Find and compare 3 Star hotels in Cape Girardeau

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Top Cape Girardeau 3 Star hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $112 total per night from Feb 22 to Feb 23
$112 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.6/10 Exceptional! (1,003 reviews)
Very clean and the staff are very friendly.

Reviewed on Feb 11, 2026

Opens in a new windowDrury Plaza Hotel Cape Girardeau Conference Center
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $91 total per night from Feb 17 to Feb 18
$91 total
Feb 17 - Feb 18
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
8.8/10 Excellent! (702 reviews)
Room was amazing and clean! The hotel was so quiet!

Reviewed on Feb 9, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St. Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $142 total per night from Feb 26 to Feb 27
$142 total
Feb 26 - Feb 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.4/10 Exceptional! (488 reviews)
Such a pretty hotel and the room was amazing!

Reviewed on Feb 8, 2026

Opens in a new windowCourtyard by Marriott Cape Girardeau Downtown
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $101 total per night from Feb 22 to Feb 23
$101 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
9.4/10 Exceptional! (1,000 reviews)
The staff was ver accommodating love the remodel stayed 4 days could have stayed 4 more. staff is always heplful and friendly 5 *****. One issue. Its been 10 since i checked out, have not got the $50 deposit bk into my account. Thank You I will be coming bk soon

Reviewed on Feb 11, 2026

Opens in a new windowDrury Inn & Suites Cape Girardeau
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $84 total per night from Feb 22 to Feb 23
$84 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
9.6/10 Exceptional! (1,001 reviews)
5:30 meal and breakfast were great. Clean rooms. Great stay.

Reviewed on Feb 12, 2026

Opens in a new windowDrury Inn & Suites Jackson MO
EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

3 out of 5
301 1st St Marble Hill MO
$117 nightly
The price is $127 total per night from Mar 2 to Mar 3
$127 total
Mar 2 - Mar 3
Total with taxes and fees
The hotel doesn't skimp on freebies - guests receive free continental breakfast and free self parking. If you want to take your pet along, this pet-friendly ...
9.6/10 Exceptional! (84 reviews)
Clean rooms, great value.

Reviewed on Nov 28, 2025

Opens in a new windowEC Reed's Mercantile and Hotel
Makanda Inn

Makanda Inn

3.5 out of 5
855 Old Lower Cobden Road Makanda IL
$288 nightly
The price is $319 total per night from Feb 22 to Feb 23
$319 total
Feb 22 - Feb 23
Total with taxes and fees
A restaurant and a bar/lounge are featured at this bed & breakfast. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
10/10 Exceptional! (35 reviews)
This is such a warm and inviting place to stay! The caretaker was very kind and available for any questions or needs, and made a great breakfast! It is clean and well-stocked with anything you might need. Will definitely be back!

Reviewed on Jan 21, 2026

Opens in a new windowMakanda Inn
Cozy Anna Home Near Southern Illinois Attractions!

Cozy Anna Home Near Southern Illinois Attractions!

3 out of 5
Anna IL
Free WiFi in public areas is available at this cottage. Take advantage of the free self parking.
Good communication with the owners. Nice perks such as coffee, tea, and hygiene items.

Reviewed on Feb 3, 2025

Opens in a new windowCozy Anna Home Near Southern Illinois Attractions!
Oak Grove Cabins

Oak Grove Cabins

3 out of 5
413 Oak Grove Rd Makanda IL
A hot tub is featured at this cabin, along with barbecue grills. Take advantage of the free self parking.
Awsome cabin and really private. Lots of nice touches. Great coverage for our Verizon hotspot.

Reviewed on Feb 21, 2019

Opens in a new windowOak Grove Cabins
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3 Star Hotels Cape Girardeau

Maybe you’ve got to travel for work, or perhaps you’re finally ready to book that much-deserved vacation—regardless, it’s time for you to get on a plane and you’re going to make the most of it. You’ve traveled enough to know how important a comfy bed and room service can be, so booking a hotel with all the amenities you need is a priority.

You can find 3 star hotels in Cape Girardeau that keep you close to all the great sightseeing and activities around the area, or even book a place that’s a bit more secluded, if that’s what you prefer. No matter what you’re looking for—whether you’re all about the location or are invested in on-site perks--Travelocity will help you find the accommodation that works best for you.

When it comes to options, you’ll have them. The Cape Girardeau 3 star hotels give you plenty of choices as far as access to the best areas, and many also offer a breakfast buffet, as well as plenty of other amenities like high-speed Wi-Fi and an on-site pool or spa.

Whatever you’re looking for on your next getaway, browse Travelocity’s big selection of hotels to ensure you get the best possible deal. Book one of the best 3 star hotels in Cape Girardeau today!

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