Cairo Vacation Packages 2026 from $412

Cairo flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Holiday Inn Express Fort Campbell-Oak Grove by IHG

$412

per person

Dec 5 - Dec 8

found 21 hours ago

Roundtrip non-stop flight included

Portland (PDX) to Paducah (PAH)

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Candlewood Suites Fort Campbell - Oak Grove by IHG

$425

per person

Dec 5 - Dec 8

found 21 hours ago

Roundtrip non-stop flight included

Portland (PDX) to Paducah (PAH)

This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy free perks like free self parking and a casino shuttle.

Top Cairo hotels deals

Quality Inn Cairo I-57

13201 Kessler Road Cairo IL

Free Cancellation

$69 nightly

$76 total

Nov 15 - Nov 16

Total with taxes and fees

This hotel features free WiFi in public areas, free newspapers, and free self parking. Enjoy the free full breakfast each morning. A picnic area is provided and the front desk is staffed around-the-clock.

Breakfast included

Pet friendly

The Riverstone Hotel Charleston-Sikeston

102 Drake St Charleston MO

Free Cancellation

$66 nightly

$74 total

Nov 2 - Nov 3

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 24-hour business center and free internet in public areas. Enjoy the seasonal outdoor pool and conveniences like a 24-hour front desk and laundry facilities.

Pool

Breakfast included

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

Free Cancellation

Reserve now, pay when you stay

$60 nightly

$67 total

Nov 1 - Nov 2

Total with taxes and fees

This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. There's a computer station and multilingual staff can provide around-the-clock assistance.

Breakfast included

Pet friendly

Peaceful secluded cabin located near Horseshoe Lake

Miller City IL

$189 nightly

$200 total

Nov 1 - Nov 2

Total with taxes and fees

This cabin features barbecue grills.

Kitchen

Pet friendly

Cozy cabins on beautiful Horseshoe Lake

Olive Branch IL

$133 nightly

$140 total

Nov 7 - Nov 8

Total with taxes and fees

Stay at this cabin in Alexander County. Enjoy patios, an in-room coffeemaker, and air conditioning.

Air conditioning

Lake view

Charming cottage overlooking Lake Acre

Dongola IL

$263 nightly

$278 total

Nov 6 - Nov 7

Total with taxes and fees

This cabin features a garden, laundry facilities, and barbecue grills.

Kitchen

Washer

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Cairo attractions

Fort Defiance State Park

7.4/10 (15 reviews)

You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area.

See properties

Frequently asked questions

How much are vacation packages to Cairo?

You'll be pleasantly surprised — you can find yourself in Cairo for just $412. Allow Travelocity to save you time and money with our awesome vacation package deals. With hotels, flights and tours all in one place, what are you waiting for?

Where can I get the best vacation package deals for Cairo?

With around 400 partner airlines and 1,000,000 hotels across the world, you can't beat Travelocity. Scroll through our impressive range and create the perfect package deal to Cairo. Doesn't it feel amazing when organizing a trip is that easy?

Why should I book my Cairo vacation package via Travelocity?

Nothing tops the satisfaction of knowing you've bagged the best price around — that's our Price Match Guarantee. Add to that our fantastic range of destinations and 24/7 team of customer service professionals and you've got the formula for a stress-free vacation.

Can I save on my Cairo car rental if I book it with hotels and flights?

With a Cairo vacation package, you can bundle your car, flight and hotel bookings and save some serious money. When you're ready to explore the best of this awesome city, why not make a beeline for Anheuser-Busch Brewery? This popular attraction is 120 mi from Cairo. With your own rental car, you'll be there in the blink of an eye.

Which airport is best for Cairo?

Williamson County Regional Airport (MWA) is 50 mi from downtown and is the beginning point for many memorable experiences. Alternatively, Cape Girardeau Municipal Airport (CGI) is 25 mi away from central Cairo and Barkley Regional Airport (PAH) is 25 mi away from central Cairo.

What is there to do in Cairo?

Click away at the excellent photo opportunities at Fort Defiance State Park, one of the most popular attractions in Cairo. There's a lot more to discover around this exciting city, so make sure you have enough time to visit some of its off-the-beaten-path gems.

Where should I stay when visiting Cairo?

The Quality Inn Cairo I-57 is popular with many visitors. Book soon to avoid missing out.