Book Hotels in Saint Charles, IA

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Top Saint Charles hotels

Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $189 total per night from Apr 19 to Apr 20
$189 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
Will be back

Reviewed on Apr 16, 2026

Opens in a new windowDes Lux Hotel
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $161 total per night from Apr 26 to Apr 27
$161 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
My favorite place to stay in Des Moines! Rooms are always soo clean, the service is top notch, the restaurant is delicious and so close to many restaurants and cocktail bars. It’s truly the best!

Reviewed on Apr 15, 2026

Opens in a new windowHotel Fort Des Moines, Curio Collection by Hilton
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $116 total per night from May 10 to May 11
$116 total
May 10 - May 11
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like full breakfast and free self parking. A business center, free WiFi in public ...
What a wonderful surprise. When you're traveling. You never really know what to expect. I can tell you this place far surpasses anything we ever imagined. We will definitely stay there again.

Reviewed on Apr 15, 2026

Opens in a new windowWildwood Lodge
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Apr 26 to Apr 27
$109 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
The room was exceptional! Very clean, comfortable, and well appointed! Highly recommend a stay!

Reviewed on Apr 16, 2026

Opens in a new windowHome2 Suites by Hilton Des Moines at Drake University
Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines

3 out of 5
5505 Mills Civic Pkwy West Des Moines IA
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Apr 20 to Apr 21
$112 total
Apr 20 - Apr 21
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
The room was very clean, and the staff was friendly.

Reviewed on Apr 16, 2026

Opens in a new windowDrury Inn & Suites West Des Moines
Hyatt Place West Des Moines Jordan Creek

Hyatt Place West Des Moines Jordan Creek

3 out of 5
295 South 64th st West Des Moines IA
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $108 total per night from Apr 27 to Apr 28
$108 total
Apr 27 - Apr 28
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Clean, nice, friendly staff. No complaints

Reviewed on Apr 7, 2026

Opens in a new windowHyatt Place West Des Moines Jordan Creek
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Apr 26 to Apr 27
$76 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
One of my favorites hotel is this one

Reviewed on Apr 16, 2026

Opens in a new windowDays Inn & Suites by Wyndham Des Moines Airport
Sonesta Simply Suites Des Moines

Sonesta Simply Suites Des Moines

2.5 out of 5
7625 Office Plaza Dr N West Des Moines IA
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $85 total per night from Apr 19 to Apr 20
$85 total
Apr 19 - Apr 20
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A terrace, a snack bar/deli, and a grocery/convenience ...
The room is very well set up like a studio apartment. I couldn't have asked for a better place to spend the night.

Reviewed on Apr 13, 2026

Opens in a new windowSonesta Simply Suites Des Moines
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

3 out of 5
1050 6th Ave Des Moines IA
Fully refundable
$142 nightly
The price is $159 total per night from Apr 19 to Apr 20
$159 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the gym and perks like free WiFi and a free airport shuttle. A 24-hour business center, ...
Room wasn’t ready until nearly 2 hours after check in time. No real good place to hang out in lobby. We asked about the conference room that wasn’t being used. Front desk told us no but then bartender opened it up for us.

Reviewed on Apr 16, 2026

Opens in a new windowHoliday Inn Downtown - Mercy Area by IHG
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See all available properties in Saint Charles
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Where can I find cheap hotels in Saint Charles?
At Travelocity you'll find really nice hotels in Saint Charles at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Saint Charles rather than in Saint Charles. We may find you even better rates, too.
How do I find the best Saint Charles hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Saint Charles then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Saint Charles?
The cheapest hotel in Saint Charles is $76. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Saint Charles?
There are 614 hotels in Saint Charles on Travelocity.
What are the best hotels in Saint Charles?
Saint Charles has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Saint Charles for you!
When is the best time to visit Saint Charles?
If you want the joy of a fun-filled trip in peak season, visit Saint Charles during February, April and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Saint Charles?
Based on historic data is usually the cheapest month to visit Saint Charles. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Saint Charles?
There are multiple hotels in Saint Charles that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Saint Charles. We have plenty of kid-friendly hotels in Saint Charles to choose from on Travelocity!
Why book a hotel in Saint Charles through Travelocity?
Because we have the top hotels in Saint Charles! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Saint Charles on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Saint Charles hotel reviews by fellow wanderers

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Very nice clean room. Especially for the price! "
A verified traveler stayed at Motel 6 West Des Moines, IA
Motel 6 West Des Moines, IA

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