Explore top 2026 4 Star Hotels in Greenville - Spartanburg

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Top Greenville - Spartanburg 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$298 nightly
The price is $327 total per night from Mar 17 to Mar 18
$327 total
Mar 17 - Mar 18
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
9.6/10 Exceptional! (463 reviews)
Perfectly located to walk to the river, downtown and peace center. Gorgeous asthetic, and pristine rooms, we loved the restaurant also! Staff we courteous and helpful in everyway. 10/10

Reviewed on Mar 2, 2026

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $191 total per night from Apr 5 to Apr 6
$191 total
Apr 5 - Apr 6
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. ...
9.8/10 Exceptional! (676 reviews)
We stayed overnight for an appointment the next day in the area. It was a lovely stay. We had drinks & lunch in the bar but went out to dinner because it was Sunday and the restaurant was closed. The food and service in the bar area were great! My complaint is that we left clothes in the closet and ...

Reviewed on Mar 14, 2026

Opens in a new windowHotel Hartness
Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa

4 out of 5
101 Falls Park Dr Greenville SC
$114 nightly
The price is $126 total per night from Mar 22 to Mar 23
$126 total
Mar 22 - Mar 23
Total with taxes and fees
A 24-hour gym, self parking, and laundry facilities are featured at this apartment. Express check-in and express check-out are also provided.
9.2/10 Wonderful! (799 reviews)
You never sent me the access code so I stood outside the hotel for over an hour and also your phone number is invalid.

Reviewed on Mar 16, 2026

Opens in a new windowMint House Greenville Downtown by Kasa
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St Greenville SC
Fully refundableReserve now, pay when you stay
$189 nightly
The price is $208 total per night from Mar 29 to Mar 30
$208 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...
9.2/10 Wonderful! (1,000 reviews)
I think the

Reviewed on Mar 4, 2026

Opens in a new windowThe Westin Poinsett Greenville
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E Greenville SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $130 total per night from Apr 3 to Apr 4
$130 total
Apr 3 - Apr 4
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-in, ...
8.6/10 Excellent! (632 reviews)
The staff was ABSOLUTELY, ABSOLUTELY AMAZING!!! They were very courteous and helpful when we first walked through the main entrance and throughout our stay!!! Will definitely stay at this location again!!💕💕

Reviewed on Mar 3, 2026

Opens in a new windowGreenville Marriott
The Station by Compo Hotels

The Station by Compo Hotels

4 out of 5
745 Old Buncombe Rd Travelers Rest SC
$287 nightly
The price is $316 total per night from Mar 30 to Mar 31
$316 total
Mar 30 - Mar 31
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Barbecue grills are provided for your convenience.
10/10 Exceptional! (17 reviews)
The room was so spacious, clean, and peaceful! If you are stopping in SC, near Travelers Rest, I highly recommend staying here. I was on a work trip and this place felt like a little hide away to get the rest I needed!

Reviewed on Feb 25, 2026

Opens in a new windowThe Station by Compo Hotels
Hotel Domestique

Hotel Domestique

4 out of 5
10 Road of Vines Travelers Rest SC
$419 nightly
The price is $461 total per night from Mar 19 to Mar 20
$461 total
Mar 19 - Mar 20
Total with taxes and fees
This hotel features a restaurant, an outdoor tennis court, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like cooked-to-order breakfast and ...
Opens in a new windowHotel Domestique
Landing Apartments Greer - Sugar Creek

Landing Apartments Greer - Sugar Creek

4 out of 5
3000 Daventry Cir Greer SC
This apartment features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self ...
Opens in a new windowLanding Apartments Greer - Sugar Creek
Doubletree By Hilton Greenville Airport

Doubletree By Hilton Greenville Airport

4 out of 5
125 The Parkway Greer SC
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $143 total per night from Apr 2 to Apr 3
$143 total
Apr 2 - Apr 3
Total with taxes and fees
A 24-hour gym is available at this hotel. Take advantage of the free self parking.
Opens in a new windowDoubletree By Hilton Greenville Airport
Landing Apartments - Lyman

Landing Apartments - Lyman

4 out of 5
610 Universal Drive Lyman SC
This aparthotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Opens in a new windowLanding Apartments - Lyman
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4 Star Hotels Greenville - Spartanburg

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Greenville - Spartanburg 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Greenville - Spartanburg will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Greenville - Spartanburg, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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