jun 29, 2026

The Broadway Columbia - a DoubleTree by Hilton

1111 E Broadway Columbia MO

Fully refundableReserve now, pay when you stay

$111 nightly

$126 total

Jul 12 - Jul 13

Total with taxes and fees

This hotel features 2 bars/lounges and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet ...

9.4/10 Exceptional! (1,004 reviews)

"This was our second stay in a year, here, and we have really enjoyed this hotel. It is extremely close to where we wanted to be in Columbia, and I love that the most. We had breakfast there - food was great. No complaints on the room, other than for the suites, it would be nice to have some paper ..."

Reviewed on Jun 28, 2026

Camden on the Lake Resort & Spa

2359 Bittersweet Road Lake Ozark MO

$176 nightly

$188 total

Jun 30 - Jul 1

Total with taxes and fees

This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas and free ...

9.2/10 Wonderful! (1,006 reviews)

"Hotel was very nice. Staff and grounds were great. The reason for giving a neutral review is our room was right next to loud live music until 1AM. I feel we should have been warned about the room at check in or before and given an option for a room on the other side of the hotel. Please be sure to ..."

Reviewed on Jun 29, 2026

voco The Tiger Hotel Columbia, MO by IHG

23 S 8th St Columbia MO

Fully refundable

$163 nightly

$185 total

Jul 2 - Jul 3

Total with taxes and fees

A nightclub, 3 restaurants, and a 24-hour gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, ...

9/10 Wonderful! (1,002 reviews)

"Was not clean enough for the price! Instead of a 9.3 star review it should’ve been a 5. They must have bought that 9.3 star review somehow"

Reviewed on Jun 25, 2026

DoubleTree by Hilton Hotel Jefferson City

422 Monroe St Jefferson City MO

Fully refundableReserve now, pay when you stay

$122 nightly

$140 total

Jul 5 - Jul 6

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and WiFi in public areas. ...

8.4/10 Very Good! (756 reviews)

"Beautiful hotel and great staff. We will definitely stay again."

Reviewed on Jun 27, 2026

Lakefront & Boat Slip: Osage Beach Retreat!

Osage Beach MO

$303 nightly

$323 total

Jul 21 - Jul 22

Total with taxes and fees

A marina and an outdoor pool are featured at this smoke-free apartment. Guests will appreciate free perks like free self parking and WiFi in public areas. Barbecue ...

10/10 Exceptional! (1 review)

"Beautiful place! Not hard to find at all! Very nice owners"

Reviewed on Apr 7, 2025

Boonville Luxury Lodging

519 High St Boonville MO

This bed & breakfast features free self parking and free WiFi in public areas. Enjoy the free local cuisine breakfast each morning. A garden and a communal living ...

10/10 Exceptional! (47 reviews)

"The Grand Victorian Manor at Boonville, Missouri is a rare find. We stayed in the Rose Room. The accommodations were excellent. The hosts were superb. I would highly recommend this B&B."

Reviewed on Jun 1, 2026

Get rates

Osage Beach Condo w/ Private Deck & Lake Views!

Osage Beach MO

This apartment doesn't skimp on freebies - guests receive free WiFi and free self parking. An outdoor pool is also provided.

Get rates

Lakefront Osage Beach Abode w/ Grill & Pool Access

Osage Beach MO

A marina and an outdoor pool are featured at this smoke-free apartment. Business travelers can take advantage of the free WiFi in public areas. Free self parking ...

Get rates

Don't see what you're looking for?

See all available properties in Central Missouri

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Central Missouri

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Central Missouri 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Central Missouri will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Central Missouri, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Central Missouri hotel reviews by fellow wanderers

Drury Plaza Hotel Columbia East

5 out of 5

Posted 5 hours ago

Travelocity Verified Review

A verified traveler stayed at Drury Plaza Hotel Columbia East

Schmidt's Creek Hotel

5 out of 5

Posted 6 hours ago

Travelocity Verified Review

"I truly enjoyed this place. Jessica and Becky up front were amazing. Friendly and great service. My room was clean and nice. Comfy bed and great hot water shower. A microwave would have been great but there was only a fridge. I Only had one big complaint which I did address with the manager and that was the consistent door slamming of the housekeepers. It would go on all morning very loud and hard, shaking the room. It was very disruptive and inconsiderate. They also needed a new luggage cart desperately. There was only one and it was tiny, held together with duct tape and the wheels barely rolled. Management was concerned and wrote down my complaints that they were going to address. Overall, I still liked this place very much and I will go back. Hopefully it'll be quieter next time."

A verified traveler stayed at Schmidt's Creek Hotel

Inn at Grand Glaize

5 out of 5

Posted 9 hours ago

Travelocity Verified Review

"Our entire was better than expected, they were fantastic even before we walked in the door. The door man was extremely friendly and easy to talk to. The desk staff were just absolutely amazing and friendly. Our room was great, but next time we want a room on the lake side 😉. The hot tub was probably one of the best I have ever been in, the size and the jets just really made my day. You run out of time before you run out of things to do. It was a wonderful experience."

A verified traveler stayed at Inn at Grand Glaize

Stoney Creek Hotel Columbia

4 out of 5

Posted 13 hours ago

Travelocity Verified Review

"We enjoyed the cottage that we stayed in, it gave us a little bit more feel of being in a log cabin. However, the property is run down and I'm hoping that they're just not putting any more money into it because they see a renovation coming. Our room and the lobby were the only places that were an appropriate temperature, but the elevators, hallways and breakfast area were very warm each day. Breakfast was good enough, the pool was a hit with the kids and the location was just right. I called the property 10 or so times over a couple of hours when we were headed in and no one picked up, not once. A few improvements would go a long way, such as having the front desk number on the room phone (wasn't zero), some deep cleaning in the hallways and breakfast area and making sure the external doors don't get stuck open for security. Wouldnt stay here again unless they get a renovation."

A verified traveler stayed at Stoney Creek Hotel Columbia