Find and compare 3 Star hotels in Cape Girardeau

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Top Cape Girardeau 3 Star hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Dec 1 to Dec 2
$102 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.4/10 Exceptional! (1,004 reviews)
The room was clean and comfy. The staf was friendly, courteous and efficient. Many thanks!

Reviewed on Nov 5, 2025

Opens in a new windowDrury Plaza Hotel Cape Girardeau Conference Center
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $91 total per night from Nov 16 to Nov 17
$91 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
8.8/10 Excellent! (648 reviews)
Thanks

Reviewed on Nov 9, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St., Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $131 total per night from Nov 24 to Nov 25
$131 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.4/10 Exceptional! (459 reviews)
Very clean and such kind staff!

Reviewed on Nov 9, 2025

Opens in a new windowCourtyard by Marriott Cape Girardeau Downtown
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Nov 23 to Nov 24
$102 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
9.4/10 Exceptional! (1,002 reviews)
Clean and friendly staff!!!

Reviewed on Nov 9, 2025

Opens in a new windowDrury Inn & Suites Cape Girardeau
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane, Jackson, MO
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $93 total per night from Nov 16 to Nov 17
$93 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
9.6/10 Exceptional! (1,005 reviews)
One of the cleanest hotel we’ve stayed at. Extremely friendly personnel, starting at the check in counter, to the employees maintaining the breakfast buffet. When traveling, if there’s a Drury Inn & Suites, we’ll be booking with them every time.

Reviewed on Nov 7, 2025

Opens in a new windowDrury Inn & Suites Jackson MO
EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

3 out of 5
301 1st St Marble Hill MO
$117 nightly
The price is $127 total per night from Nov 17 to Nov 18
$127 total
Nov 17 - Nov 18
Total with taxes and fees
A restaurant, free self parking, and a snack bar/deli are among this hotel's amenities. Enjoy the free continental breakfast each morning. Express check-in and ...
9.6/10 Exceptional! (82 reviews)
Cute room, great food, fun soda fountain and friendly owners! Will return!

Reviewed on Nov 11, 2025

Opens in a new windowEC Reed's Mercantile and Hotel
Makanda Inn

Makanda Inn

3.5 out of 5
855 Old Lower Cobden Road, Makanda, IL
$285 nightly
The price is $315 total per night from Nov 16 to Nov 17
$315 total
Nov 16 - Nov 17
Total with taxes and fees
A restaurant and a bar/lounge are featured at this bed & breakfast. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
10/10 Exceptional! (33 reviews)
Peaceful and relaxing.

Reviewed on May 20, 2025

Opens in a new windowMakanda Inn
Cozy Anna Home Near Southern Illinois Attractions!

Cozy Anna Home Near Southern Illinois Attractions!

3 out of 5
Anna
Free WiFi in public areas is available at this cottage. Take advantage of the free self parking.
Good communication with the owners. Nice perks such as coffee, tea, and hygiene items.

Reviewed on Feb 3, 2025

Opens in a new windowCozy Anna Home Near Southern Illinois Attractions!
Oak Grove Cabins

Oak Grove Cabins

3 out of 5
413 Oak Grove Rd, Makanda, IL
A hot tub is featured at this cabin, along with barbecue grills. Take advantage of the free self parking.
Awsome cabin and really private. Lots of nice touches. Great coverage for our Verizon hotspot.

Reviewed on Feb 21, 2019

Opens in a new windowOak Grove Cabins
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

3 Star Hotels Cape Girardeau

Maybe you’ve got to travel for work, or perhaps you’re finally ready to book that much-deserved vacation—regardless, it’s time for you to get on a plane and you’re going to make the most of it. You’ve traveled enough to know how important a comfy bed and room service can be, so booking a hotel with all the amenities you need is a priority.

You can find 3 star hotels in Cape Girardeau that keep you close to all the great sightseeing and activities around the area, or even book a place that’s a bit more secluded, if that’s what you prefer. No matter what you’re looking for—whether you’re all about the location or are invested in on-site perks--Travelocity will help you find the accommodation that works best for you.

When it comes to options, you’ll have them. The Cape Girardeau 3 star hotels give you plenty of choices as far as access to the best areas, and many also offer a breakfast buffet, as well as plenty of other amenities like high-speed Wi-Fi and an on-site pool or spa.

Whatever you’re looking for on your next getaway, browse Travelocity’s big selection of hotels to ensure you get the best possible deal. Book one of the best 3 star hotels in Cape Girardeau today!

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