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Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 star property
Hotel near Market Arcade Building in Buffalo

Choose dates to view prices

Photo gallery for Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Lobby sitting area
Lobby sitting area
Free daily buffet breakfast
Business center
1 bedroom, in-room safe, desk, laptop workspace

Reviews

8.6 out of 10
Excellent

Popular amenities

  • Free WiFi
  • Air conditioning
  • Gym
  • Business services
  • Laundry

Explore the area

View in a map
601 Main St, Buffalo, NY, 14203
  • Place, Shea's Performing Arts Center
    ‪2 min walk‬
  • Place, Buffalo Niagara Convention Center
    ‪5 min walk‬
  • Place, Niagara Square
    ‪6 min walk‬
  • Airport, Buffalo, NY (BUF-Buffalo Niagara Intl.)
    ‪13 min drive‬

Room options

View all photos for Standard Room

Standard Room | 1 bedroom, in-room safe, desk, laptop workspace

Standard Room

9.2 out of 10
Wonderful
(25 reviews)
  • 500 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom

Suite, 1 Bedroom | 1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom

8.8 out of 10
Excellent
(48 reviews)
  • City view
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed

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About the neighborhood

Buffalo

Downtown Buffalo stay.With a stay at this Downtown Buffalo hotel, you'll be steps from Buffalo Music Hall of Fame and Market Arcade Building. CEPA Gallery and Buffalo Visitor Center are also within half a mile (1 km).

What's nearby

  • Chippewa District - 1 min walk - 0.0 miles
  • Shea's Performing Arts Center - 2 min walk - 0.1 miles
  • Fountain Plaza - 2 min walk - 0.1 miles
  • Buffalo Niagara Convention Center - 5 min walk - 0.3 miles
  • Niagara Square - 6 min walk - 0.4 miles

Getting around

  • Fountain Plaza Station - 1 min walk
  • Buffalo-Exchange Street Station - 18 min walk
  • Buffalo Niagara Intl. Airport (BUF) - 21 min drive

Restaurants

  • ‪Bada Bing - ‬2 min walk
  • ‪Big Ditch Brewing Company - ‬4 min walk
  • ‪Tap House Pub & Grill - ‬4 min walk
  • ‪Lucky Day Whiskey Bar - ‬4 min walk
  • ‪Starbucks - ‬4 min walk

About this property

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Hotel near Market Arcade Building in Buffalo
Public spaces have free WiFi. You'll find a business center on site. Free breakfast is available daily. A fitness center, a vending machine, and laundry facilities are also featured at the business-friendly Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG.

This Buffalo hotel is smoke free.

  • 146 guestrooms or units
  • 7 levels
  • Buffet breakfast (free)
  • Business facilities
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Express check-out
  • Storage area for luggage
  • Front-desk safe
  • Elevator
  • No smoking on site
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers 146 accommodations with safes and coffee/tea makers. Accommodations have separate sitting areas and are furnished with double sofa beds. Cable television is provided. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include shower/tub combinations, complimentary toiletries, and hair dryers.

This Buffalo hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily.

Similar properties

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Wyndham Garden Buffalo Downtown
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  • Free WiFi
  • Restaurant
  • Air conditioning
4.5 out of 5, Wonderful, 1,745 reviews
$132 nightly
The price is $154
Mar 4 - Mar 5
Total with taxes and fees
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Property amenities

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Elevator
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Low-height electrical outlets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

Room amenities

Entertainment

  • 49-inch TV with cable channels

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed, but service animals are welcome

Children and extra beds

  • Children are welcome.
  • Kids stay free! Children 18 years old and younger stay free when using existing bedding.
  • Rollaway/extra beds are not available.
  • Free cribs (infant beds)!

Property payment types

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Nearby parking fee: USD 16.00 per day (500 ft away)

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property uses eco-friendly cleaning products
Safety features at this property include a smoke detector and window guards
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International, and Carte Blanche. Cash is not accepted. This property uses eco-friendly cleaning products.
    For guests' safety, the property includes a smoke detector and window guards in each accommodation. This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

We should mention

  • Children 18 years old and younger stay free in the same room as the parent or guardian when using existing bedding.
  • Registered guests are the only ones allowed to be in guestrooms.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Buffalo Downtown Hotel
Comfort Suites Hotel Downtown
Comfort Suites Downtown Hotel Buffalo
Comfort Suites Downtown Buffalo
Comfort Suites Downtown Buffalo Hotel
Comfort Suites Buffalo
Buffalo Comfort Suites
Holiday Inn Express Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown Medical CTR
Holiday Inn Express Suites Buffalo Downtown Medical CTR by IHG

Frequently asked questions

How close is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG to the airport?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is 10.3 mi (21-min drive) away from the Buffalo Niagara Intl. Airport (BUF) airport, the closest popular airport to the property.

How much does it cost to stay at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

As of Feb 26, 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG on Mar 4, 2026 start from 107.2, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have an airport shuttle?

Airport shuttle services are not available at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offer free breakfast?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers free buffet breakfast every day from 6:00 AM to 10:00 AM.

Is there a casino at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, there is no casino at this hotel, but Seneca Buffalo Creek Casino (3-min drive) and Hamburg Gaming at the Fairgrounds (19-min drive) are nearby.

What time is check-in at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime.

Is there free parking at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Free parking is not available at this hotel.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have a pool?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG does not have a pool.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have a spa?

There are no spa services available at this hotel.

How close is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG to downtown Buffalo?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is 0.4 mi away from Buffalo.

