Deals on vacations and trips to Cayo Santa Maria

Save when you book Cayo Santa Maria package deals

Choose two or more items and save on your trip:

Cayo Santa Maria flight + hotel vacation packages

Mayfair House Hotel & Garden
 Divina Luxury Hotel
Icon Residences By Sunnyside Hotel and Resorts
The Retreat Collection at 1 Hotel & Homes South Beach
1 Hotel South Beach
Prices and availability subject to change. Additional terms may apply.

Top Cayo Santa Maria hotels deals

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much are vacation packages to Cayo Santa Maria?
Exciting adventures await in Cayo Santa Maria, with Travelocity vacation packages starting from as low as $547. Offering both hotels and flights, these amazing deals make it super simple to visit more of our wonderful planet.
Where can I get the best vacation package deals for Cayo Santa Maria?
You’ll discover a tempting selection of Cayo Santa Maria package deals on Travelocity. With 400 partner airlines and 1,000,000 properties across the globe, crafting your ultimate getaway will be a breeze.
Why should I book my Cayo Santa Maria vacation bundle with Travelocity?
We offer round-the-clock support, superb service and a Price Match Guarantee. Life is all about the journey — and we have enticing destinations for you to journey to all across the globe. Wander with us and your wallet will thank you for it.
Can I save on my Cayo Santa Maria car rental if I book it with my hotel or flight?
You sure can with our Cayo Santa Maria vacation packages. With one of these, there are plenty of ways to stretch your budget further. Combine any two or more car, hotel, flight and tour bookings and watch your savings start to add up. With your own set of wheels, all the popular attractions around Cayo Santa Maria are a fun road trip away.
What is the best time of year to go to Cayo Santa Maria?
If you’re eager to avoid expensive airfares, tourist crowds and booked-out hotels, organize your getaway outside of January, May and July. The quietest time to be in Cayo Santa Maria is February, November and December. You’ll find hotel prices are the highest in and the cheapest in .