Find and compare 3 Star hotels in Cape Girardeau

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Top Cape Girardeau 3 Star hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $113 total per night from Apr 12 to Apr 13
$113 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.6/10 Exceptional! (1,011 reviews)
Had a great experience here. Staff was extremely friendly and interactive. Great location near restaurants, shopping and the mall.

Reviewed on Apr 6, 2026

Opens in a new windowDrury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Apr 12 to Apr 13
$102 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
9.4/10 Exceptional! (1,006 reviews)
Wonderful. I will definitely stay here again.

Reviewed on Apr 3, 2026

Opens in a new windowDrury Inn & Suites Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $96 total per night from Apr 9 to Apr 10
$96 total
Apr 9 - Apr 10
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
9/10 Wonderful! (737 reviews)
Yes the Church of Jesus Christ is just up the road about 3 miles 😊

Reviewed on Apr 6, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $81 total per night from Apr 12 to Apr 13
$81 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
9.6/10 Exceptional! (1,004 reviews)
Not very nice staff. Clean place

Reviewed on Apr 6, 2026

Opens in a new windowDrury Inn & Suites Jackson MO
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St. Cape Girardeau MO
$125 nightly
The price is $142 total per night from Apr 19 to Apr 20
$142 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.6/10 Exceptional! (500 reviews)
Great place!

Reviewed on Apr 1, 2026

Opens in a new windowCourtyard by Marriott Cape Girardeau Downtown
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

3 out of 5
433 CAPE WEST CROSSINGS Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Apr 16 to Apr 17
$105 total
Apr 16 - Apr 17
Total with taxes and fees
An indoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi in ...
9.4/10 Exceptional! (172 reviews)
This hotel is newer and very well kept. It smells nice and clean when you walk in! It’s close to the interstate- so you can hear the traffic a bit- but I just turned the fan on for white noise. The staff is very friendly, they have a WONDERFUL breakfast area with lots of choices! The staff person ...

Reviewed on Apr 5, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Cape Girardeau
EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

3 out of 5
301 1st St Marble Hill MO
$88 nightly
The price is $96 total per night from Apr 12 to Apr 13
$96 total
Apr 12 - Apr 13
Total with taxes and fees
The hotel doesn't skimp on freebies - guests receive free continental breakfast and free self parking. If you want to take your pet along, this pet-friendly ...
9.6/10 Exceptional! (85 reviews)
Parking was easy. The staff were super friendly and helpful. Room was nice and comfortable. I definetely recommend staying here if you are in this area.

Reviewed on Mar 22, 2026

Opens in a new windowEC Reed's Mercantile and Hotel
Makanda Inn

Makanda Inn

3.5 out of 5
855 Old Lower Cobden Road Makanda IL
$255 nightly
The price is $282 total per night from Apr 14 to Apr 15
$282 total
Apr 14 - Apr 15
Total with taxes and fees
A restaurant and a bar/lounge are featured at this bed & breakfast. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
10/10 Exceptional! (36 reviews)
Friendly staff that met our needs.

Reviewed on Apr 3, 2026

Opens in a new windowMakanda Inn
Cozy Anna Home Near Southern Illinois Attractions!

Cozy Anna Home Near Southern Illinois Attractions!

3 out of 5
Anna IL
Free WiFi in public areas is available at this cottage. Take advantage of the free self parking.
10/10 Exceptional! (1 review)
Good communication with the owners. Nice perks such as coffee, tea, and hygiene items.

Reviewed on Feb 3, 2025

Opens in a new windowCozy Anna Home Near Southern Illinois Attractions!
Oak Grove Cabins

Oak Grove Cabins

3 out of 5
413 Oak Grove Rd Makanda IL
A hot tub is featured at this cabin, along with barbecue grills. Take advantage of the free self parking.
10/10 Exceptional! (5 reviews)
Awsome cabin and really private. Lots of nice touches. Great coverage for our Verizon hotspot.

Reviewed on Feb 21, 2019

Opens in a new windowOak Grove Cabins
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

3 Star Hotels Cape Girardeau

Maybe you’ve got to travel for work, or perhaps you’re finally ready to book that much-deserved vacation—regardless, it’s time for you to get on a plane and you’re going to make the most of it. You’ve traveled enough to know how important a comfy bed and room service can be, so booking a hotel with all the amenities you need is a priority.

You can find 3 star hotels in Cape Girardeau that keep you close to all the great sightseeing and activities around the area, or even book a place that’s a bit more secluded, if that’s what you prefer. No matter what you’re looking for—whether you’re all about the location or are invested in on-site perks--Travelocity will help you find the accommodation that works best for you.

When it comes to options, you’ll have them. The Cape Girardeau 3 star hotels give you plenty of choices as far as access to the best areas, and many also offer a breakfast buffet, as well as plenty of other amenities like high-speed Wi-Fi and an on-site pool or spa.

Whatever you’re looking for on your next getaway, browse Travelocity’s big selection of hotels to ensure you get the best possible deal. Book one of the best 3 star hotels in Cape Girardeau today!

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