Book Hotels in Six Mile, SC
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Top Six Mile hotels

The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
$195 nightly
The price is $216 total per night from May 18 to May 19
$216 total
May 18 - May 19
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
Great stay. Easy walk to Clemson University.
Reviewed on Apr 12, 2026

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
299 Outpost Rd Seneca SC
$133 nightly
The price is $146 total per night from May 17 to May 18
$146 total
May 17 - May 18
Total with taxes and fees
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
Great spot for couples wanting to connect or a solo trip.
Reviewed on Apr 2, 2026

The Inn at Patrick Square
115 Market Street Clemson SC
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $176 total per night from Apr 20 to Apr 21
$176 total
Apr 20 - Apr 21
Total with taxes and fees
A 24-hour gym is featured at this hotel, along with free self parking. WiFi in public areas is free. Staff at the 24-hour front desk can provide around-the-clock ...
Quaint boutique hotel. Clean and staff was excellent. Would stay again.
Reviewed on Apr 16, 2026

Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more
Six Mile SC
This vacation home features a garden, laundry facilities, and barbecue grills.
Well stocked, loved the dock and screened in porch!
Reviewed on Apr 13, 2026

Clemson University's James F. Martin Inn
240 Madren Center Drive Clemson SC
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $165 total per night from Apr 19 to Apr 20
$165 total
Apr 19 - Apr 20
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center ...
Suite was amazing. Large enough for a family of 6.
Reviewed on Apr 17, 2026

Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Apr 20 to Apr 21
$135 total
Apr 20 - Apr 21
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
This place is tops! The area is great, rooms were wonderful, and amenities were amazing. Definitely plan on staying again asap!
Reviewed on Apr 9, 2026

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $112 total per night from May 11 to May 12
$112 total
May 11 - May 12
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Great services great people
Reviewed on Apr 13, 2026

Inn @ Clemson
1303 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $101 total per night from Apr 20 to Apr 21
$101 total
Apr 20 - Apr 21
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Clean room and convenient to campus!
Reviewed on Apr 15, 2026

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $65 total per night from Apr 19 to Apr 20
$65 total
Apr 19 - Apr 20
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Very, very clean and friendly staff.
Reviewed on Apr 16, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Six Mile hotel reviews by fellow wanderers

Clemson University's James F. Martin Inn
5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Suite was amazing. Large enough for a family of 6. "
A verified traveler stayed at Clemson University's James F. Martin Inn
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