Book Hotels in Six Mile, SC
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Six Mile hotels

Wooded Cottage - 3 Mi to Clemson University
Clemson SC
Free WiFi in public areas is available at this cottage.

The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $186 total per night from Dec 7 to Dec 8
$186 total
Dec 7 - Dec 8
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
Staff was great... room spotless... coffee stations conveniently located on each floor.
Reviewed on Nov 25, 2025

Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more
Six Mile SC
This vacation home featured laundry facilities and barbecue grills.
The hosts were amazing! So responsive and helpful. Great house.
Reviewed on Nov 11, 2025

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $103 total per night from Dec 21 to Dec 22
$103 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Clean; good breakfast; kind staff
Reviewed on Nov 23, 2025

Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $104 total per night from Dec 21 to Dec 22
$104 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Ease of checking in
Reviewed on Nov 23, 2025

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $89 total per night from Dec 7 to Dec 8
$89 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Property felt safe
Reviewed on Nov 24, 2025

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Dec 1 to Dec 2
$70 total
Dec 1 - Dec 2
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
I didn't have breakfast but the breakfast area was clean. It looked like they had waffle irons, cereal dispensers, coffee, juice & oatmeal which sounds like a pretty good free breakfast to me.
Reviewed on Nov 25, 2025

Baymont by Wyndham Easley/Greenville
211 Dayton School Rd Easley SC
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Nov 30 to Dec 1
$71 total
Nov 30 - Dec 1
Total with taxes and fees
This motel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Stay was great for the price point. The accessibility shower wand was not the best could have been. Wouldn’t stay up when it was on the holder. Clean room, staff was great, Breakfast was good, and parking was great. Will definitely stay again when in the area.
Reviewed on Nov 25, 2025

Quality Inn Clemson near University
3430 Clemson Blvd Anderson SC
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $55 total per night from Dec 9 to Dec 10
$55 total
Dec 9 - Dec 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...
Shopping is good nears around
Reviewed on Sep 27, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Six Mile hotel reviews by fellow wanderers

The Shepherd Hotel Downtown Clemson
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Staff was great... room spotless... coffee stations conveniently located on each floor."
A verified traveler stayed at The Shepherd Hotel Downtown Clemson
Explore More Ways to Travel with Travelocity
- Hotels near Littlejohn Coliseum
- Hotels near Tri-County Technical College
- Hotels near Southern Wesleyan University
- Hotels near South Carolina Botanical Gardens
- Pendleton Hotels
- Hotels near Memorial Stadium
- Hotels near Ultimate Action Sports
- West Union Hotels
- Seneca Hotels
- Indian Oaks Hotels
- Cabins in Keowee
- Houseboats in Keowee
- Vacation Homes in Keowee
- Hotels near Clemson University
- Hotels near Lake Jocassee
- Hotels near Keowee Key Golf Course
- Salem Hotels
- Hotels near Lake Keowee
- Farmstay in Clemson
- Apartments in Clemson
- B&B in Clemson
- Cabins in Clemson
- Condos in Clemson
- Cottages in Clemson
- Extended Stay Hotels in Clemson
- Boutique Hotels in Clemson
- Golf Resorts & in Clemson
- Hotels with Balconies in Clemson
- Hotels with Bar in Clemson
- Hotels with Hot Tubs in Clemson
- Hotels with an Indoor Pool in Clemson
- Pet Friendly Hotels in Clemson
- Spa Resorts & in Clemson
- Clemson Hotels
- Houseboats in Clemson
- Motels in Clemson
- Vacation Homes in Clemson
- Rv Parks in Clemson
- Sunset Hotels
- Hotels near Foothills Playhouse
- Hotels near Fort Hill
- Hotels near T. Ed Garrison Arena
- Pet Friendly Hotels in Pickens County
- Easley Hotels
- Hotels near Larry W. Abernathy Waterfront Park
- Hotels near Devils Fork State Park
- Farmstay in Liberty
- B&B in Liberty
- Cabins in Liberty
- Extended Stay Hotels in Liberty
- Liberty Hotels
- Motels in Liberty
- Rv Parks in Liberty
- Serenity Bay Hotels
- Farmstay in Pickens
- B&B in Pickens
- Cabins in Pickens
- Cottages in Pickens
- Extended Stay Hotels in Pickens
- Guest Houses in Pickens
- Pet Friendly Hotels in Pickens
- Pickens Hotels
- Lodges in Pickens
- Motels in Pickens
- Vacation Homes in Pickens
- Resorts in Pickens
- Hotels near Keowee-Toxaway State Park
- Apartments in Central
- B&B in Central
- Chalets in Central
- Cottages in Central
- Extended Stay Hotels in Central
- Central Hotels
- Motels in Central
- Hotels near Brooks Center for the Performing Arts
- Normandy Shores Hotels
- Avis Rental Cars in Pickens County
- Hertz Rental Cars in Pickens County
- Car rental Clemson
- Luxury Car Rentals in Clemson
- Van Car Rentals in Clemson
- Car rental Liberty
- Car rentals in Dollar Rent A Car 12 Avenue Adrien Treuille
- Van Car Rentals in Liberty
- Car rental Pickens
- Pickup Car Rentals in Pickens
- Van Car Rentals in Pickens
- Car rental Central






