Explore top 2025 4 Star Hotels in Downtown Syracuse
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Top Downtown Syracuse 4 Star hotels

Marriott Syracuse Downtown
100 East Onondaga Street, Syracuse, NY
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $148 total per night from Oct 5 to Oct 6
$148 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.4/10 Very Good! (1,014 reviews)
"We stayed here prior to my son taking an exam at facility for his medical license. The room was very clean, front desk young man was very courteous. He even gave us a free coupon for breakfast for two. We ate at eleven waters for dinner as well. Wow definitely recommend eleven waters. It was so delicious. ..."
Reviewed on Sep 17, 2025

DoubleTree by Hilton Hotel Syracuse
6301 Route 298, East Syracuse, NY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Oct 5 to Oct 6
$158 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free WiFi, free self parking, and a free airport shuttle. ...
8.2/10 Very Good! (1,013 reviews)
"Clean, quiet room, excellent dinner"
Reviewed on Sep 21, 2025

The Brewster Inn
6 Ledyard Avenue, Cazenovia, NY
Fully refundableReserve now, pay when you stay
$233 nightly
The price is $260 total per night from Sep 28 to Sep 29
$260 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features a restaurant, a bar/lounge, and a beach bar. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference ...
9/10 Wonderful! (315 reviews)
Amazing experience
"Great experience, friendly staff, delicious food, beautiful setting."
Reviewed on Sep 16, 2025

Mirbeau Inn and Spa
851 West Genesee Street, Skaneateles, NY
Fully refundableReserve now, pay when you stay
$490 nightly
The price is $588 total per night from Sep 29 to Sep 30
$588 total
Sep 29 - Sep 30
Total with taxes and fees
A full-service spa, 2 restaurants, and a hot tub are all featured at this smoke-free hotel. Business travelers can take advantage of the business center. Enjoy ...
9.6/10 Exceptional! (209 reviews)
"Perfect place to relax"
Reviewed on Aug 27, 2025

Skaneateles Fields Resort & Spa, Curio Collection By Hilton
1000 Mottville Road, Skaneateles, NY
Fully refundableReserve now, pay when you stay
$373 nightly
The price is $448 total per night from Oct 14 to Oct 15
$448 total
Oct 14 - Oct 15
Total with taxes and fees
A sauna is featured at this hotel, along with a terrace and a garden. Dry cleaning is provided and the front desk is staffed around-the-clock.

The Bond 1835
2498 E Lake Rd, Skaneateles, NY
$311 nightly
The price is $357 total per night from Sep 30 to Oct 1
$357 total
Sep 30 - Oct 1
Total with taxes and fees
This bed & breakfast doesn't skimp on freebies - guests receive free WiFi and free self parking. If you want to take your pet along, this pet-friendly property ...
9.8/10 Exceptional! (153 reviews)
"The ladies are so personable. They helped us with our luggage because the suite was upstairs. The room was fantastic. There is a game table and we really enjoyed that. What a great value. I loved visiting with them and the guests."
Reviewed on Aug 19, 2025

Comfort Inn & Suites Airport
6701 Buckley Rd, I-90 & I-81, North Syracuse, NY
This inn features an indoor pool, a 24-hour gym, and a restaurant. Families will appreciate the arcade/game room and onsite laundry facilities. Enjoy the hot ...
Worse Hotel Ever
"When I first got there the woman at the front desk was VERY rude with an attitude. It was dark all the way to finding your room. First thing I wanted was to take a nice hot shower after a day at the beach. Let it run for SEVERAL+ minutes and water was ice cold and didn’t even get warm. On our way ..."
Reviewed on Jul 2, 2020
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Recent Downtown Syracuse hotel reviews by fellow wanderers

Best Western Syracuse Downtown Hotel and Suites
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"The hotel had a quick easy check in. It was walkable to many places and the neighborhood felt safe for where it was. "
A verified traveler stayed at Best Western Syracuse Downtown Hotel and Suites
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