Book Hotels in Six Mile, SC

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Top Six Mile hotels

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
$219 nightly
The price is $243 total per night from Mar 15 to Mar 16
$243 total
Mar 15 - Mar 16
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
All was excellent

Reviewed on Feb 23, 2026

Opens in a new windowThe Shepherd Hotel Downtown Clemson
Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more

Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more

Six Mile SC
This vacation home featured laundry facilities and barbecue grills.
Everything was wonderful! The host was very responsive with any questions we had. We would certainly stay here again!

Reviewed on Feb 22, 2026

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Opens in a new windowLake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

3 out of 5
240 Madren Center Drive Clemson SC
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $165 total per night from Mar 1 to Mar 2
$165 total
Mar 1 - Mar 2
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center ...
Excellent facilities. The views are incredible. This was my third stay - I'll definitely return. GO TIGERS!

Reviewed on Feb 24, 2026

Opens in a new windowClemson University's James F. Martin Inn
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Mar 1 to Mar 2
$135 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
Clean room, great service!

Reviewed on Feb 23, 2026

Opens in a new windowLakeside Lodge Clemson
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $101 total per night from Mar 1 to Mar 2
$101 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
N/a

Reviewed on Feb 25, 2026

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $108 total per night from Mar 4 to Mar 5
$108 total
Mar 4 - Mar 5
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Clean room. It was good sized with the King bed and sofa. Nice bathroom. Large TV was a plus. Breakfast was surprisingly good with eggs, sausage, potatoes, biscuits with sausage gravy, waffles, cereal, oatmeal, bagels, toast, orange juice and apple juices. Occasional sound from the train wasn't too ...

Reviewed on Feb 24, 2026

Opens in a new windowComfort Inn & Suites Clemson - University Area
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $92 total per night from Mar 5 to Mar 6
$92 total
Mar 5 - Mar 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
All great

Reviewed on Feb 21, 2026

Opens in a new windowQuality Inn Seneca Clemson Area US-123
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Mar 1 to Mar 2
$70 total
Mar 1 - Mar 2
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Ready to stay again love using this for my staycations

Reviewed on Feb 25, 2026

Opens in a new windowDays Inn by Wyndham Anderson
Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson SC
Free WiFi in public areas is available at this cottage.
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Opens in a new windowWooded Cottage - 3 Mi to Clemson University
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Where can I find cheap hotels in Six Mile?
At Travelocity you'll find really nice hotels in Six Mile at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Six Mile rather than in Six Mile. We may find you even better rates, too.
How do I find the best Six Mile hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Six Mile then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Six Mile?
The cheapest hotel in Six Mile is $70. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Six Mile?
There are 1,525 hotels in Six Mile on Travelocity.
What are the best hotels in Six Mile?
Six Mile has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Six Mile for you!
When is the best time to visit Six Mile?
If you want the joy of a fun-filled trip in peak season, visit Six Mile during March, July and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as October, November and December.
When is the cheapest time to stay in Six Mile?
Based on historic data is usually the cheapest month to visit Six Mile. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Six Mile?
There are multiple hotels in Six Mile that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Six Mile. We have plenty of kid-friendly hotels in Six Mile to choose from on Travelocity!
Why book a hotel in Six Mile through Travelocity?
Because we have the top hotels in Six Mile! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Six Mile on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Six Mile hotel reviews by fellow wanderers

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Great having a washer and dry available and the breakfast staff was amazing and very nice."
A verified traveler from temple hills stayed at Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area

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