Book Hotels in Southeastern Indiana

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Southeastern Indiana hotels

Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

3 out of 5
4900 Water Tower Road Jeffersonville IN
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $120 total per night from Dec 27 to Dec 28
$120 total
Dec 27 - Dec 28
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The room was spotless and the staff was great.

Reviewed on Dec 15, 2025

Opens in a new windowHilton Garden Inn Jeffersonville Louisville North
TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North

3 out of 5
301 West Maple Street Jeffersonville IN
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $121 total per night from Jan 1 to Jan 2
$121 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Clean rooms lots of Space and the beds were comfortable very helpful staff and a Good breakfast

Reviewed on Dec 20, 2025

Opens in a new windowTownePlace Suites by Marriott Louisville North
Comfort Inn & Suites Clarksville - Louisville North

Comfort Inn & Suites Clarksville - Louisville North

2.5 out of 5
1485 Broadway St Clarksville IN
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Jan 16 to Jan 17
$105 total
Jan 16 - Jan 17, 2026
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Room is beautiful! Excellent condition and clean! Staff is very friendly and accommodating! I recommend this Comfort Inn if you are looking in this area.

Reviewed on Dec 20, 2025

Opens in a new windowComfort Inn & Suites Clarksville - Louisville North
Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

2.5 out of 5
411 W Spring Street New Albany IN
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $107 total per night from Jan 5 to Jan 6
$107 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Easy check in

Reviewed on Dec 19, 2025

Opens in a new windowHampton Inn New Albany Louisville West
Home2 Suites by Hilton Clarksville Louisville North

Home2 Suites by Hilton Clarksville Louisville North

3 out of 5
1624 Leisure Way Clarksville IN
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $132 total per night from Jan 12 to Jan 13
$132 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business ...
Clea

Reviewed on Dec 15, 2025

Opens in a new windowHome2 Suites by Hilton Clarksville Louisville North
Sheraton Louisville Riverside by Marriott

Sheraton Louisville Riverside by Marriott

3.5 out of 5
700 West Riverside Drive Jeffersonville IN
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $95 total per night from Jan 4 to Jan 5
$95 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
The hotel's indoor pool, 24-hour gym, and 3 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center ...
Staff was extremely friendly, helpful, and just exceptional all around. From check in to leaving the building we were greeted with kindness. Tim in club level was so kind and funny! I will definitely be staying here again, instead of the Galt House.

Reviewed on Dec 16, 2025

Opens in a new windowSheraton Louisville Riverside by Marriott
Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North

2.5 out of 5
360 Triangle Dr Sellersburg IN
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $82 total per night from Dec 25 to Dec 26
$82 total
Dec 25 - Dec 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies like full ...
Manager Dilip Patel’s hospitality was excellent and made special accommodations for myself and elderly mother. It was the cleanest hotel I’ve ever stayed at! All staff were friendly and they seemed happy to be working there.

Reviewed on Dec 18, 2025

Opens in a new windowRamada by Wyndham Sellersburg/Louisville North
Best Western Green Tree Inn

Best Western Green Tree Inn

2.5 out of 5
1425 Broadway Street Clarksville IN
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $81 total per night from Dec 29 to Dec 30
$81 total
Dec 29 - Dec 30
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like full breakfast and WiFi in public areas. ...
Yes

Reviewed on Dec 19, 2025

Opens in a new windowBest Western Green Tree Inn
Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
Fully refundable
$60 nightly
The price is $67 total per night from Dec 29 to Dec 30
$67 total
Dec 29 - Dec 30
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
ROOMS WERE CLEAN!!!

Reviewed on Dec 17, 2025

Opens in a new windowRadisson Hotel Louisville North
Don't see what you're looking for?
See all available properties in Southeastern Indiana
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southeastern Indiana hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Southeastern Indiana hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity