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Top hotels in Historic Southwest

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Nov 27 to Nov 28
$160 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"If you want a full breakfast you'd better get up right when they serve because if they run out of things they will yell you like they told me, no, we will not be putting out more. It was 30 mn before the end if breakfast and there were no potatoes, 5 pieces left which I took 2 because there was a ..."

Reviewed on Oct 29, 2026

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

3 out of 5
225 S Broadway Rochester MN
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Nov 13 to Nov 14
$136 total
Nov 13 - Nov 14
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free WiFi. There's a hot tub on site, and laundry facilities ...
"So convenient to walk to convention center. Comfortable rooms."

Reviewed on Nov 1, 2026

Opens in a new windowHilton Garden Inn Rochester Downtown, MN
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$103 nightly
The price is $119 total per night from Nov 14 to Nov 15
$119 total
Nov 14 - Nov 15
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"This was a nice hotel with a great location. There were several bars and restaurants within walking distance."

Reviewed on Oct 31, 2026

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $183 total per night from Nov 26 to Nov 27
$183 total
Nov 26 - Nov 27
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"We will stay at this hotel again. Bed very comfortable!"

Reviewed on Nov 1, 2026

Opens in a new windowKahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $170 total per night from Nov 13 to Nov 14
$170 total
Nov 13 - Nov 14
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"Good value! Perfect for Mayo Clinic care location. PET and family friendly. Good Asian food restaurant in the building and breakfast. I would stay there again even if having only fun on the agenda for Rochester, MN"

Reviewed on Oct 31, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $92 total per night from Dec 1 to Dec 2
$92 total
Dec 1 - Dec 2
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"It was nice and quite"

Reviewed on Oct 31, 2026

Opens in a new windowMed City Inn & Suites - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Nov 6 to Nov 7
$131 total
Nov 6 - Nov 7
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
Opens in a new windowCenterstone Plaza Hotel Soldiers Field - Mayo Clinic Area
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $87 total per night from Nov 8 to Nov 9
$87 total
Nov 8 - Nov 9
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
Opens in a new windowAmericInn by Wyndham Rochester Near Mayo Clinic
Brentwood Inn & Suites

Brentwood Inn & Suites

2.5 out of 5
123 Fourth Ave. NW Rochester MN
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $138 total per night from Nov 2 to Nov 3
$138 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
Opens in a new windowBrentwood Inn & Suites
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Historic Southwest Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Historic Southwest area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Historic Southwest to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Historic Southwest are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Historic Southwest hotel reviews by fellow wanderers

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

5 out of 5
Posted 13 hours ago
Travelocity Verified Review
"So convenient to walk to convention center. Comfortable rooms."
A verified traveler stayed at Hilton Garden Inn Rochester Downtown, MN
Hilton Garden Inn Rochester Downtown, MN