Southern Illinois Vacation Packages 2026 from $414

Southern Illinois flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

HoteLumiere at the Arch Hotel & Casino - A Caesars Rewards Destination

Downtown St. Louis

$414

per person

Oct 18 - Oct 21

found 1 day ago

Roundtrip flight included

Chicago (ORD) to St. Louis (STL)

This hotel features a casino and 4 restaurants. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.

The Wildwood Hotel

Save 100% on your flight

$688

per person

Nov 5 - Nov 8

found 15 hours ago

Roundtrip non-stop flight included

Baltimore (BWI) to St. Louis (STL)

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.

Hermann Grain Bins BNB

$1,478

per person

Nov 22 - Nov 28

found 16 hours ago

Roundtrip flight included

Los Angeles (LAX) to St. Louis (STL)

This bed & breakfast features free WiFi in public areas, barbecue grills, and free self parking. Enjoy the free full breakfast each morning. A garden and a picnic area are also provided.

The Cheshire

$694

per person

Nov 5 - Nov 8

found 17 hours ago

Roundtrip non-stop flight included

Baltimore (BWI) to St. Louis (STL)

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free English breakfast each morning.

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Riverport

$494

per person

Nov 5 - Nov 8

found 16 hours ago

Roundtrip non-stop flight included

Baltimore (BWI) to St. Louis (STL)

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

Top Southern Illinois hotels deals

Drury Inn & Suites St. Louis Fairview Heights

12 Ludwig Dr Fairview Heights IL

Free Cancellation

Reserve now, pay when you stay

$90 nightly

$102 total

Sep 20 - Sep 21

Total with taxes and fees

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Drury Plaza Hotel Mt. Vernon

145 North 44th Street Mount Vernon IL

Free Cancellation

Reserve now, pay when you stay

$111 nightly

$125 total

Sep 13 - Sep 14

Total with taxes and fees

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL

Free Cancellation

Reserve now, pay when you stay

$54 nightly

$63 total

Sep 21 - Sep 22

Total with taxes and fees

This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.

Pool

Breakfast included

Quality Inn O'Fallon - St. Louis - Shiloh

1409 W US 50 O'Fallon IL

Free Cancellation

$67 nightly

$77 total

Sep 13 - Sep 14

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour business center. There's an indoor pool on site, and laundry facilities and free newspapers are also offered.

Pool

Breakfast included

Drury Inn & Suites St. Louis O'Fallon, IL

1118 Central Park Drive O'Fallon IL

Free Cancellation

Reserve now, pay when you stay

$106 nightly

$123 total

Sep 27 - Sep 28

Total with taxes and fees

Pool

Hot Tub

Comfort Inn Edwardsville - St. Louis

3080 S State Route 157 Edwardsville IL

Free Cancellation

$100 nightly

$115 total

Sep 23 - Sep 24

Total with taxes and fees

This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A 24-hour business center, a snack bar/deli, and dry cleaning are also on offer.

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

9.8/10 (63 reviews)

See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.

See properties

Frequently asked questions

How much are vacation packages to Southern Illinois?

Your travel fantasies can become a reality in Southern Illinois for as little as $414. Our package deals include flights and hotels, so booking your trip will be a piece of cake. The only thing you'll need to worry about is what amazing attraction you'll head to first.

Where can I get the best vacation package deals for Southern Illinois?

With at least 400 air carriers and 1,000,000 properties around the world, it's tough to beat Travelocity. Take advantage of our comprehensive range and grab an affordable Southern Illinois vacation package. Doesn't it feel amazing when travel is that easy?

Why should I purchase my Southern Illinois vacation package via Travelocity?

The three S's — savings, support and a stress-free booking — are just the beginning. Enjoy a fulfilling travel experience knowing you can rely on our expert team of customer support professionals 24/7. With the Travelocity Price Match Guarantee, you can rest easy knowing you're getting the best deal available.

Can I save on my Southern Illinois car rental if I bundle it with a hotel or flight?

You can with our Southern Illinois vacation packages. With one of these, there are lots of ways to stretch your budget further. Combine any two or more car, flight, hotel and tour bookings and watch the savings start to pile up. With your own set of wheels, all the landmarks around Southern Illinois are just a road trip away.

Which airport is best for Southern Illinois?

Williamson County Regional Airport (MWA) is the main airport that offers flights in and out of Southern Illinois.

What is there to do in Southern Illinois?

Southern Illinois boasts hidden gems at every turn, however make sure you see Shawnee National Forest and Southern Illinois University while you're in town. These two attractions are popular with visitors.