Book Hotels in Cairo, MO
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Top Cairo hotels

Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness
Cairo MO
This vacation home featured laundry facilities and barbecue grills.
We really enjoyed how this felt like a home away from home. The Christmas decorations, the ambiance, and all the extra effort put in to make our stay wonderful made this a trip to remember. Thank you so much for letting us stay at your beautiful lake house, we’ll be back for sure!
Reviewed on Dec 28, 2025

Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri
Macon MO
This lodge featured laundry facilities and barbecue grills.
Family reunion
The rooms were very clean and comfortable. It was very hot and humid outside, but the AC and ceiling fans kept up well. The host answered questions quickly. We had rain (and lots of it) every day but our last, but had a good time anyway; making use of the game room, large dining areas for other games, ...
Reviewed on Jul 28, 2025

Briggs Convenience Haven, Briggs Convenience Haven
Macon MO
$271 nightly
The price is $271 total per night from Feb 24 to Feb 25
$271 total
Feb 24 - Feb 25
Total with taxes and fees
This vacation home features laundry facilities.
Clean house with very comfortable beds.
Reviewed on Aug 21, 2025

Comfort Inn & Suites Moberly
1801 W Outer Rd Moberly MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Mar 15 to Mar 16
$112 total
Mar 15 - Mar 16
Total with taxes and fees
A gym, free self parking, and free newspapers are featured at this hotel. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. A ...
Friendly front staff and breakfast lady. Room was clean and good sized. Beds were comfortable. I had an enjoyable stay.
Reviewed on Feb 12, 2026

Super 8 by Wyndham Moberly MO
300 E Highway 24 Moberly MO
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $74 total per night from Mar 1 to Mar 2
$74 total
Mar 1 - Mar 2
Total with taxes and fees
Free self parking is available and the motel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
Great friendly staff
Reviewed on Feb 13, 2026

Simple Rewards Inn Shelbina
711 North Highway 15 Shelbina MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $83 total per night from Feb 17 to Feb 18
$83 total
Feb 17 - Feb 18
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
Was a lot nicer than I was expecting
Reviewed on Nov 29, 2025

Super 8 by Wyndham Macon
203 E Briggs Dr Macon MO
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $91 total per night from Feb 23 to Feb 24
$91 total
Feb 23 - Feb 24
Total with taxes and fees
This motel features free WiFi in public areas, barbecue grills, and free self parking. Enjoy the free on-the-go breakfast each morning. Staff at the 24-hour ...
Hotel has improved from previous stays
Reviewed on Dec 31, 2025

OYO Travelier Motel
201 E Briggs Dr Macon MO
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $74 total per night from Mar 7 to Mar 8
$74 total
Mar 7 - Mar 8
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free parking. Guests will appreciate freebies like continental breakfast and free self ...
Yes , staff was courteous and room clean.
Reviewed on Jan 27, 2026

Americas Best Value Inn & Suites Macon at Sunset Dr
28933 Sunset Drive Macon MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $72 total per night from Feb 17 to Feb 18
$72 total
Feb 17 - Feb 18
Total with taxes and fees
A restaurant and a bar/lounge are featured at this motel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self ...
Nice Sunset
Reviewed on Jan 23, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Cairo hotel reviews by fellow wanderers

Comfort Inn & Suites Moberly
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Friendly front staff and breakfast lady. Room was clean and good sized. Beds were comfortable. I had an enjoyable stay. "
A verified traveler from Iowa City stayed at Comfort Inn & Suites Moberly
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