Book Hotels in Saint Charles, IA

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Saint Charles hotels

Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$189 nightly
The price is $212 total per night from Aug 6 to Aug 7
$212 total
Aug 6 - Aug 7
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
"Absolutely amazing stay at the Des Lux! Highly recommended!"

Reviewed on Jul 29, 2026

Opens in a new windowDes Lux Hotel
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $161 total per night from Aug 23 to Aug 24
$161 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
"Very clean hotel, quiet, friendly staff, and the building is gorgeous!"

Reviewed on Jul 30, 2026

Opens in a new windowHotel Fort Des Moines, Curio Collection by Hilton
Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines

3 out of 5
5505 Mills Civic Pkwy West Des Moines IA
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Aug 9 to Aug 10
$112 total
Aug 9 - Aug 10
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"The breakfast was fabulous and the happy hour/kickback food was also terrific! The location is superb, we will definitely be back! Hopefully the next time we visit they will have both elevators running. It got a little tight with just one elevator at the busy time in the morning as people were checking ..."

Reviewed on Jul 30, 2026

Opens in a new windowDrury Inn & Suites West Des Moines
Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West

3 out of 5
7225 Vista Dr West Des Moines IA
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Aug 23 to Aug 24
$114 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Clean room excellent breakfast"

Reviewed on Jul 30, 2026

Opens in a new windowFairfield Inn and Suites by Marriott Des Moines West
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $88 total per night from Aug 10 to Aug 11
$88 total
Aug 10 - Aug 11
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Room was clean, staff was very helpful"

Reviewed on Jul 31, 2026

Opens in a new windowDays Inn & Suites by Wyndham Des Moines Airport
Sonesta Simply Suites Des Moines

Sonesta Simply Suites Des Moines

2.5 out of 5
7625 Office Plaza Dr N West Des Moines IA
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $86 total per night from Aug 23 to Aug 24
$86 total
Aug 23 - Aug 24
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A terrace, a snack bar/deli, and a grocery/convenience ...
"Arrived very late after booking online. I was told they couldn't honor our reservation because they had rooms with mechanical issues, so nothing was available. I can't rate much else because we had to find another hotel at 11 pm."

Reviewed on Jul 30, 2026

Opens in a new windowSonesta Simply Suites Des Moines
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $118 total per night from Aug 30 to Aug 31
$118 total
Aug 30 - Aug 31
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Opens in a new windowHome2 Suites by Hilton Des Moines at Drake University
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $159 total per night from Aug 20 to Aug 21
$159 total
Aug 20 - Aug 21
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A business ...
Opens in a new windowWildwood Lodge
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N West Des Moines IA
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $86 total per night from Aug 11 to Aug 12
$86 total
Aug 11 - Aug 12
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace, a snack bar/deli, and laundry facilities are also on ...
Opens in a new windowMotel 6 West Des Moines, IA
Don't see what you're looking for?
See all available properties in Saint Charles
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Where can I find cheap hotels in Saint Charles?
At Travelocity you'll find really nice hotels in Saint Charles at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Saint Charles rather than in Saint Charles. We may find you even better rates, too.
How do I find the best Saint Charles hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Saint Charles then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Saint Charles?
The cheapest hotel in Saint Charles is $86. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Saint Charles?
There are 644 hotels in Saint Charles on Travelocity.
What are the best hotels in Saint Charles?
Saint Charles has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Saint Charles for you!
When is the best time to visit Saint Charles?
If you want the joy of a fun-filled trip in peak season, visit Saint Charles during February, April and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Saint Charles?
Based on historic data is usually the cheapest month to visit Saint Charles. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Saint Charles?
There are multiple hotels in Saint Charles that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Saint Charles. We have plenty of kid-friendly hotels in Saint Charles to choose from on Travelocity!
Why book a hotel in Saint Charles through Travelocity?
Because we have the top hotels in Saint Charles! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Saint Charles on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Saint Charles hotel reviews by fellow wanderers

Clarion Inn Des Moines Airport

Clarion Inn Des Moines Airport

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"We stayed one night and utilized the airport shuttle in the morning. All the staff were nice and helpful with our questions. The shuttle runs 24/7, so we were able to get a ride to the airport when needed. When we arrived back we made a quick call to the hotel and the shuttle was there to get us within 5 minutes. Quick, easy, and reliable service all around!! I also left my AirPods behind in the room, and they kept them safe in the lost and found! Even offered to mail them back to my house, but I wasn’t far away when I noticed they were gone. We will be staying here again in the future!!"
A verified traveler stayed at Clarion Inn Des Moines Airport
Clarion Inn Des Moines Airport

Explore More Ways to Travel with Travelocity