Book Hotels in Six Mile, SC
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Top Six Mile hotels

Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more
Six Mile SC
This vacation home features a garden, laundry facilities, and barbecue grills.
Wonderful last minute decision to go to the lake, great communication the night before, everything worked out , home is at the end of a cove with a covered boat dock( accommodated our fishing boat perfectly) access to kayak and paddle boats, life vests made for a great experience. Fire pit area was ...
Reviewed on May 12, 2026

The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
$189 nightly
The price is $210 total per night from May 17 to May 18
$210 total
May 17 - May 18
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
It’s the best small boutique hotel and the cleanest in all of Clemson. This is always my first choice if available.
Reviewed on May 5, 2026

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
299 Outpost Rd Seneca SC
$133 nightly
The price is $146 total per night from Jun 15 to Jun 16
$146 total
Jun 15 - Jun 16
Total with taxes and fees
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
Awesome place
Reviewed on May 9, 2026

Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from May 17 to May 18
$135 total
May 17 - May 18
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
Only problem was that some of their floor laminate was separating.
Reviewed on May 16, 2026

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $122 total per night from May 18 to May 19
$122 total
May 18 - May 19
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Room was clean bed slept very good. Everyone that worked. There were very accommodating great location. This is my fourth time staying at this hotel.
Reviewed on May 14, 2026

OUTER BANKS
Six Mile SC
A gym is featured at this vacation home, along with laundry facilities and barbecue grills.
Beautiful location and it was very nice being able to use the coffee in the pantry!
Reviewed on Apr 12, 2026

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $65 total per night from Jun 11 to Jun 12
$65 total
Jun 11 - Jun 12
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Sam working at front desk helped tremendously. I was working and traveling really late / early in the morning. Sam was able to accommodate me and got me checked in with ease. Great service! Thank you Sam.
Reviewed on May 15, 2026

Inn @ Clemson
1303 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $90 total per night from May 17 to May 18
$90 total
May 17 - May 18
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Great place to stay while in Clemson. Close to everything
Reviewed on May 14, 2026

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Fully refundable
$92 nightly
The price is $101 total per night from Jun 14 to Jun 15
$101 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Our room was very clean, spacious, and nicely decorated. The facility and grounds were obviously very well cared for, and the amenities were quite nice.
Reviewed on May 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Six Mile hotel reviews by fellow wanderers

Lakeside Lodge Clemson
5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Only problem was that some of their floor laminate was separating. "
A verified traveler stayed at Lakeside Lodge Clemson
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