Southern Illinois Vacation Packages 2025/2026 from $320

Southern Illinois flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

DoubleTree by Hilton St. Louis Forest Park

Central West End

$320

per person

Nov 6 - Nov 9

found 24 hours ago

Roundtrip flight included

Denver (DEN) to St. Louis (STL)

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Self parking, a grocery/convenience store, and a lobby fireplace are also offered.

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center

Save 100% on your flight

$373

per person

Nov 6 - Nov 9

found 24 hours ago

Roundtrip flight included

Denver (DEN) to St. Louis (STL)

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. There's a rooftop terrace on site, and a 24-hour front desk and a snack bar/deli are also provided.

Home2 Suites by Hilton St. Louis/Forest Park

The Grove

Save 100% on your flight

$415

per person

Nov 6 - Nov 9

found 24 hours ago

Roundtrip flight included

Denver (DEN) to St. Louis (STL)

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free perks include buffet breakfast, free self parking, and an area shuttle.

Hilton Garden Inn St. Louis/O'Fallon MO

$538

per person

Nov 7 - Nov 11

found 6 hours ago

Roundtrip flight included

Oklahoma City (OKC) to St. Louis (STL)

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free self parking and free WiFi. A business center, a grocery/convenience store, and a lobby fireplace are also on offer.

Hampton Inn By Hilton St Louis Airport

Woodson Terrace

$351

per person

Nov 6 - Nov 9

found 24 hours ago

Roundtrip flight included

Denver (DEN) to St. Louis (STL)

Self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate freebies like continental breakfast, WiFi in public areas, and a roundtrip airport shuttle. Express check-in and express check-out are also provided.

Top Southern Illinois hotels deals

Drury Plaza Hotel Mt. Vernon

145 North 44th Street , Mount Vernon, IL

Free Cancellation

Reserve now, pay when you stay

$106 total

per night

Oct 5 - Oct 6

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Drury Inn & Suites St. Louis Fairview Heights

12 Ludwig Dr, Fairview Heights, IL

Free Cancellation

Reserve now, pay when you stay

$106 total

per night

Oct 5 - Oct 6

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr, O'Fallon, IL

Free Cancellation

Reserve now, pay when you stay

$59 total

per night

Oct 5 - Oct 6

This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.

Pool

Breakfast included

Best Western Plus Pontoon Beach

4 Regency Pkwy, Granite City, IL

Free Cancellation

Reserve now, pay when you stay

$100 total

per night

Oct 2 - Oct 3

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

Red Lion Inn & Suites Pontoon Beach

1240 E Chain Of Rocks Rd, Granite City, IL

Free Cancellation

Reserve now, pay when you stay

$71 total

per night

Oct 4 - Oct 5

This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour front desk can provide around-the-clock assistance.

Breakfast included

Pet friendly

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

136 Regency Park, O'Fallon, IL

Free Cancellation

Reserve now, pay when you stay

$82 total

per night

Oct 26 - Oct 27

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Southern Illinois University

4.5/5(173 reviews)

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

Garden of the Gods Recreation Area

5/5(6 reviews)

See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.

Superman Statue

4.5/5(104 reviews)

Superman fans will love getting a photograph taken in front of this giant statue of the Man of Steel himself, dressed in his iconic red-and-blue guise.

Frequently asked questions

How much are vacation packages to Southern Illinois?

Your travel fantasies can become a reality in Southern Illinois for as little as $320. Our package deals include flights and hotels, so booking your trip will be a piece of cake. The only thing you'll need to worry about is what amazing attraction you'll head to first.

Where can I get the best vacation package deals for Southern Illinois?

With at least 400 air carriers and 1,000,000 properties around the world, it's tough to beat Travelocity. Take advantage of our comprehensive range and grab an affordable Southern Illinois vacation package. Doesn't it feel amazing when travel is that easy?

Why should I purchase my Southern Illinois vacation package via Travelocity?

The three S's — savings, support and a stress-free booking — are just the beginning. Enjoy a fulfilling travel experience knowing you can rely on our expert team of customer support professionals 24/7. With the Travelocity Price Match Guarantee, you can rest easy knowing you're getting the best deal available.

Can I save on my Southern Illinois car rental if I bundle it with a hotel or flight?

You can with our Southern Illinois vacation packages. With one of these, there are lots of ways to stretch your budget further. Combine any two or more car, flight, hotel and tour bookings and watch the savings start to pile up. With your own set of wheels, all the landmarks around Southern Illinois are just a road trip away.

Which airport is best for Southern Illinois?

Williamson County Regional Airport (MWA) is the main airport that offers flights in and out of Southern Illinois.

What is there to do in Southern Illinois?

Southern Illinois boasts hidden gems at every turn, however make sure you see Shawnee National Forest and Southern Illinois University while you're in town. These two attractions are popular with visitors.