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Top hotels in Historic Southwest

The Upper Rooms

The Upper Rooms

Rochester MN
This apartment features laundry facilities.
"Loved that we had our own parking spot. We were able to walk to most places downtown in about 15 minutes. Was nice and clean, beds were comfortable. Plenty of space to spread out."

Reviewed on May 2, 2026

Opens in a new windowThe Upper Rooms
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
Fully refundable
$126 nightly
The price is $145 total per night from Jun 20 to Jun 21
$145 total
Jun 20 - Jun 21
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Extremely slow & impersonal front desk. Messed up our keys & had to spend 10 minutes getting it resolved. Very competent & kind breakfast server & decent breakfast options. Parking, shuttle & location all good."

Reviewed on Jun 2, 2026

Opens in a new windowEVEN Hotel Rochester - Mayo Clinic Area by IHG
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $172 total per night from Jun 5 to Jun 6
$172 total
Jun 5 - Jun 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"Found a bed bug"

Reviewed on Jun 3, 2026

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

3 out of 5
225 S Broadway Rochester MN
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $141 total per night from Jun 28 to Jun 29
$141 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free WiFi. There's a hot tub on site, and laundry facilities ...
"Coming to visit the Mayo Clinic was a difficult journey, yet every single employee we had contact with was amazing! We felt well cared for and our every need was met! The breakfast was wonderful each day; the front desk folks were always helpful and thoughtful. We greatly appreciated the rides to ..."

Reviewed on May 28, 2026

Opens in a new windowHilton Garden Inn Rochester Downtown, MN
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$112 nightly
The price is $129 total per night from Jun 20 to Jun 21
$129 total
Jun 20 - Jun 21
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"This is our go to place whenever we have appt at Mayo."

Reviewed on Jun 3, 2026

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Jun 6 to Jun 7
$131 total
Jun 6 - Jun 7
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
"Came up for a Mayo visit. I selected this location because they advertised sound"

Reviewed on Jun 3, 2026

Opens in a new windowCenterstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$145 nightly
The price is $167 total per night from Jun 30 to Jul 1
$167 total
Jun 30 - Jul 1
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"1"

Reviewed on Jun 3, 2026

Opens in a new windowKahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $178 total per night from Jun 14 to Jun 15
$178 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"Front staff was very friendly and helpful - appreciated the early check-in. Staff we met in the hall were friendly and welcoming."

Reviewed on Jun 3, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $97 total per night from Jun 7 to Jun 8
$97 total
Jun 7 - Jun 8
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"Cost-effective lodging. Room, facility, staff, & breakfast are adequate. I would go again if need an economical place to stay."

Reviewed on Jun 4, 2026

Opens in a new windowMed City Inn & Suites - Mayo Clinic Area
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Historic Southwest Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Historic Southwest area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Historic Southwest to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Historic Southwest are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Historic Southwest hotel reviews by fellow wanderers