Book Hotels in Six Mile, SC
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Top Six Mile hotels

Lake Keowee Lakefront Cove, Private Dock, Deep Water Access, Kayaks & more
Six Mile
This vacation home featured laundry facilities and barbecue grills.
"First, my wife and I are very familiar with Lake Keowee and have owned a home up here & have also rented many lake K properties since the late 90s. This was a short trip for us in Sept. IMO, the months of September and October are the best time to visit this late. The crowds are gone but the water ..."
Reviewed on Sep 22, 2025

Wooded Cottage - 3 Mi to Clemson University
Clemson
Free WiFi in public areas is available at this cottage. Take advantage of the free self parking.

The Shepherd Hotel Downtown Clemson
110 Sloan St, Clemson, SC
Fully refundableReserve now, pay when you stay
$189 nightly
The price is $210 total per night from Sep 29 to Sep 30
$210 total
Sep 29 - Sep 30
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
"Everything! Beautiful, convenient and wonderful staff!"
Reviewed on Sep 24, 2025

Lakeside Lodge Clemson
13500 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Sep 28 to Sep 29
$135 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
"Great place to stay while visiting our Tiger!"
Reviewed on Sep 20, 2025

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $112 total per night from Sep 30 to Oct 1
$112 total
Sep 30 - Oct 1
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Very cool hotel layout, adjacent to good restaurant. Pool is behind hotel and didn't seem to be open - doesn't feel super safe behind the hotel."
Reviewed on Sep 26, 2025

Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $108 total per night from Oct 19 to Oct 20
$108 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Very good value for this hotel considering its location near Clemson's downtown. Comfortable beds."
Reviewed on Sep 15, 2025

Inn @ Clemson
1303 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $103 total per night from Oct 7 to Oct 8
$103 total
Oct 7 - Oct 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Good location"
Reviewed on Sep 20, 2025

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd, Seneca, SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $93 total per night from Oct 5 to Oct 6
$93 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"Convenient"
Reviewed on Sep 21, 2025

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd, Anderson, SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from Sep 29 to Sep 30
$66 total
Sep 29 - Sep 30
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Friendly faces, cozy rooms—couldn’t ask for more Great vibes here! Would happily stay again."
Reviewed on Sep 20, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Six Mile hotel reviews by fellow wanderers

The Shepherd Hotel Downtown Clemson
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Everything! Beautiful, convenient and wonderful staff!"
A verified traveler stayed at The Shepherd Hotel Downtown Clemson
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