Find a Hotel in Historic Southwest
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Top hotels in Historic Southwest

EVEN Hotel Rochester - Mayo Clinic Area by IHG
"Clean!"
Reviewed on Jul 4, 2026

Hyatt House Rochester/Mayo Clinic Area
"The good: Clean room, comfortable bed, very kind staff, great breakfast, convenient parking garage. The bad: Wall outlets in the room were all very loose and nothing would stay plugged in (the weight of the plug would cause it to fall out). There were no bath towels in the room (I assume the cleaning ..."
Reviewed on Jul 1, 2026

Hilton Garden Inn Rochester Downtown, MN
"Room has quite a bit of wear for the price. Location good with skywalk access to Civic Center"
Reviewed on Jul 3, 2026

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
"The staff were very friendly and helpful! Enjoyed having a variety of options for breakfast. The room fridge didn’t keep our food very cold and water temperature for showering didn’t get very hot."
Reviewed on Jul 3, 2026

Kahler Grand Hotel
"Staff were always friendly and helpful. Hot tub and pool were a plus for me. Did not need to go outside for any of my appointments at Mayo Clinic. Easy access to everything. Lord Essex restaurant has a great breakfast. Highly recommend the Kahler Grand Hotel."
Reviewed on Jul 3, 2026

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
"Great pool fun and we loved the arcade games!"
Reviewed on Jul 3, 2026

Kahler Inn and Suites - Mayo Clinic Area
"Room was clean. Staff was hopeful. Complementary breakfast was good. Parking space appreciated and rate was not terrible. However, it is a very tight lot."
Reviewed on Jul 3, 2026

Med City Inn & Suites - Mayo Clinic Area
"it was nice for what we stayed for"
Reviewed on Jul 3, 2026

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
"My go to hotel in Rochester now. Always excellent in all areas"
Reviewed on Jul 1, 2026
Historic Southwest Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Historic Southwest area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Historic Southwest to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Historic Southwest are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Historic Southwest hotel reviews by fellow wanderers

AmericInn by Wyndham Rochester Near Mayo Clinic
"M"
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