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

Reviews

8.6

Excellent

Rating 10 - Excellent. 568 out of 1017 reviews
Rating 8 - Good. 286 out of 1017 reviews
Rating 6 - Okay. 73 out of 1017 reviews
Rating 4 - Poor. 39 out of 1017 reviews
Rating 2 - Terrible. 51 out of 1017 reviews

9.0/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.6/10

Property conditions & facilities

Reviews

8/10 Good

hector

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Stayed 1 night in Feb 2026

2/10 Terrible

Stephanie

Disliked: Cleanliness, amenities, property conditions & facilities
Very disappointing stay. At check-in, the front desk agent was distracted and unprofessional, carrying on another conversation while helping me. The room keys didn’t work, and I had to go back and forth to the front desk multiple times, waiting in long lines each time. It took about 45 minutes just to get into my room, which made me late when I already had somewhere to be. Once inside, the room clearly wasn’t properly cleaned—there were other guests’ hair products on the floor, a hole in the door, and the toilet wouldn’t flush unless you tried several times. Overall, one of the worst hotel experiences I’ve had. Would not recommend.
Stayed 1 night in Jan 2026

2/10 Terrible

Larry

Disliked: Cleanliness, amenities
Room was not well temperature controlled. Front desk staff was incomplete and their communications resulting in billing issues Amenities wee in transition so no coffee pods available No sign in lobby for washroom to get key from front desk Overall poor with an I don’t care attitude
Stayed 1 night in Oct 2025

10/10 Excellent

Aaron

Liked: Cleanliness, amenities, property conditions & facilities
The front desk clerk. She and her glittering cowboy hat were awesome. The rooms we above average.
Stayed 1 night in Nov 2025

10/10 Excellent

Henry

Traveled with partner
Liked: Cleanliness, staff & service, property conditions & facilities
Mario was awesome! Good area. Easy to get to arena.
Stayed 1 night in Nov 2025

10/10 Excellent

Natalie

Stayed 1 night in Nov 2025

8/10 Good

Ian

Liked: Cleanliness, staff & service
Staff were all excellent - friendly and helpful. The room was great - most comfortable bed I have ever slept in! Only downsides were a limited breakfast (albeit typical in this price bracket) and the noise made by the close-by Buffalo Metro
Stayed 3 nights in Nov 2025

2/10 Terrible

Brian

Traveled with partner
Disliked: Cleanliness
There was a ton of hair in the shower and on the couch, the water took 10 minutes to get luke warm and never got hot, the kcup pods were decaf and tea, no regular coffee, and the deadlock screws were loose and it was almost falling off the door. Called ahead for an early check in, was told "check in will probably be around 2pm" sat in the lobby for an hour no check in till 2:50pm.
Stayed 1 night in Nov 2025

10/10 Excellent

Daron

Liked: Cleanliness, staff & service, amenities
Front desk was amazing
Stayed 1 night in Nov 2025

10/10 Excellent

Ashley

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Oct 2025

10/10 Excellent

Rebecca

Stayed 1 night in Nov 2025

6/10 Okay

Randy

Liked: Staff & service
Room required maintenance, and updating for the price.
Stayed 2 nights in Nov 2025

4/10 Poor

Aziz

Room was noisy.
Stayed 1 night in Oct 2025

2/10 Terrible

Jeffrey

Disliked: Cleanliness, property conditions & facilities
There was no room. This is ridiculous. The hotel claimed that they walked us to another hotel, which was 15 miles away. When we got to that hotel, they apologized and said they told your hotel that they had called them six hours beforehand saying they had no rooms and they couldn’t walk people to their hotel This is absolutely ridiculous considering I’ve already been charged and I’m gonna pay for two hotel rooms that I couldn’t possibly get into Instead of just taking my feedback and discussing it at some meeting, can you please rectify this and give me my money back for Christ sakes
Stayed 1 night in Nov 2025

10/10 Excellent

Teresa

Traveled with family
Liked: Staff & service
The staff, especially B.W. was wonderful and went above and beyond to see to our needs!
Stayed 1 night in Oct 2025

10/10 Excellent

Mary Kramer

Liked: Cleanliness, staff & service, property conditions & facilities
Everyone was phenomenal
Stayed 2 nights in Aug 2025

10/10 Excellent

cheyanne

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Oct 2025

10/10 Excellent

Samuel

Stayed 5 nights in Oct 2025

6/10 Okay

Brad

Staff bey nice, especially BW! Had a
Stayed 2 nights in Oct 2025

10/10 Excellent

Emma

Liked: Cleanliness, staff & service, property conditions & facilities
Staff was warming and friendly!
Stayed 1 night in Oct 2025

6/10 Okay

Donn

Stayed 1 night in Oct 2025

2/10 Terrible

Marco

Stayed 2 nights in Oct 2025

6/10 Okay

Amber

Disliked: Staff & service

Great Stay with the Exception of 1 Front Desk girl

Overall, our stay was good — the hotel itself was clean, comfortable, and well-kept. The breakfast was great, and every staff member we interacted with during our four-day stay was friendly and professional… except for the experience when we first arrived. We got to the hotel about an hour before check-in because we were heading to a football game. The woman behind the front desk told us we’d have to wait the hour, which I understood, but when I asked to use the bathroom to get changed, her attitude was rude and dismissive. She spoke under her breath about me, and when I asked what she said, she got defensive and told me she “wasn’t talking to me.” She also told me they “don’t check bags,” but I could “just leave them there,” which didn’t feel secure or professional. She wasn’t in uniform or wearing a name tag and seemed more like she was hanging out than working. Thankfully, we never saw her again, and everyone else at the hotel was wonderful. Still, that first encounter really set a bad tone for the start of our trip.
Stayed 3 nights in Oct 2025

4/10 Poor

Diana

Business traveler
Nice rooms Did not have breakfast
Stayed 2 nights in Sep 2025

10/10 Excellent

Nicholas

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean and comfortable
Stayed 1 night in Oct 2025