Find and compare 3 Star hotels in Defiance
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Defiance 3 Star hotels
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $136 total per night from Jun 1 to Jun 2
$136 total
Jun 1 - Jun 2
Total with taxes and fees
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $103 total per night from May 25 to May 26
$103 total
May 25 - May 26
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
8/10 Very Good! (1,290 reviews)
"Property very clean. Hotel staff pleasant and attentive. Nice, hot breakfast."
Reviewed on May 19, 2026
La Quinta Inn & Suites by Wyndham St. Louis Westport
11805 Lackland Rd Maryland Heights MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $108 total per night from May 31 to Jun 1
$108 total
May 31 - Jun 1
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
7.2/10 Good! (1,127 reviews)
"parking lot was full. I was not sure if the lot to the side was part of the hotel, as it was not marked in anyway nor did the staff alert me to the face that is was extra parking space. I was only told that in no way was I to use the parking area of the place next door."
Reviewed on May 19, 2026
Crowne Plaza St. Louis Airport by IHG
11228 Lone Eagle Dr Bridgeton MO
Fully refundable
$143 nightly
The price is $169 total per night from May 25 to May 26
$169 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8/10 Very Good! (1,005 reviews)
"The water"
Reviewed on May 16, 2026
Drury Inn & Suites St. Louis St. Peters
170 Mid Rivers Mall Circle St. Peters MO
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $126 total per night from May 24 to May 25
$126 total
May 24 - May 25
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
9.4/10 Exceptional! (1,010 reviews)
"Breakfast was one of the best we have had. Great variety, freshly prepared and hot. All the staff were wonderful."
Reviewed on May 19, 2026
The Wildwood Hotel
2801 Fountain Pl Wildwood MO
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $107 total per night from May 25 to May 26
$107 total
May 25 - May 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
9.2/10 Wonderful! (1,644 reviews)
"Nice property in the St. Louis area! Very clean and luxurious feel to it. Very safe area as it is up in the mountains and away from the city, police department is even next door. Everything is in walking distance. Our room had a very comfortable king size bed, a couch, nice chair with foot stool, ..."
Reviewed on May 17, 2026
Wingate by Wyndham St. Louis/Fenton Route 66
1100 S Highway Dr Fenton MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $98 total per night from May 24 to May 25
$98 total
May 24 - May 25
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7.8/10 Good! (1,228 reviews)
"Reception staff was very helpful."
Reviewed on May 19, 2026
Drury Inn & Suites Southwest St. Louis
5 Lambert Drury Place (I-44 & 141) Valley Park MO
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $137 total per night from May 31 to Jun 1
$137 total
May 31 - Jun 1
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.6/10 Exceptional! (1,025 reviews)
"Staff were great!"
Reviewed on May 19, 2026
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
13639 Riverport Dr Maryland Heights MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $117 total per night from May 25 to May 26
$117 total
May 25 - May 26
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
7.6/10 Good! (1,000 reviews)
"Well worth the money."
Reviewed on May 18, 2026
Drury Plaza Hotel St. Louis St. Charles
380 Mulholland Drive St. Charles MO
Fully refundableReserve now, pay when you stay
$145 nightly
The price is $168 total per night from May 24 to May 25
$168 total
May 24 - May 25
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
9.6/10 Exceptional! (1,000 reviews)
"Room was spotless. Bathroom was the cleanest hotel bathroom I’ve ever had. This hotel is close to the highway but there was 0 highway noise from our room. We will definitely be making this our go to hotel when we come back to St Charles."
Reviewed on May 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
3 Star Hotels Defiance
Maybe you’ve got to travel for work, or perhaps you’re finally ready to book that much-deserved vacation—regardless, it’s time for you to get on a plane and you’re going to make the most of it. You’ve traveled enough to know how important a comfy bed and room service can be, so booking a hotel with all the amenities you need is a priority.
You can find 3 star hotels in Defiance that keep you close to all the great sightseeing and activities around the area, or even book a place that’s a bit more secluded, if that’s what you prefer. No matter what you’re looking for—whether you’re all about the location or are invested in on-site perks--Travelocity will help you find the accommodation that works best for you.
When it comes to options, you’ll have them. The Defiance 3 star hotels give you plenty of choices as far as access to the best areas, and many also offer a breakfast buffet, as well as plenty of other amenities like high-speed Wi-Fi and an on-site pool or spa.
Whatever you’re looking for on your next getaway, browse Travelocity’s big selection of hotels to ensure you get the best possible deal. Book one of the best 3 star hotels in Defiance today!
Recent Defiance hotel reviews by fellow wanderers
Ameristar Casino Resort and Spa
4 out of 5
Posted 6 hours ago
Travelocity Verified Review
"The room was very spacious and the bathroom was also. One of our tv remotes didnʻt work. I wish there was on site laundry and I wish the pool was kid friendly on the weekend at least during the daytime hours, however I understand it is a Casino gaming hotel but I think that would be a great adjustment. I was surprised there werenʻt more on site restaurants available, and I also wish we had access to all the restaurants because the one we really wanted to try and made reservations for before realizing it was inside the casino. The front desk staff was always amazing and very sweet and helpful! Would definitely stay here again, very convenient location to everything we had planned on this trip!"
A verified traveler stayed at Ameristar Casino Resort and Spa
