Book Hotels in Saint Charles, IA

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Saint Charles hotels

Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $178 total per night from Sep 27 to Sep 28
$178 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
"My only complaint was cheap toilet paper!"

Reviewed on Sep 21, 2026

Opens in a new windowDes Lux Hotel
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $141 total per night from Oct 11 to Oct 12
$141 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
"Loved the hotel and the restaurants. Will stay here again"

Reviewed on Sep 20, 2026

Opens in a new windowHotel Fort Des Moines, Curio Collection by Hilton
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
$110 nightly
The price is $123 total per night from Oct 18 to Oct 19
$123 total
Oct 18 - Oct 19
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Free perks include continental breakfast, free self parking, and a roundtrip airport shuttle. You'll appreciate ...
"Overall the room was great and the bed and pillows were super comfortable, but the room smelt like something burned in there. The free breakfast was just ok, and one the morning from desk clerk was not overly pleasant and the cleaning crew just didn't speak to us."

Reviewed on Sep 20, 2026

Opens in a new windowHampton Inn Des Moines-Airport
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Sep 30 to Oct 1
$79 total
Sep 30 - Oct 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"The location was close to the airport which was a plus. Check in took a while and there was no one in front of me. I chose a room with a king sized bed. The room was next to the elevator- very noisy. The hotel was less than half full so not sure why our king room was one next to the elevator. I'm ..."

Reviewed on Sep 20, 2026

Opens in a new windowDays Inn & Suites by Wyndham Des Moines Airport
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $118 total per night from Sep 22 to Sep 23
$118 total
Sep 22 - Sep 23
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A business ...
Opens in a new windowWildwood Lodge
Country Inn & Suites by Radisson, Des Moines West, IA

Country Inn & Suites by Radisson, Des Moines West, IA

3 out of 5
1350 Nw 118th St Clive IA
Fully refundable
$84 nightly
The price is $94 total per night from Sep 27 to Sep 28
$94 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Opens in a new windowCountry Inn & Suites by Radisson, Des Moines West, IA
Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West

3 out of 5
7225 Vista Dr West Des Moines IA
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $108 total per night from Oct 18 to Oct 19
$108 total
Oct 18 - Oct 19
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Opens in a new windowFairfield Inn and Suites by Marriott Des Moines West
Embassy Suites Hotel Des Moines Downtown

Embassy Suites Hotel Des Moines Downtown

3.5 out of 5
101 E Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $146 total per night from Oct 11 to Oct 12
$146 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free full breakfast each morning. Valet parking, a 24-hour business ...
Opens in a new windowEmbassy Suites Hotel Des Moines Downtown
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N West Des Moines IA
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $67 total per night from Sep 22 to Sep 23
$67 total
Sep 22 - Sep 23
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace, a snack bar/deli, and laundry facilities are also on ...
Opens in a new windowMotel 6 West Des Moines, IA
Don't see what you're looking for?
See all available properties in Saint Charles
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Where can I find cheap hotels in Saint Charles?
At Travelocity you'll find really nice hotels in Saint Charles at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Saint Charles rather than in Saint Charles. We may find you even better rates, too.
How do I find the best Saint Charles hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Saint Charles then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Saint Charles?
The cheapest hotel in Saint Charles is $67. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Saint Charles?
There are 603 hotels in Saint Charles on Travelocity.
What are the best hotels in Saint Charles?
Saint Charles has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Saint Charles for you!
When is the best time to visit Saint Charles?
If you want the joy of a fun-filled trip in peak season, visit Saint Charles during February, April and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Saint Charles?
Based on historic data is usually the cheapest month to visit Saint Charles. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Saint Charles?
There are multiple hotels in Saint Charles that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Saint Charles. We have plenty of kid-friendly hotels in Saint Charles to choose from on Travelocity!
Why book a hotel in Saint Charles through Travelocity?
Because we have the top hotels in Saint Charles! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Saint Charles on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Saint Charles hotel reviews by fellow wanderers

Des Lux Hotel

Des Lux Hotel

4 out of 5
Posted 9 hours ago
Travelocity Verified Review
"My only complaint was cheap toilet paper!"
A verified traveler stayed at Des Lux Hotel
Des Lux Hotel

Explore More Ways to Travel with Travelocity