Explore 7 Luxury Hotels in O'Fallon

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Best Luxury Hotels in O'Fallon

Extended Stay America Select Suites - St. Louis - O' Fallon, IL

Extended Stay America Select Suites - St. Louis - O' Fallon, IL

154 Regency Park O'Fallon IL
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $121 total per night from Jun 14 to Jun 15
$121 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area, laundry facilities, and barbecue grills are also on ...
7.6/10 Good! (898 reviews)
"The freezer in our room was disgusting."

Reviewed on Jun 7, 2026

Opens in a new windowExtended Stay America Select Suites - St. Louis - O' Fallon, IL
Quality Inn O'Fallon IL - St. Louis

Quality Inn O'Fallon IL - St. Louis

1409 W US 50 O'Fallon IL
Fully refundable
$76 nightly
The price is $87 total per night from Jun 14 to Jun 15
$87 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7.4/10 Good! (1,005 reviews)
"Staff at check in was not educated in how to process hotels.com."

Reviewed on Jun 8, 2026

Opens in a new windowQuality Inn O'Fallon IL - St. Louis
Sleep Inn O'Fallon near I-64

Sleep Inn O'Fallon near I-64

140 Venita Dr O'Fallon IL
Fully refundable
$76 nightly
The price is $87 total per night from Jun 15 to Jun 16
$87 total
Jun 15 - Jun 16
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
7/10 Good! (966 reviews)
"This hotel was one of the most disgusting places I have stayed. I saw that it wasn't much more to upgrade to a king bed and a large tub. Upgraded, get to the room and the tub/shower is so disgusting I literally chose not to shower over stepping into that shower. Overall, the room was disgusting. ..."

Reviewed on Jun 2, 2026

Opens in a new windowSleep Inn O'Fallon near I-64
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $65 total per night from Jun 15 to Jun 16
$65 total
Jun 15 - Jun 16
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
6.8/10 (1,005 reviews)
"I checked into the room at 6pm and immediately noticed several large termites dead in the bathtub and a couple around the toilet, I turned on the water and washed them down. A couple hours later upon entering the bathroom there were several more of them in the tub yet again. I proceeded to order ..."

Reviewed on Jun 6, 2026

Opens in a new windowSuper 8 by Wyndham O'Fallon
Comfort Inn & Suites O'Fallon - St. Louis Area

Comfort Inn & Suites O'Fallon - St. Louis Area

116 Regency Park O'Fallon IL
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $95 total per night from Jun 9 to Jun 10
$95 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
6.4/10 (150 reviews)
"The comforter had stains. Breakfast was set up with no care given to it. The front guest person was at the desk sleeping both evenings I came in. I mean you get what you pay for."

Reviewed on May 31, 2026

Opens in a new windowComfort Inn & Suites O'Fallon - St. Louis Area
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

136 Regency Park O'Fallon IL
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
5.8/10 (1,002 reviews)
"The room was disgusting, you walked on the floor and it just felt sticky. It smelled of urine in the room, there was stuff on the walls in the bathroom, and furniture broke in the room highly disappointed. You could jiggle the door and open it even with the deadbolt not a safe place to stay."

Reviewed on Jun 7, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
Baymont by Wyndham O'Fallon St. Louis Area

Baymont by Wyndham O'Fallon St. Louis Area

1320 Park Plaza Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $72 total per night from Jun 14 to Jun 15
$72 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
5.6/10 (486 reviews)
"Last minute stopped only thing we could find and very disappointed after what we paid. Had very bad odor then walked to elevator and there was beer cans. Not cleaned then the worst when we got to the room the covers had a huge yellow stain."

Reviewed on Jun 7, 2026

Opens in a new windowBaymont by Wyndham O'Fallon St. Louis Area
Don't see what you're looking for?
See all available properties in O'Fallon
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in O'Fallon

5 star hotels in O'Fallon

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
$355 nightly
The price is $415 total per night from Jun 14 to Jun 15
$415 total
Jun 14 - Jun 15
Total with taxes and fees
9.4/10 Exceptional! (1,004 reviews)

O'Fallon Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the O'Fallon luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in O'Fallon to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in O'Fallon will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in O'Fallon, and plan your next opulent escape.


O'Fallon hotels essential information

Accommodation
1,401 hotels
Lowest Price
$65
Highest Price
$415
Popular hotels
Super 8 by Wyndham O'Fallon, La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis, Quality Inn O'Fallon IL - St. Louis, Baymont by Wyndham O'Fallon St. Louis Area, Sleep Inn O'Fallon near I-64, Comfort Inn & Suites O'Fallon - St. Louis Area, Extended Stay America Select Suites - St. Louis - O' Fallon, IL

Popular Luxury Stays in O'Fallon

Recent O'Fallon Hotel Reviews By Fellow Wanderers

Explore More Ways to Travel with Travelocity