Book Hotels in Six Mile, SC
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Top Six Mile hotels

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
299 Outpost Rd Seneca SC
$139 nightly
The price is $153 total per night from Mar 25 to Mar 26
$153 total
Mar 25 - Mar 26
Total with taxes and fees
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
I bought things like plates, towels,
Reviewed on Mar 8, 2026

The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
$224 nightly
The price is $249 total per night from Apr 20 to Apr 21
$249 total
Apr 20 - Apr 21
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
Loved our time here! Staff was super sweet and helpful. Room was very nice and the bed very cozy. Room felt a little small but the bathroom was larger than expected, and again all nice and clean. No complaints! Great place to stay when in the area! Love the mission to help those differently abled, ...
Reviewed on Mar 20, 2026

Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more
Six Mile SC
This vacation home features a garden, laundry facilities, and barbecue grills.
Everything was wonderful! The host was very responsive with any questions we had. We would certainly stay here again!
Reviewed on Feb 22, 2026

Clemson University's James F. Martin Inn
240 Madren Center Drive Clemson SC
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $165 total per night from Mar 25 to Mar 26
$165 total
Mar 25 - Mar 26
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center ...
Linens were scratchy and mold growing in showers
Reviewed on Mar 22, 2026

Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Mar 29 to Mar 30
$135 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
The unit was terrific. Quiet and clean. only issue is daily train whistle nearby. Nice area with grrat restaurant in hotel.
Reviewed on Mar 21, 2026

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $115 total per night from Apr 3 to Apr 4
$115 total
Apr 3 - Apr 4
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
I enjoyed my stay at the BW Plus. It's super convenient (I walked home from downtown one night - not a short walk but very manageable). The property was clean, the staff was VERY friendly, the room was more than adequate (I had 2 queens and it had a desk/chair and side chair with 'breakfast tray.' ...
Reviewed on Mar 20, 2026

Inn @ Clemson
1303 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $97 total per night from Mar 25 to Mar 26
$97 total
Mar 25 - Mar 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
All of the staff we encountered were extremely nice and helpful. The beds were very comfortable thoroughly enjoyed our stay.
Reviewed on Mar 21, 2026

Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd Clemson SC
Fully refundable
$105 nightly
The price is $117 total per night from Apr 13 to Apr 14
$117 total
Apr 13 - Apr 14
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Nice large room woth comfortable bed. Toilet paper was thin. Nice large television. Breakfast was good. Liked that that they changed it slightly each day.
Reviewed on Mar 22, 2026

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $68 total per night from Apr 12 to Apr 13
$68 total
Apr 12 - Apr 13
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Asked if we had pets. Someone was always at the counter when needed. Upgrade deluxe if available
Reviewed on Mar 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Six Mile hotel reviews by fellow wanderers

Days Inn by Wyndham Anderson
5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Asked if we had pets. Someone was always at the counter when needed. Upgrade deluxe if available "
A verified traveler stayed at Days Inn by Wyndham Anderson
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