Book Hotels in Six Mile, SC

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Top Six Mile hotels

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2 out of 5
299 Outpost Rd Seneca SC
$139 nightly
The price is $153 total per night from Apr 26 to Apr 27
$153 total
Apr 26 - Apr 27
Total with taxes and fees
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
The space was gorgeous! It was clean and well equipped with everything you could possibly need from pots and pans, silverware, cups, plates, snacks and extra toiletries! The hosts were very communicative. Instructions were clear and check in was seamless. I loved how quiet the area was as well. We ...

Reviewed on Apr 21, 2026

Opens in a new windowPostcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $221 total per night from May 10 to May 11
$221 total
May 10 - May 11
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
Beautiful hotel. Great spot downtown. Our room could’ve been cleaner and was a little worn. Staff was mostly college kids who were very attentive and thoughtful.

Reviewed on Apr 22, 2026

Opens in a new windowThe Shepherd Hotel Downtown Clemson
Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more

Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more

Six Mile SC
This vacation home features a garden, laundry facilities, and barbecue grills.
Well stocked, loved the dock and screened in porch!

Reviewed on Apr 13, 2026

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Opens in a new windowLake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
$123 nightly
The price is $135 total per night from Apr 24 to Apr 25
$135 total
Apr 24 - Apr 25
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
great place

Reviewed on Apr 20, 2026

Opens in a new windowLakeside Lodge Clemson
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $117 total per night from Apr 25 to Apr 26
$117 total
Apr 25 - Apr 26
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Helpful front desk

Reviewed on Apr 21, 2026

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Inn @ Clemson

Inn @ Clemson

2.5 out of 5
1303 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $101 total per night from Apr 26 to Apr 27
$101 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Bed was clean but hotel in general is not great. Would not stay here again

Reviewed on Apr 20, 2026

Opens in a new windowInn @ Clemson
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
Fully refundable
$98 nightly
The price is $109 total per night from May 24 to May 25
$109 total
May 24 - May 25
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Large room & bathroom

Reviewed on Apr 20, 2026

Opens in a new windowComfort Inn & Suites Clemson - University Area
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $68 total per night from Apr 26 to Apr 27
$68 total
Apr 26 - Apr 27
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
The room smelled straight up like bleach. Continental breakfast only a rat would love.

Reviewed on Apr 23, 2026

Opens in a new windowDays Inn by Wyndham Anderson
Cabin on Lake Keowee - Dock Slip Included

Cabin on Lake Keowee - Dock Slip Included

Six Mile SC
A hot tub is featured at this cottage, along with laundry facilities and barbecue grills.
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Opens in a new windowCabin on Lake Keowee - Dock Slip Included
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See all available properties in Six Mile
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Where can I find cheap hotels in Six Mile?
At Travelocity you'll find really nice hotels in Six Mile at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Six Mile rather than in Six Mile. We may find you even better rates, too.
How do I find the best Six Mile hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Six Mile then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Six Mile?
The cheapest hotel in Six Mile is $68. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Six Mile?
There are 1,536 hotels in Six Mile on Travelocity.
What are the best hotels in Six Mile?
Six Mile has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Six Mile for you!
When is the best time to visit Six Mile?
If you want the joy of a fun-filled trip in peak season, visit Six Mile during March, July and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as October, November and December.
When is the cheapest time to stay in Six Mile?
Based on historic data is usually the cheapest month to visit Six Mile. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Six Mile?
There are multiple hotels in Six Mile that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Six Mile. We have plenty of kid-friendly hotels in Six Mile to choose from on Travelocity!
Why book a hotel in Six Mile through Travelocity?
Because we have the top hotels in Six Mile! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Six Mile on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Six Mile hotel reviews by fellow wanderers

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
Posted 2 hours ago
Travelocity Verified Review
"The room smelled straight up like bleach. Continental breakfast only a rat would love."
A verified traveler stayed at Days Inn by Wyndham Anderson
Days Inn by Wyndham Anderson

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