Explore top 2025 5 Star Hotels in Vatican City

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Top Vatican City 5 Star hotels

The Westin Excelsior, Rome

The Westin Excelsior, Rome

5 out of 5
Via Vittorio Veneto 125 Rome RM
Fully refundableReserve now, pay when you stay
$350 nightly
The price is $408 total per night from Dec 23 to Dec 24
$408 total
Dec 23 - Dec 24
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
8.2/10 Very Good! (737 reviews)
Spacious rooms!!!

Reviewed on Nov 19, 2025

Opens in a new windowThe Westin Excelsior, Rome
NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento

5 out of 5
Piazza Dei Cinquecento, 90 Rome RM
Fully refundableReserve now, pay when you stay
$216 nightly
The price is $260 total per night from Dec 21 to Dec 22
$260 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's ...
9/10 Wonderful! (1,000 reviews)
Nice hotel, great location.

Reviewed on Nov 11, 2025

Opens in a new windowNH Collection Roma Palazzo Cinquecento
Sofitel Rome Villa Borghese

Sofitel Rome Villa Borghese

5 out of 5
Via Lombardia 47 Rome RM
Fully refundableReserve now, pay when you stay
$346 nightly
The price is $404 total per night from Dec 14 to Dec 15
$404 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Families will appreciate the onsite laundry facilities, kid-friendly dining, and in-room childcare. ...
9/10 Wonderful! (945 reviews)
Overall 10/10

Reviewed on Aug 27, 2025

Opens in a new windowSofitel Rome Villa Borghese
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

5 out of 5
Piazza Della Repubblica, 47 Rome RM
$606 nightly
The price is $690 total per night from Dec 7 to Dec 8
$690 total
Dec 7 - Dec 8
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in ...
9/10 Wonderful! (997 reviews)
I like the property

Reviewed on Sep 14, 2025

Opens in a new windowAnantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
InterContinental Rome Ambasciatori Palace by IHG

InterContinental Rome Ambasciatori Palace by IHG

5 out of 5
Via V. Veneto 62 Rome RM
Fully refundable
$380 nightly
The price is $441 total per night from Dec 17 to Dec 18
$441 total
Dec 17 - Dec 18
Total with taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the free WiFi in public ...
9.4/10 Exceptional! (154 reviews)
Friendly staff, quick check in and our room was available in the morning

Reviewed on Nov 10, 2025

Opens in a new windowInterContinental Rome Ambasciatori Palace by IHG
W Rome

W Rome

5 out of 5
26/36 Via Liguria Rome RM
Fully refundableReserve now, pay when you stay
$422 nightly
The price is $487 total per night from Dec 15 to Dec 16
$487 total
Dec 15 - Dec 16
Total with taxes and fees
This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Enjoy the 24-hour gym and perks like free WiFi. Enjoy the a rooftop terrace and conveniences ...
9.4/10 Exceptional! (203 reviews)
The staff on arrival and the check-in was very professional and friendly. The room was as usual clean and comfortable. The main restaurant breakfast buffet was first class and the dinner was also very good. The dinner menu needs more options. I had ordered and received four cappuccinos and ALL were ...

Reviewed on Oct 29, 2025

Opens in a new windowW Rome
Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World

5 out of 5
Via Vittorio Veneto 72 Rome RM
Fully refundableReserve now, pay when you stay
$431 nightly
The price is $498 total per night from Dec 15 to Dec 16
$498 total
Dec 15 - Dec 16
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities and in-room ...
8.8/10 Excellent! (490 reviews)
Love our stay for our family of eight. Great staff. Great service. Kid friendly. The rooms are great. We stayed in a suite with two rooms and two bathrooms which is awesome for a big family.

Reviewed on Nov 21, 2025

Opens in a new windowBaglioni Hotel Regina - The Leading Hotels of the World
Radisson Collection Hotel, Roma Antica

Radisson Collection Hotel, Roma Antica

5 out of 5
VIA DELLE BOTTEGHE OSCURE 46 Rome RM
Fully refundableReserve now, pay when you stay
$287 nightly
The price is $339 total per night from Dec 8 to Dec 9
$339 total
Dec 8 - Dec 9
Total with taxes and fees
This smoke-free hotel features 2 restaurants and 2 bars/lounges. Enjoy the a rooftop terrace and perks like free WiFi. Enjoy the steam room and conveniences ...
9.4/10 Exceptional! (143 reviews)
Great hotel and location. Room was perfect for 2 nights in rome. Definitely would stay again.

Reviewed on Nov 21, 2025

Opens in a new windowRadisson Collection Hotel, Roma Antica
Six Senses Rome

Six Senses Rome

5 out of 5
Piazza di San Marcello Rome RM
Fully refundableReserve now, pay when you stay
$1,086 nightly
The price is $1,217 total per night from Dec 6 to Dec 7
$1,217 total
Dec 6 - Dec 7
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Enjoy the a rooftop terrace and perks like free WiFi. You'll appreciate ...
9.4/10 Exceptional! (58 reviews)
Amazing staff, beautifully decorated hotel, super amenities. Truly wonderful find in the heart of Rome.

Reviewed on Nov 17, 2025

Opens in a new windowSix Senses Rome
Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá - The Leading Hotels of the World

5 out of 5
Via del Gianicolo 3 Rome RM
Fully refundableReserve now, pay when you stay
$522 nightly
The price is $597 total per night from Dec 1 to Dec 2
$597 total
Dec 1 - Dec 2
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public ...
9.2/10 Wonderful! (927 reviews)
Staff are really pleasant and accommodating. Especially, Frederick, Andrea and Emma. Staff in the restaurant Follie, Mario and Marco provided exceptional service throughout the evening. Also, staff during breakfast were very friendly.

Reviewed on Nov 26, 2025

Opens in a new windowVilla Agrippina Gran Meliá - The Leading Hotels of the World
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Vatican City Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Vatican City to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Vatican City 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Vatican City before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

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