Book Hotels in Cairo, MO
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Top Cairo hotels

Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness
Cairo MO
This vacation home featured laundry facilities and barbecue grills.
We were looking for a quiet getaway and disconnect. This was the perfect place do this! We enjoyed our stay and look forward to returning. Highly recommend!
Reviewed on Nov 1, 2025

'grace Place' Clark House on Farm: Shared Hot Tub!
Clark MO
An outdoor pool is featured at this cottage, along with free WiFi in public areas.
Grace Place
Very clean with a wonderful country atmosphere. Perfect size for 1-2 people to share. The farm animals won my heart over!!!!!!!
Reviewed on Aug 18, 2025

Comfort Inn & Suites Moberly
1801 W Outer Rd Moberly MO
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $108 total per night from Dec 18 to Dec 19
$108 total
Dec 18 - Dec 19
Total with taxes and fees
A gym, free self parking, and free newspapers are featured at this hotel. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. A ...
I don’t have too many, if any, complaints about this place. I stayed at a different hotel during this trip and this one was great compared to the other one. This one was a lot more convenient. Breakfast was good.
Reviewed on Oct 21, 2025

Super 8 by Wyndham Moberly MO
300 E Highway 24 Moberly MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Dec 14 to Dec 15
$76 total
Dec 14 - Dec 15
Total with taxes and fees
Free self parking is available and the motel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
Room was clean, bed was very comfortable, service was great, good sized fridge, restaurants nearby (walmart within 1/4 mi and walgreens across the street). Also had a nice electric recliner in the room and nice sized TV. no complaints at all
Reviewed on Oct 28, 2025

Simple Rewards Inn Shelbina
711 North Highway 15, Shelbina, MO
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $90 total per night from Dec 1 to Dec 2
$90 total
Dec 1 - Dec 2
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
The room was clean. The bed, to me, wasn't very comfortable but I do not like to sleep on memory foam mattresses. If you have mobility issues, the toilet was pretty low to the ground. The sink isn't in the bathroom, it was around the corner. The couple at the front desk were very nice. Breakfast ...
Reviewed on Nov 4, 2025

Super 8 by Wyndham Macon
203 E Briggs Dr, Macon, MO
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $89 total per night from Dec 14 to Dec 15
$89 total
Dec 14 - Dec 15
Total with taxes and fees
This motel features free WiFi in public areas, barbecue grills, and free self parking. Enjoy the free on-the-go breakfast each morning. Staff at the 24-hour ...
The guy checking me in on Monday night was fantastic. Super helpful and friendly! Super clean and comfortable. Incredible deal
Reviewed on Nov 11, 2025

OYO Travelier Motel
201 E Briggs Dr, Macon, MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $75 total per night from Nov 18 to Nov 19
$75 total
Nov 18 - Nov 19
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free parking. Guests will appreciate freebies like continental breakfast and free self ...
Room was great service was awesome
Reviewed on Nov 8, 2025

Americas Best Value Inn & Suites Macon at Sunset Dr
28933 Sunset Drive, Macon, MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $73 total per night from Nov 18 to Nov 19
$73 total
Nov 18 - Nov 19
Total with taxes and fees
A restaurant and a bar/lounge are featured at this motel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self ...
Very clean, comfortable, quiet. I will definitely stay again
Reviewed on Oct 13, 2025

Historic Clark Cabin w/ Deck & Fishing Pond Access
Clark MO
This cottage doesn't skimp on freebies - guests receive free WiFi and free self parking. Barbecue grills are provided for your convenience.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Cairo hotel reviews by fellow wanderers

Super 8 by Wyndham Macon
5 out of 5
Posted 6 days ago
Travelocity Verified Review
"The guy checking me in on Monday night was fantastic. Super helpful and friendly! Super clean and comfortable. Incredible deal"
A verified traveler stayed at Super 8 by Wyndham Macon
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