Book Hotels in Saint Charles, IA
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Top Saint Charles hotels

Des Lux Hotel
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $200 total per night from Jun 18 to Jun 19
$200 total
Jun 18 - Jun 19
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
"Awesome staff, unique environment, great location"
Reviewed on Jun 14, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $146 total per night from Jul 3 to Jul 4
$146 total
Jul 3 - Jul 4
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
"Great hotel. Attention to detail, beautiful hotel. Staff in cafe were all miserable apart from one but good food"
Reviewed on Jun 15, 2026

Drury Inn & Suites West Des Moines
5505 Mills Civic Pkwy West Des Moines IA
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Jun 21 to Jun 22
$112 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Clean room, great amenities and staff. Enjoyed our stay."
Reviewed on Jun 15, 2026

Home2 Suites by Hilton Des Moines at Drake University
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $118 total per night from Jun 21 to Jun 22
$118 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Great central location for my leadership classes at Drake plus central to get to several local spots for a brewery or good food."
Reviewed on Jun 13, 2026

Fairfield Inn and Suites by Marriott Des Moines West
7225 Vista Dr West Des Moines IA
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Jun 21 to Jun 22
$114 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Very helpful and kind staff at check in. The breakfast was good with variety. Some of the lobby chairs were showing wear but everything was clean and in working order. Room was good size, clean and comfortable."
Reviewed on Jun 14, 2026

Fairfield Inn & Suites by Marriott Des Moines Downtown
207 Crocker Street Des Moines IA
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $103 total per night from Jul 5 to Jul 6
$103 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
"Passing thru Des Moines and just needed a place to sleep. Looking online and saw they had rooms for $106. Got 2 rooms and WOW! The rooms were huge, exceptionally clean, great beds and pillows plus the view was awesome! Will definitely stay again."
Reviewed on Jun 15, 2026

Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Jun 21 to Jun 22
$81 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Clean room. Friendly staff and easy parking."
Reviewed on Jun 14, 2026

Holiday Inn Downtown - Mercy Area by IHG
1050 6th Ave Des Moines IA
Fully refundable
$128 nightly
The price is $143 total per night from Jun 28 to Jun 29
$143 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the gym and perks like free WiFi and a free airport shuttle. A 24-hour business center, ...
"So many problems. The parking lot being closed for over a year is absolutely unacceptable, especially for the handicapped. Guest are to park in the hospital parking lot and walk at least a quarter mile with all of their luggage just to check in. With the number of transients, horrible lighting, and ..."
Reviewed on Jun 14, 2026

Clarion Inn Des Moines Airport
1810 Army Post Road Des Moines IA
Fully refundable
$68 nightly
The price is $76 total per night from Jun 23 to Jun 24
$76 total
Jun 23 - Jun 24
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"I liked everything about this place"
Reviewed on Jun 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Saint Charles hotel reviews by fellow wanderers

Wildwood Lodge
5 out of 5
Posted 12 hours ago
Travelocity Verified Review
"Clean room, great hot breakfast and a cozy environment"
A verified traveler stayed at Wildwood Lodge
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