Book Hotels in Saint Charles, IA

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Top Saint Charles hotels

Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St, Des Moines, IA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $189 total per night from Sep 29 to Sep 30
$189 total
Sep 29 - Sep 30
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
"Very nice property. I would recommend a stay here for a concert or any downtown Des Moines activities."

Reviewed on Sep 20, 2025

Opens in a new windowDes Lux Hotel
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St, Des Moines, IA
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $161 total per night from Oct 19 to Oct 20
$161 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. Valet parking, a business center, and a coffee shop are also ...
Great location downtown Des Moines
"Stayed one night for a concert at the amphitheater. Perfect location with plenty of dinner options close by. Hotel was very nice, the room was super clean."

Reviewed on Sep 19, 2025

Opens in a new windowHotel Fort Des Moines, Curio Collection by Hilton
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave., Des Moines, IA
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $129 total per night from Oct 26 to Oct 27
$129 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Always our go to in Des moines"

Reviewed on Sep 25, 2025

Opens in a new windowHome2 Suites by Hilton Des Moines at Drake University
Hilton Des Moines Downtown

Hilton Des Moines Downtown

3.5 out of 5
435 Park Street, Des Moines, IA
$157 nightly
The price is $176 total per night from Oct 4 to Oct 5
$176 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and free ...
"Location was great. Rooms were clean. Beds seemdled small although was supposed to be two queens it seemd more like fulls."

Reviewed on Sep 20, 2025

Opens in a new windowHilton Des Moines Downtown
Comfort Inn & Suites Event Center

Comfort Inn & Suites Event Center

2.5 out of 5
929 3rd St, Des Moines, IA
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $121 total per night from Oct 27 to Oct 28
$121 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies like buffet ...
"We had poor directions from google. We tried to telephone the hotel and speak to someone at the property, but were never able to reach them by phone. It kept going to reservation."

Reviewed on Sep 24, 2025

Opens in a new windowComfort Inn & Suites Event Center
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave, Des Moines, IA
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $86 total per night from Oct 12 to Oct 13
$86 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Friendly and convenient to airport. Shuttle service was great!"

Reviewed on Sep 23, 2025

Opens in a new windowDays Inn & Suites by Wyndham Des Moines Airport
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

3 out of 5
1050 6th Ave, Des Moines, IA
Fully refundable
$121 nightly
The price is $135 total per night from Oct 27 to Oct 28
$135 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the gym and perks like free WiFi and a free airport shuttle. A 24-hour business center, ...
"Nice hotel and clean room"

Reviewed on Sep 21, 2025

Opens in a new windowHoliday Inn Downtown - Mercy Area by IHG
Hyatt Place Des Moines/Downtown

Hyatt Place Des Moines/Downtown

3 out of 5
418 6th Avenue, Des Moines, IA
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Oct 6 to Oct 7
$123 total
Oct 6 - Oct 7
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Big room"

Reviewed on Sep 18, 2025

Opens in a new windowHyatt Place Des Moines/Downtown
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N, West Des Moines, IA
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $56 total per night from Oct 14 to Oct 15
$56 total
Oct 14 - Oct 15
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace, a snack bar/deli, and laundry facilities are also on ...
"This is the Ritz of Motel 6s. The room was clean, in decent condition, and everything worked."

Reviewed on Sep 22, 2025

Opens in a new windowMotel 6 West Des Moines, IA
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Where can I find cheap hotels in Saint Charles?
At Travelocity you'll find really nice hotels in Saint Charles at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Saint Charles rather than in Saint Charles. We may find you even better rates, too.
How do I find the best Saint Charles hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Saint Charles then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Saint Charles?
The cheapest hotel in Saint Charles is $56. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Saint Charles?
There are 581 hotels in Saint Charles on Travelocity.
What are the best hotels in Saint Charles?
Saint Charles has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Saint Charles for you!
When is the best time to visit Saint Charles?
If you want the joy of a fun-filled trip in peak season, visit Saint Charles during February, April and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Saint Charles?
Based on historic data is usually the cheapest month to visit Saint Charles. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Saint Charles?
There are multiple hotels in Saint Charles that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Saint Charles. We have plenty of kid-friendly hotels in Saint Charles to choose from on Travelocity!
Why book a hotel in Saint Charles through Travelocity?
Because we have the top hotels in Saint Charles! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Saint Charles on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Saint Charles hotel reviews by fellow wanderers

Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Always our go to in Des moines"
A verified traveler stayed at Home2 Suites by Hilton Des Moines at Drake University
Home2 Suites by Hilton Des Moines at Drake University
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