Book Hotels in Six Mile, SC
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Top Six Mile hotels

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
299 Outpost Rd Seneca SC
$133 nightly
The price is $146 total per night from May 20 to May 21
$146 total
May 20 - May 21
Total with taxes and fees
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
Great spot for couples wanting to connect or a solo trip.
Reviewed on Apr 2, 2026

The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
$199 nightly
The price is $221 total per night from Apr 22 to Apr 23
$221 total
Apr 22 - Apr 23
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
Great location great restaurant
Reviewed on Apr 20, 2026

Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more
Six Mile SC
This vacation home features a garden, laundry facilities, and barbecue grills.
Well stocked, loved the dock and screened in porch!
Reviewed on Apr 13, 2026

Clemson University's James F. Martin Inn
240 Madren Center Drive Clemson SC
$149 nightly
The price is $165 total per night from Apr 22 to Apr 23
$165 total
Apr 22 - Apr 23
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center ...
Have a big difference from its past. The view is bad, seems no bar for evening meeting.
Reviewed on Apr 21, 2026

Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
$123 nightly
The price is $135 total per night from Apr 22 to Apr 23
$135 total
Apr 22 - Apr 23
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
great place
Reviewed on Apr 20, 2026

Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd Clemson SC
Fully refundable
$101 nightly
The price is $112 total per night from May 12 to May 13
$112 total
May 12 - May 13
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Large room & bathroom
Reviewed on Apr 20, 2026

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
$105 nightly
The price is $117 total per night from Apr 24 to Apr 25
$117 total
Apr 24 - Apr 25
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Great location to area amenities and nice attached restaurant and breakfast buffet.
Reviewed on Apr 21, 2026

Inn @ Clemson
1303 Tiger Blvd Clemson SC
$90 nightly
The price is $100 total per night from Apr 27 to Apr 28
$100 total
Apr 27 - Apr 28
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Bed was clean but hotel in general is not great. Would not stay here again
Reviewed on Apr 20, 2026

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $68 total per night from Apr 26 to Apr 27
$68 total
Apr 26 - Apr 27
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
The whole place reaked of marijuna the whole staff must of been smoking it we put our stuff in the room and left to meet some of the family we were down for my husbands brothers funeral like I said we left to meet some of the family and got back to the room around 9 or 9:30 and walked in to the room ...
Reviewed on Apr 21, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Six Mile hotel reviews by fellow wanderers

Days Inn by Wyndham Anderson
1 out of 5
Posted 1 hour ago
Travelocity Verified Review
"The whole place reaked of marijuna the whole staff must of been smoking it we put our stuff in the room and left to meet some of the family we were down for my husbands brothers funeral like I said we left to meet some of the family and got back to the room around 9 or 9:30 and walked in to the room and smelled like someone had been in our room smoking marijuana it was so strong it would knock you down so they tried to move us to another room and my husband went to check the bed and he pulled the blanket from under the corner of Mattress and found a bed bug on his thumb so would I recommend this place No I Wouldn’t "
A verified traveler stayed at Days Inn by Wyndham Anderson
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