Book Hotels in Saint Charles, IA

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Saint Charles hotels

Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $189 total per night from Apr 26 to Apr 27
$189 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
Nice breakfast. First room had a sink that was a bit dirty, moved us to a new room immediately Really enjoyed our stay.

Reviewed on Apr 19, 2026

Opens in a new windowDes Lux Hotel
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $161 total per night from Apr 26 to Apr 27
$161 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Room was very clean and well maintained. Very comfortable pillows. Our room was right by the elevators but must have excellent soundproofing because we didn’t hear anything from the hall or other rooms.

Reviewed on Apr 19, 2026

Opens in a new windowHotel Fort Des Moines, Curio Collection by Hilton
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $116 total per night from Apr 26 to Apr 27
$116 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like full breakfast and free self parking. A business center, free WiFi in public ...
Desk clerk knew that I was a gold member at Expedia, welcomed me to Wildwood, & remembered my name the next morning -- gracious & helpful & proud of where she worked. The Lodge has a great ambience & us family-friendly. Breakfast was very good. When I asked for a possible free upgrade, we got a ...

Reviewed on Apr 19, 2026

Opens in a new windowWildwood Lodge
Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines

3 out of 5
5505 Mills Civic Pkwy West Des Moines IA
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Apr 26 to Apr 27
$112 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Beautiful hotel, courteous & helpful staff. Convenient location off the I35 roadway.

Reviewed on Apr 18, 2026

Opens in a new windowDrury Inn & Suites West Des Moines
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Apr 26 to Apr 27
$109 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Bathroom door track in rm 210 is faulty. Bathroom door does not close all the way

Reviewed on Apr 20, 2026

Opens in a new windowHome2 Suites by Hilton Des Moines at Drake University
Hyatt Place West Des Moines Jordan Creek

Hyatt Place West Des Moines Jordan Creek

3 out of 5
295 South 64th st West Des Moines IA
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $114 total per night from Apr 27 to Apr 28
$114 total
Apr 27 - Apr 28
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Need ice machine on every floor

Reviewed on Apr 17, 2026

Opens in a new windowHyatt Place West Des Moines Jordan Creek
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Apr 26 to Apr 27
$76 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Room was clean, but had a very musty smell to it as did the entire hotel. We came in one night after a very long day and there was an entire beverage spilled on the elevator floor. No efforts were made to clean it except a “wet floor” sign. The next morning we get packed up for another long day only ...

Reviewed on Apr 18, 2026

Opens in a new windowDays Inn & Suites by Wyndham Des Moines Airport
Embassy Suites Hotel Des Moines Downtown

Embassy Suites Hotel Des Moines Downtown

3.5 out of 5
101 E Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $137 total per night from Apr 26 to Apr 27
$137 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free full breakfast each morning. Valet parking, a 24-hour business ...
The heater is noisy entire time , the TV is not turning ON - we have to report that problems and the good thing is maintenance comes so quickly

Reviewed on Apr 19, 2026

Opens in a new windowEmbassy Suites Hotel Des Moines Downtown
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N West Des Moines IA
Fully refundableReserve now, pay when you stay
$51 nightly
The price is $57 total per night from Apr 27 to Apr 28
$57 total
Apr 27 - Apr 28
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace, a snack bar/deli, and laundry facilities are also on ...
As always this place is better than expected!

Reviewed on Apr 19, 2026

Opens in a new windowMotel 6 West Des Moines, IA
Don't see what you're looking for?
See all available properties in Saint Charles
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Where can I find cheap hotels in Saint Charles?
At Travelocity you'll find really nice hotels in Saint Charles at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Saint Charles rather than in Saint Charles. We may find you even better rates, too.
How do I find the best Saint Charles hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Saint Charles then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Saint Charles?
The cheapest hotel in Saint Charles is $57. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Saint Charles?
There are 613 hotels in Saint Charles on Travelocity.
What are the best hotels in Saint Charles?
Saint Charles has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Saint Charles for you!
When is the best time to visit Saint Charles?
If you want the joy of a fun-filled trip in peak season, visit Saint Charles during February, April and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Saint Charles?
Based on historic data is usually the cheapest month to visit Saint Charles. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Saint Charles?
There are multiple hotels in Saint Charles that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Saint Charles. We have plenty of kid-friendly hotels in Saint Charles to choose from on Travelocity!
Why book a hotel in Saint Charles through Travelocity?
Because we have the top hotels in Saint Charles! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Saint Charles on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Saint Charles hotel reviews by fellow wanderers

Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

4 out of 5
Posted 3 hours ago
Travelocity Verified Review
"Bathroom door track in rm 210 is faulty. Bathroom door does not close all the way"
A verified traveler stayed at Home2 Suites by Hilton Des Moines at Drake University
Home2 Suites by Hilton Des Moines at Drake University

Explore More Ways to Travel with Travelocity