Explore 9 Luxury Hotels in Downtown Cincinnati

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Best Luxury Hotels in Downtown Cincinnati

Hyatt Regency Cincinnati

Hyatt Regency Cincinnati

151 West Fifth Street Cincinnati OH
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $202 total per night from Nov 16 to Nov 17
$202 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,659 reviews)
"Great hotel"

Reviewed on Nov 11, 2026

Opens in a new windowHyatt Regency Cincinnati
The Westin Cincinnati

The Westin Cincinnati

21 E 5th St Cincinnati OH
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $154 total per night from Nov 22 to Nov 23
$154 total
Nov 22 - Nov 23
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling for business? Take advantage of the business center, express check-out, and conference space. ...
8.8/10 Excellent! (1,464 reviews)
"Hotel is outdated. No food options past 9p"

Reviewed on Nov 10, 2026

Opens in a new windowThe Westin Cincinnati
21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

609 Walnut St Cincinnati OH
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $187 total per night from Dec 6 to Dec 7
$187 total
Dec 6 - Dec 7
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
8.6/10 Excellent! (1,059 reviews)
"We absolutely loved our time at the 21c in Cincinnati. I had no idea when I booked it that the hotel is also a very funky art gallery - my favorite kind! We had so much fun checking out the art across several floors. The room was comfortable and clean. The location was fantastic, walkable to all ..."

Reviewed on Nov 10, 2026

Opens in a new window21c Museum Hotel Cincinnati
The Cincinnatian Hotel Curio Collection by Hilton

The Cincinnatian Hotel Curio Collection by Hilton

601 Vine Street Cincinnati OH
Fully refundableReserve now, pay when you stay
$145 nightly
The price is $172 total per night from Dec 5 to Dec 6
$172 total
Dec 5 - Dec 6
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
7.8/10 Good! (1,001 reviews)
"Nice and roomy for a big family convenient close to the beach close to South Beach real roomie only thing that I was missing that was it wasn’t a garbage cans in the rooms but other than that I enjoyed my stay close to the stores close to the beach"

Reviewed on Nov 11, 2026

Opens in a new windowThe Cincinnatian Hotel Curio Collection by Hilton
Hilton Cincinnati Netherland Plaza

Hilton Cincinnati Netherland Plaza

35 W 5th St Cincinnati OH
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $126 total per night from Nov 22 to Nov 23
$126 total
Nov 22 - Nov 23
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and A 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public ...
Opens in a new windowHilton Cincinnati Netherland Plaza
Renaissance Cincinnati Downtown Hotel

Renaissance Cincinnati Downtown Hotel

36 East Fourth Street Cincinnati OH
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $214 total per night from Nov 28 to Nov 29
$214 total
Nov 28 - Nov 29
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Opens in a new windowRenaissance Cincinnati Downtown Hotel
Residence Inn by Marriott Cincinnati Downtown/The Phelps

Residence Inn by Marriott Cincinnati Downtown/The Phelps

506 East 4th Street Cincinnati OH
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $178 total per night from Nov 30 to Dec 1
$178 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowResidence Inn by Marriott Cincinnati Downtown/The Phelps
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Downtown Cincinnati

5 star hotels in Downtown Cincinnati

The Lytle Park Hotel, Autograph Collection

The Lytle Park Hotel, Autograph Collection

311 PIKE ST Cincinnati OH
$296 nightly
The price is $353 total per night from Nov 25 to Nov 26
$353 total
Nov 25 - Nov 26
Total with taxes and fees

Downtown Cincinnati Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Downtown Cincinnati luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Downtown Cincinnati to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Downtown Cincinnati will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Downtown Cincinnati, and plan your next opulent escape.


Downtown Cincinnati hotels essential information

Accommodation
418 hotels
Lowest Price
$126
Highest Price
$353
Popular hotels
21c Museum Hotel Cincinnati, The Cincinnatian Hotel Curio Collection by Hilton, Hilton Cincinnati Netherland Plaza, Hyatt Regency Cincinnati, The Westin Cincinnati, Renaissance Cincinnati Downtown Hotel, Residence Inn by Marriott Cincinnati Downtown/The Phelps

Popular Luxury Stays in Downtown Cincinnati

Recent Downtown Cincinnati Hotel Reviews By Fellow Wanderers