Deals on vacations and trips to Byron

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Byron flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center

2.5 out of 5
Price was $628, price is now $558 per person
$558
per person
Feb 16 - Feb 19
found 15 hours ago
Roundtrip flight included
Chicago (ORD) to Rochester (RST)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like full breakfast and free self parking.
Americas Best Value Inn Zumbrota

Americas Best Value Inn Zumbrota

2 out of 5
Price was $1,255, price is now $1,047 per person
$1,047
per person
Feb 16 - Feb 19
found 15 hours ago
Roundtrip flight included
Chicago (ORD) to Rochester (RST)
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour front desk can provide around-the-clock assistance.
Aspen Select

Aspen Select

3.5 out of 5
Price was $683, price is now $590 per person
$590
per person
Feb 16 - Feb 19
found 15 hours ago
Roundtrip flight included
Chicago (ORD) to Rochester (RST)
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 24-hour business center and free internet in public areas. There's a gym on site, and a 24-hour front desk and a terrace are also provided.
The Berkman

The Berkman

3 out of 5
Folwell
Price was $816, price is now $705 per person
$705
per person
Feb 16 - Feb 19
found 15 hours ago
Roundtrip flight included
Chicago (ORD) to Rochester (RST)
This aparthotel features a gym and a seasonal outdoor pool. Enjoy the a rooftop terrace and perks like free WiFi. Self parking, a 24-hour business center, and a terrace are also offered.
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
Downtown Rochester
Price was $661, price is now $572 per person
$572
per person
Feb 16 - Feb 19
found 15 hours ago
Roundtrip flight included
Chicago (ORD) to Rochester (RST)
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a rooftop terrace on site, and a 24-hour front desk and a snack bar/deli are also provided.

Top Byron hotels deals

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Free Cancellation
Reserve now, pay when you stay
$149 nightly
The price is $172 total per night
$172 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the hot tub, bar/lounge, and laundry facilities.
Pool
Hot Tub
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Free Cancellation
Reserve now, pay when you stay
$155 nightly
The price is $178 total per night
$178 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each morning.
Pool
Breakfast included
Hampton Inn Rochester-South

Hampton Inn Rochester-South

2.5 out of 5
1755 S Broadway Rochester MN
Free Cancellation
Reserve now, pay when you stay
$80 nightly
The price is $93 total per night
$93 total
Jan 24 - Jan 25, 2026
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. You'll appreciate the free area shuttle, 24-hour business center, and free WiFi in public areas.
Pool
Hot Tub
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Free Cancellation
$80 nightly
The price is $92 total per night
$92 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a rooftop terrace on site, and a 24-hour front desk and a snack bar/deli are also provided.
Pet friendly
Free WiFi
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Free Cancellation
Reserve now, pay when you stay
$129 nightly
The price is $149 total per night
$149 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and an area shuttle.
Pool
Hot Tub
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE Rochester MN
Free Cancellation
Reserve now, pay when you stay
$72 nightly
The price is $83 total per night
$83 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the 24-hour business center, express check-out, and conference space. Enjoy the gym and conveniences like a 24-hour front desk and laundry facilities.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Putting Green

Enjoy a round of golf in Byron at Putting Green. Amble around the area's parks or experience its art scene.

Putting Green

Somerby Golf Club

Enjoy a round of golf in Byron at Somerby Golf Club. Amble around the area's parks or experience its art scene.

Somerby Golf Club

East Brookfield Park

After visiting East Brookfield Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

East Brookfield Park

Frequently asked questions

How much are vacation packages to Byron?
$558 is all you need to spend for an exciting vacation in Byron. Bundle your flights and hotel into a Travelocity package and see your savings pile up. With such good prices, you'll want to start packing your suitcase now!
Where can I get the best vacation package deals for Byron?
You can lock in sensational Byron package deals with Travelocity. Mix and match from as many as 400 partner airlines and 1,000,000 worldwide properties and turn those vacation daydreams into a reality.
Why should I purchase my Byron vacation bundle via Travelocity?
Because life is one big journey, and we have everything you need to help you along the way. With our top-notch service and Price Match Guarantee, you can book with confidence. Plus, you can sleep easy while you're away knowing you can reach us with our round-the-clock support.
Can I save on my Byron car rental if I bundle it with my hotel or flight?
You most certainly can — bundle your car, flight and hotel into a Byron vacation package and you can save a tidy sum. With so many things to do in and around Byron, that rental car will come in handy. Once you're behind the wheel, hit the wide open road and cruise toward Mall of America, a famous attraction about 65 mi from Byron.
Which airport is best for Byron?
Heading to Byron means touching down at Rochester Intl. Airport (RST). It's about 11 mi southeast of the downtown area.
What is there to do in Byron?
Click away at the excellent photo opportunities at Oxbow Park, one of the most well-known attractions in Byron. There's so much more to discover in this exciting destination, so give yourself enough time to explore some lesser-known gems.
Where should I stay when visiting Byron?
The 10 Minutes to Mayo Clinic! Duplex in Small Town Byron, MN. is the top choice of many visitors. Book soon to avoid missing out.

Photos of local treasures

Browse Byron vacation photos for more inspiration