Beginning of main content
Save up to $986 | Book Flight + Hotel at the same time^
Save up to $986 | Book Flight + Hotel at the same time^
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5
Save up to $986 | Book Flight + Hotel at the same time^

Cayo Santa Maria Vacations

Cayo Santa Maria Vacations

Unwittingly stumbling upon a new place is exactly what makes travel so special, But of course, it never hurts to understand a bit about the area before you take off. We'll fill you in on a few basics about Cayo Santa Maria.

You'll find it in Cuba, and just 4 miles (6 kilometers) away from Cayo Ensenachos.

Cayo Santa Maria Vacation Packages

Booking a hotel and airfare bundle via Travelocity is the simplest way to save heaps on your Cayo Santa Maria getaway. And also, you can pick from more than 400 partner airlines and 665,000 accommodations.

From flights and accommodations to experiences and car rentals, we can promise you 24/7 personal assistance via our Customer 1st Guarantee. Seen a better deal elsewhere? We'll meet the price and refund the difference^.

There's no way to tell when an emergency will arise. However, if you purchase a deal, we guarantee that there'll be no cancellation charges from us. And so long as you get in quick, most accommodations won't charge you either^.

Where do you fly into for Cayo Santa Maria?

Nothing comes close to landing in a completely new place. If you're hopping on a plane to Cayo Santa Maria, there's every chance you'll be stepping out into Maximo Gomez Airport (AVI). It's around 45 miles (72 kilometers) to the south of the main streets. Pick up your suitcase and get set to kick-start your vacation!

Can I rent a car in Cayo Santa Maria?

Grab a rental vehicle via Travelocity for your trip to Cayo Santa Maria. You're sure to stumble upon some amazing sights while you're cruising down the road.

Places to visit in Cayo Santa Maria

Make your way over the water to Cayo Los Brujas, an accessible tourist attraction. Seeking some more ideas? Cayo Santa Maria Dolphinarium is a fun place where you can see all kinds of marine life up close and enjoy some of the displays.

Places to Visit Near Cayo Santa Maria

If you have explored the best of Cayo Santa Maria with time to spare, don't fret! Just 35 miles (56 kilometers) away is Caibarien, and you certainly won't be bored here. Caibarien Beach is a fantastic place to learn the culture of the area. San Juan Bautista de Remedios Museum and the Galería del Arte Carlos Enríquez are more fantastic spots to visit. Sancti Spiritus is another nearby destination situated just 55 miles (89 kilometers) away. Travelers come here for Serafn Sanchez Square, Iglesia Parroquial Mayor and the Museo Provincial.

^Terms and conditions apply.

Top Cayo Santa Maria Hotels Deals

Grand Memories Santa Maria - All Inclusive $108
Grand Memories Santa Maria - All Inclusive

Grand Memories Santa Maria - All Inclusive

Municipio Caibarien, Cayo Santa Maria, Villa Clara
     
    3.5 out of 5.0 Stars

    This all-inclusive property includes 5 restaurants, an outdoor pool, and an outdoor tennis court. There's fun for all ages with a free kid's club and a children's pool, and supervised childcare is an added bonus. Relax with a drink at the beach bar and enjoy free perks like buffet breakfast and free self parking.

    Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive $126
    Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive

    Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive

    Cayo Santa Maria, Cayo Santa Maria, Villa Clara
       
      3.5 out of 5.0 Stars

      This all-inclusive property features 5 restaurants, 2 outdoor tennis courts, and an outdoor pool. Enjoy the health club and free perks like buffet breakfast and free self parking. A beach bar, a 24-hour front desk, and a poolside bar are also provided.

      Villa Gaviota Cayo Coco Get Rates
      Villa Gaviota Cayo Coco

      Villa Gaviota Cayo Coco

      Ciego de Avila, Cayo Santa Maria
         
        0.0 out of 5.0 Stars

        Situated in Cayo Santa Maria, this hotel is 3.4 mi (5.5 km) from Cayo Santa Maria Dolphinarium and 5.5 mi (8.9 km) from Playa Las Gaviotas.

        Hotel Las Salinas Plaza & Spa Get Rates
        Hotel Las Salinas Plaza & Spa

        Hotel Las Salinas Plaza & Spa

        Cayo las Brujas, Villa Clara, Cayo Las Brujas
           
          3.5 out of 5.0 Stars

          A full-service spa, 4 restaurants, and an outdoor pool are all featured at this hotel. Relax with a drink at the poolside bar and enjoy free perks like continental breakfast and free self parking. A bar/lounge, a 24-hour front desk, and a terrace are also provided.

          Hotel Grand Aston Cayo LAS Brujas Adults Section Get Rates
          Hotel Grand Aston Cayo LAS Brujas Adults Section

          Hotel Grand Aston Cayo LAS Brujas Adults Section

          Las Dunas 5, Cayo Las Brujas, Villa Clara
             
            5.0 out of 5.0 Stars

            A full-service spa and a restaurant are featured at this luxury property. A hair salon is also provided.

            ^Savings based on all package bookings made with Flight + Hotel on Travelocity.com from January 1, 2018 to December 31, 2018, as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.

            *Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.