Deals on vacations and trips to Cairo

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Cairo flight + hotel vacation packages

Regency Inn

Regency Inn

2 out of 5
per person
Jun 14 - Jun 16
Roundtrip non-stop flight included
Grand Rapids (GRR) to Paducah (PAH)
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-out. Enjoy the seasonal outdoor pool and conveniences like a 24-hour front desk and laundry facilities.
AmeriVu Inn & Suites - Gilbertsville

AmeriVu Inn & Suites - Gilbertsville

3 out of 5
per person
Jun 14 - Jun 16
Roundtrip non-stop flight included
Grand Rapids (GRR) to Paducah (PAH)
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Laundry facilities are provided for your convenience.
Days Inn by Wyndham Calvert City

Days Inn by Wyndham Calvert City

2 out of 5
per person
Jun 14 - Jun 16
Roundtrip non-stop flight included
Grand Rapids (GRR) to Paducah (PAH)
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business center and free internet in public areas. There's a seasonal outdoor pool on site, and a 24-hour front desk and a picnic area are also provided.
Super 8 by Wyndham Paducah I-24 Exit 4

Super 8 by Wyndham Paducah I-24 Exit 4

2 out of 5
per person
Jun 14 - Jun 16
Roundtrip non-stop flight included
Grand Rapids (GRR) to Paducah (PAH)
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A picnic area is also provided.
Days Inn by Wyndham Oak Grove/Ft. Campbell

Days Inn by Wyndham Oak Grove/Ft. Campbell

2.5 out of 5
per person
Jun 14 - Jun 16
Roundtrip non-stop flight included
Grand Rapids (GRR) to Paducah (PAH)
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business center. There's a seasonal outdoor pool on site, and a 24-hour front desk and express check-out are also provided.
Prices and availability subject to change. Additional terms may apply.

Top Cairo hotels deals

Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 out of 5
13201 Kessler Road, Cairo, IL
Free Cancellation
Reserve now, pay when you stay
The price is $76 per night
$76
per night
May 19 - May 20
A seasonal outdoor pool, free self parking, and free newspapers are featured at this hotel. Guests will appreciate free perks like full breakfast and WiFi in public areas. A picnic area is provided and the front desk is staffed around-the-clock.
Super 8 by Wyndham Charleston MO

Super 8 by Wyndham Charleston MO

2 out of 5
310 S Story St, Charleston, MO
Free Cancellation
Reserve now, pay when you stay
The price is $64 per night
$64
per night
Apr 25 - Apr 26
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. There's a computer station and multilingual staff can provide around-the-clock assistance.
Quality Inn Charleston I-57

Quality Inn Charleston I-57

2.5 out of 5
102 Drake St, I-57 Exit 10, Charleston, MO
Free Cancellation
Reserve now, pay when you stay
The price is $67 per night
$67
per night
Apr 27 - Apr 28
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business center and free internet in public areas. A safe deposit box is provided and the front desk is staffed around-the-clock.
Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre

The price is $150 per night
$150
per night
May 1 - May 2
This cabin includes a garden and barbecue grills.
Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

The price is $103 per night
$103
per night
Apr 21 - Apr 22
Enjoy a porch, a patio, and a Smart TV. Discover genuine guest reviews for Cozy cabins on beautiful Horseshoe Lake along with the latest prices and availability – book now.
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

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This vacation home includes a garden and barbecue grills.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Image for Fort Defiance State Park

Fort Defiance State Park

4/5(14 reviews)

Explore the great outdoors at Fort Defiance State Park, a lovely green space in Cairo. Stroll along the riverfront or experience the area's entertainment venues.

Fort Defiance State Park

Frequently asked questions

How much are vacation packages to Cairo?
You’ll find an amazing flight and hotel bundle for an affordable $336. With a Travelocity vacation package, an escape to Cairo has never looked more enticing! Save some time and money and get an early start with packing your suitcases.
How long should my Cairo vacation be?
Many people book their hotel for 3 nights in Cairo. But that doesn’t necessarily mean you have to follow suit. How long you stick around really boils down to how much you want to do on your vacation. If you hope to explore every corner of this superb destination, stay another night or two (or even an extra week!).
Where can I get the best vacation package deals for Cairo?
For a fun and affordable package deal to Cairo, book with Travelocity. Choose from 400 partner airlines and 1,000,000 worldwide properties to create the ideal trip — you’re spoiled for choice!
Why should I book my Cairo vacation bundle with Travelocity?
We take the stress out of travel planning. Whether you’re after an amazing new place to wander around or want to ensure you get the best price on offer, we’ve got you covered. Our 24/7 customer support, quality service and Price Match Guarantee mean you can book with confidence with Travelocity.
Can I save money on my Cairo car rental if I book it with a hotel or flight?
Combining your car, flight and hotel into a Cairo vacation package is the best way to score better prices. Plus, having your own set of wheels gives you absolute freedom to make your way to all those landmarks you want to explore. Situated 120 mi from Cairo, Anheuser-Busch Brewery is one place that should feature on your itinerary. Fasten your seat belt and make a day trip of it.
What is the best time of year to go to Cairo?
You can swerve the crowds and save cash in December, January and February, the quietest period to visit. The peak season months of June, July and August are of course busier and more expensive, but there’ll be more happening around Cairo. Organize a hotel in and you’ll get the best value for your dollar. Generally, room rates are dearer in .
Which airport is best for Cairo?
Williamson County Regional Airport (MWA) is popular. You’ll find it approximately 50 mi north of Cairo. Your other options are Cape Girardeau Municipal Airport (CGI) (25 mi away from central Cairo) and Barkley Regional Airport (PAH) (25 mi away from central Cairo).
What is there to do in Cairo?
Snap up the excellent photo-ops at Fort Defiance, one of the most visited attractions in Cairo. There’s a lot more to discover around this exciting city, so give yourself enough time to visit some of its lesser-known sights.
Where should I stay when visiting Cairo?
The Quality Inn Cairo I-57 is popular with many visitors. Book soon to avoid missing out.