
Deals on vacations and trips to Downtown South San Francisco

Downtown South San Francisco flight + hotel vacation packages
Price found within the past 48 hours. Click for updated prices.

Union Square Plaza Hotel
Union Square
Save 100% on your flight
Price was $375, price is now $222 per person
$222
per person
Jan 22 - Jan 25
found 11 hours ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
This hotel features free WiFi in public areas, luggage storage, and concierge services. Staff at the 24-hour front desk can provide around-the-clock assistance.

San Carlos Inn
Save 100% on your flight
Price was $832, price is now $426 per person
$426
per person
Feb 5 - Feb 9
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to San Francisco (SFO)
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Express check-out is also provided.

Hotel Riu Plaza Fisherman's Wharf
Fisherman's Wharf
Price was $2,570, price is now $1,339 per person
$1,339
per person
Feb 5 - Feb 9
found 4 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to San Francisco (SFO)
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the 24-hour gym and free buffet breakfast each morning.

The Grove Inn
Western Addition
Save 100% on your flight
Price was $1,473, price is now $779 per person
$779
per person
Feb 5 - Feb 9
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to San Francisco (SFO)
Free WiFi in public areas, a communal living room, and express check-in are available at this hotel. A business center, express check-out, and luggage storage are also on offer.

Bay Landing San Francisco Airport Hotel
Bayfront
Save 100% on your flight
Price was $1,052, price is now $570 per person
$570
per person
Feb 5 - Feb 9
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to San Francisco (SFO)
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Business travelers can take advantage of the free WiFi in public areas. Enjoy the gym and conveniences like a 24-hour front desk and laundry facilities.
Top Downtown South San Francisco hotels deals

Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$119 nightly
The price is $140 total per night
$140 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a bar/lounge on site, and a 24-hour front desk and laundry facilities are also provided.
Pool
Free WiFi

Hyatt Regency San Francisco
5 Embarcadero Center San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$208 nightly
The price is $245 total per night
$245 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A coffee shop, a snack bar/deli, and a grocery/convenience store are also on offer.
Pet friendly
Free WiFi

DoubleTree by Hilton Hotel Berkeley Marina
200 Marina Blvd Berkeley CA
Free Cancellation
Reserve now, pay when you stay
$139 nightly
The price is $160 total per night
$160 total
Nov 27 - Nov 28
Total with taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the indoor pool, bar/lounge, and laundry facilities.
Pool
Hot Tub

Hotel Riu Plaza Fisherman's Wharf
2500 Mason St San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$144 nightly
The price is $170 total per night
$170 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the 24-hour gym and free buffet breakfast each morning.
Pool
Breakfast included

Best Western Plus Grosvenor Airport Hotel
380 S Airport Boulevard South San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$91 nightly
The price is $108 total per night
$108 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Self parking, a library, and express check-in are also offered.
Breakfast included
Free airport shuttle

Fairmont San Francisco
950 Mason Street Atop Nob Hill San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$215 nightly
The price is $253 total per night
$253 total
Nov 23 - Nov 24
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, and valet parking. Relax with a drink at one of the 2 bars/lounges and enjoy the sauna.
Spa
Pet friendly
Don't see what you're looking for?
See all available properties in Downtown South San Francisco
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Golden Gate Bridge
4.5/5(7,244 reviews)
Cars trundle across it and ships sail under it, but the best way to experience this iconic bridge is on foot.

Pier 39
4.5/5(6,817 reviews)
This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.

Moscone Convention Center
4/5(598 reviews)
During your trip, find out what's happening at Moscone Convention Center, a top convention center in San Francisco. Discover the fascinating museums and shops in this vibrant area.
Frequently asked questions
Photos of local treasures
Browse Downtown South San Francisco vacation photos for more inspiration
