Explore 7 Luxury Hotels in O'Fallon

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Best Luxury Hotels in O'Fallon

Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

1409 W US 50 O'Fallon IL
Fully refundable
$68 nightly
The price is $78 total per night from Nov 23 to Nov 24
$78 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7.4/10 Good! (1,000 reviews)
"I left my backpack in the lobby last Friday am, have emailed through Expedia a request to call me, or give me their number so that I can call direct, ask them to send it to me and pay them for their time and expenses. No one will contact, nor can I figure any way out to get their number. Important ..."

Reviewed on Oct 27, 2026

Opens in a new windowQuality Inn O'Fallon - St. Louis - Shiloh
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL
$52 nightly
The price is $60 total per night from Nov 8 to Nov 9
$60 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Opens in a new windowSuper 8 by Wyndham O'Fallon
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

136 Regency Park O'Fallon IL
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $75 total per night from Nov 3 to Nov 4
$75 total
Nov 3 - Nov 4
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Opens in a new windowLa Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
Baymont by Wyndham O'Fallon St. Louis Area

Baymont by Wyndham O'Fallon St. Louis Area

1320 Park Plaza Drive O'Fallon IL
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Opens in a new windowBaymont by Wyndham O'Fallon St. Louis Area
Sleep Inn O'Fallon near I-64

Sleep Inn O'Fallon near I-64

140 Venita Dr O'Fallon IL
Fully refundable
$60 nightly
The price is $68 total per night from Nov 4 to Nov 5
$68 total
Nov 4 - Nov 5
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Opens in a new windowSleep Inn O'Fallon near I-64
Comfort Inn & Suites O'Fallon - St. Louis Area

Comfort Inn & Suites O'Fallon - St. Louis Area

116 Regency Park O'Fallon IL
Fully refundable
$60 nightly
The price is $69 total per night from Nov 4 to Nov 5
$69 total
Nov 4 - Nov 5
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Opens in a new windowComfort Inn & Suites O'Fallon - St. Louis Area
Extended Stay America Select Suites - St. Louis - O' Fallon, IL

Extended Stay America Select Suites - St. Louis - O' Fallon, IL

154 Regency Park O'Fallon IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $108 total per night from Nov 9 to Nov 10
$108 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area, laundry facilities, and barbecue grills are also on ...
Opens in a new windowExtended Stay America Select Suites - St. Louis - O' Fallon, IL
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More 4 star hotels in O'Fallon

5 star hotels in O'Fallon

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
$375 nightly
The price is $438 total per night from Nov 3 to Nov 4
$438 total
Nov 3 - Nov 4
Total with taxes and fees
9.4/10 Exceptional! (1,002 reviews)

O'Fallon Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the O'Fallon luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in O'Fallon to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in O'Fallon will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in O'Fallon, and plan your next opulent escape.


O'Fallon hotels essential information

Accommodation
1,464 hotels
Lowest Price
$60
Highest Price
$438
Popular hotels
Super 8 by Wyndham O'Fallon, La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis, Quality Inn O'Fallon - St. Louis - Shiloh, Baymont by Wyndham O'Fallon St. Louis Area, Sleep Inn O'Fallon near I-64, Comfort Inn & Suites O'Fallon - St. Louis Area, Extended Stay America Select Suites - St. Louis - O' Fallon, IL

Popular Luxury Stays in O'Fallon

Recent O'Fallon Hotel Reviews By Fellow Wanderers