Book Hotels in Six Mile, SC
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Top Six Mile hotels

Wooded Cottage - 3 Mi to Clemson University
Clemson SC
Free WiFi in public areas is available at this cottage.

The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $185 total per night from Dec 7 to Dec 8
$185 total
Dec 7 - Dec 8
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
BEST hotel in all of Clemson!
Reviewed on Nov 15, 2025

Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more
Six Mile SC
This vacation home featured laundry facilities and barbecue grills.
The hosts were amazing! So responsive and helpful. Great house.
Reviewed on Nov 11, 2025

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $93 total per night from Nov 27 to Nov 28
$93 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Clean; good breakfast; kind staff
Reviewed on Nov 23, 2025

Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $104 total per night from Dec 21 to Dec 22
$104 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Ease of checking in
Reviewed on Nov 23, 2025

Microtel Inn & Suites by Wyndham Anderson/Clemson
102 Electric City Blvd Anderson SC
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $89 total per night from Nov 26 to Nov 27
$89 total
Nov 26 - Nov 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
Room was clean, staff was nice!
Reviewed on Nov 14, 2025

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $89 total per night from Dec 7 to Dec 8
$89 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Clean room w fridge and microwave Comfy bed
Reviewed on Nov 15, 2025

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Nov 26 to Nov 27
$70 total
Nov 26 - Nov 27
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Clean rooms, safe and clean property, top notch customer service the owner and front desk are all wonderful from start to finish. You wont regret a second here.
Reviewed on Nov 17, 2025

Quality Inn Clemson near University
3430 Clemson Blvd Anderson SC
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $56 total per night from Dec 9 to Dec 10
$56 total
Dec 9 - Dec 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...
Shopping is good nears around
Reviewed on Sep 27, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Six Mile hotel reviews by fellow wanderers

Comfort Inn & Suites Clemson - University Area
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Ease of checking in"
A verified traveler stayed at Comfort Inn & Suites Clemson - University Area
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