Explore 40 Luxury Hotels in Knoxville

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Best Luxury Hotels in Knoxville

La Quinta Inn & Suites by Wyndham Loudon

La Quinta Inn & Suites by Wyndham Loudon

12400 Highway 72 N Loudon TN
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $121 total per night from Dec 13 to Dec 14
$121 total
Dec 13 - Dec 14
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
9/10 Wonderful! (1,007 reviews)
"Nice, modern, clean hotel in good location with friendly staff and nice breakfast."

Reviewed on Nov 10, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Loudon
Quality Inn Knoxville West Cedar Bluff

Quality Inn Knoxville West Cedar Bluff

309 N Peters Rd Knoxville TN
Fully refundable
$72 nightly
The price is $85 total per night from Dec 13 to Dec 14
$85 total
Dec 13 - Dec 14
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the express ...
8/10 Very Good! (423 reviews)
"Overall, this hotel worked well for a short weekend getaway. The highlight was definitely the cleanliness, the room was spotless upon arrival, which made for a comfortable base while visiting Knoxville. There were a few minor drawbacks to keep in mind. There was no iron available in the room, no ..."

Reviewed on Nov 9, 2026

Opens in a new windowQuality Inn Knoxville West Cedar Bluff
THE TENNESSEAN Hotel

THE TENNESSEAN Hotel

531 Henley Street Knoxville TN
Fully refundableReserve now, pay when you stay
$178 nightly
The price is $210 total per night from Nov 22 to Nov 23
$210 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet ...
Opens in a new windowTHE TENNESSEAN Hotel
Crowne Plaza Knoxville Downtown University by IHG

Crowne Plaza Knoxville Downtown University by IHG

401 W Summit Hill Dr Knoxville TN
Fully refundable
$122 nightly
The price is $144 total per night from Nov 22 to Nov 23
$144 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowCrowne Plaza Knoxville Downtown University by IHG
Hilton Knoxville

Hilton Knoxville

501 W Church Ave Knoxville TN
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $130 total per night from Nov 25 to Nov 26
$130 total
Nov 25 - Nov 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Opens in a new windowHilton Knoxville
Days Inn by Wyndham Knoxville East

Days Inn by Wyndham Knoxville East

5423 Asheville Hwy Knoxville TN
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $68 total per night from Nov 25 to Nov 26
$68 total
Nov 25 - Nov 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Opens in a new windowDays Inn by Wyndham Knoxville East
Best Western Knoxville Suites - Downtown

Best Western Knoxville Suites - Downtown

5317 Pratt Rd Knoxville TN
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $113 total per night from Nov 16 to Nov 17
$113 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like full breakfast and free self parking. A 24-hour business center, free WiFi ...
Opens in a new windowBest Western Knoxville Suites - Downtown
Hampton Inn & Suites-Knoxville/North I-75

Hampton Inn & Suites-Knoxville/North I-75

5411 Pratt Rd. Knoxville TN
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $118 total per night from Nov 29 to Nov 30
$118 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A 24-hour ...
Opens in a new windowHampton Inn & Suites-Knoxville/North I-75
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More 4 star hotels in Knoxville

Knoxville Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Knoxville luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Knoxville to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Knoxville will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Knoxville, and plan your next opulent escape.


Knoxville hotels essential information

Accommodation
1,121 hotels
Lowest Price
$68
Highest Price
$210
Popular hotels
THE TENNESSEAN Hotel, Crowne Plaza Knoxville Downtown University by IHG, Hilton Knoxville, Days Inn by Wyndham Knoxville East, Best Western Knoxville Suites - Downtown, Quality Inn Knoxville West Cedar Bluff, Hampton Inn & Suites-Knoxville/North I-75, La Quinta Inn & Suites by Wyndham Loudon

Popular Luxury Stays in Knoxville

Recent Knoxville Hotel Reviews By Fellow Wanderers