Find a Hotel in Historic Southwest

Start date: Check-in selected.
To Date
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top hotels in Historic Southwest

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
Fully refundable
$116 nightly
The price is $133 total per night from Jan 24 to Jan 25
$133 total
Jan 24 - Jan 25
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Great

Reviewed on Jan 9, 2026

Opens in a new windowEVEN Hotel Rochester - Mayo Clinic Area by IHG
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $161 total per night from Feb 1 to Feb 2
$161 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Breakfast to go was offered for the volleyball players.

Reviewed on Jan 4, 2026

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

3 out of 5
225 S Broadway Rochester MN
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $123 total per night from Jan 30 to Jan 31
$123 total
Jan 30 - Jan 31
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free WiFi. There's a hot tub on site, and laundry facilities ...
pros - clean room, friendly and helpful staff cons - all paper drinking cups, hot water temp and pressure in shower/bath a bit low, charge for water in room

Reviewed on Jan 4, 2026

Opens in a new windowHilton Garden Inn Rochester Downtown, MN
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$76 nightly
The price is $88 total per night from Jan 30 to Jan 31
$88 total
Jan 30 - Jan 31
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Great stay, convenient and Crave being attached was an added bonus.

Reviewed on Jan 9, 2026

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
Aspen Suites

Aspen Suites

3 out of 5
1211 2nd Street Rochester MN
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $175 total per night from Jan 18 to Jan 19
$175 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Yes, everything was wonderful. Appreciate that it is right across the street from St. Mary’s.

Reviewed on Jan 9, 2026

Opens in a new windowAspen Suites
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $158 total per night from Jan 15 to Jan 16
$158 total
Jan 15 - Jan 16
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
Good food and bar

Reviewed on Jan 3, 2026

Opens in a new windowCenterstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from Jan 14 to Jan 15
$146 total
Jan 14 - Jan 15
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
No free breakfast

Reviewed on Jan 8, 2026

Opens in a new windowKahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $89 total per night from Jan 18 to Jan 19
$89 total
Jan 18 - Jan 19
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
Good value for what you get. Clean room, comfortable bed, nice location, and good breakfast. Pool / hot tub area could use better ventilation and updating.

Reviewed on Jan 4, 2026

Opens in a new windowAmericInn by Wyndham Rochester Near Mayo Clinic
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $152 total per night from Jan 13 to Jan 14
$152 total
Jan 13 - Jan 14
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
We enjoy staying at Kahler Inn & Suites. So nice to be so close to Mayo Clinic. You don't have to go outside. You can walk from the hotel tp Mayo. Everyone is so friendly and the breakfast is great!

Reviewed on Jan 9, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
Don't see what you're looking for?
See all available properties in Historic Southwest
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Historic Southwest Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Historic Southwest area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Historic Southwest to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Historic Southwest are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Historic Southwest hotel reviews by fellow wanderers