Book Hotels in Six Mile, SC
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Top Six Mile hotels

Wooded Cottage - 3 Mi to Clemson University
Clemson SC
Free WiFi in public areas is available at this cottage.

The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $185 total per night from Dec 7 to Dec 8
$185 total
Dec 7 - Dec 8
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
BEST hotel in all of Clemson!
Reviewed on Nov 15, 2025

Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more
Six Mile SC
This vacation home featured laundry facilities and barbecue grills.
The hosts were amazing! So responsive and helpful. Great house.
Reviewed on Nov 11, 2025

Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Nov 23 to Nov 24
$135 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
Staff was warm and helpful. The room itself was amazing, clean, well equipped. Excellent location
Reviewed on Nov 18, 2025

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $93 total per night from Nov 24 to Nov 25
$93 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Clean and Friendly!
Reviewed on Nov 14, 2025

Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $99 total per night from Nov 25 to Nov 26
$99 total
Nov 25 - Nov 26
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Room was clean. The hotel was quiet for a college town and a night game. Staff was polite and friendly.
Reviewed on Nov 14, 2025

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $89 total per night from Nov 30 to Dec 1
$89 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Clean room w fridge and microwave Comfy bed
Reviewed on Nov 15, 2025

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Nov 23 to Nov 24
$70 total
Nov 23 - Nov 24
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Clean rooms, safe and clean property, top notch customer service the owner and front desk are all wonderful from start to finish. You wont regret a second here.
Reviewed on Nov 17, 2025

Quality Inn Clemson near University
3430 Clemson Blvd Anderson SC
Fully refundableReserve now, pay when you stay
$51 nightly
The price is $56 total per night from Nov 30 to Dec 1
$56 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...
Shopping is good nears around
Reviewed on Sep 27, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Six Mile hotel reviews by fellow wanderers

Baymont by Wyndham Anderson Clemson
5 out of 5
Posted 22 hours ago
Travelocity Verified Review
"This time i was put on the good side yes theyre are levels to this hotel apparently. The bad side faces the interstate if you want a good experience make sure they dont put you on the side facing i85"
A verified traveler stayed at Baymont by Wyndham Anderson Clemson
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