Explore top 2025 5 Star Hotels in Vatican City

Name: Palazzo Roma - The Leading Hotels of the World
Price range: $741 total
Rating: 9.8

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Top Vatican City 5 Star hotels

Hotel Raphaël – Relais & Châteaux

Largo Febo, 2-Piazza Navona, Rome, RM

$420 nightly

$486 total

Sep 27 - Sep 28

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Families will appreciate the onsite laundry facilities and in-room childcare. WiFi in public areas ...

9/10 Wonderful! (994 reviews)

"Ravello was a great venue off the beaten path. Amazing views."

Reviewed on Sep 21, 2025

The Westin Excelsior, Rome

Via Vittorio Veneto 125, Rome, RM

Fully refundableReserve now, pay when you stay

$532 nightly

$608 total

Sep 28 - Sep 29

Total with taxes and fees

A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

8.2/10 Very Good! (728 reviews)

"Everything was great except for the TV service they have. Tv is old and don’t have smart tv options"

Reviewed on Sep 16, 2025

NH Collection Roma Palazzo Cinquecento

Piazza Dei Cinquecento, 90, Rome, RM

Fully refundableReserve now, pay when you stay

$496 nightly

$570 total

Oct 26 - Oct 27

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's ...

9/10 Wonderful! (1,006 reviews)

"Good location and much more peaceful than the historic centres. Excellent breakfast buffet. Helpful staff."

Reviewed on Sep 12, 2025

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Piazza Della Repubblica, 47, Rome, RM

Fully refundableReserve now, pay when you stay

$873 nightly

$984 total

Oct 26 - Oct 27

Total with taxes and fees

A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in ...

9/10 Wonderful! (1,002 reviews)

"I like the property"

Reviewed on Sep 14, 2025

Sofitel Rome Villa Borghese

Via Lombardia 47, Rome, RM

Fully refundableReserve now, pay when you stay

$677 nightly

$768 total

Oct 25 - Oct 26

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Families will appreciate the onsite laundry facilities, kid-friendly dining, and in-room childcare. ...

9/10 Wonderful! (943 reviews)

"Overall 10/10"

Reviewed on Aug 27, 2025

Radisson Collection Hotel, Roma Antica

VIA DELLE BOTTEGHE OSCURE 46, Rome, RM

Fully refundableReserve now, pay when you stay

$482 nightly

$553 total

Oct 25 - Oct 26

Total with taxes and fees

This smoke-free hotel features 2 restaurants and 2 bars/lounges. Enjoy the a rooftop terrace and perks like free WiFi. Enjoy the steam room and conveniences ...

9.4/10 Exceptional! (120 reviews)

"Everyone is very nice and go the extra mile to please you. I left something in my room and when I came back a week later Federica at the fronk desk handed it to me."

Reviewed on Sep 19, 2025

InterContinental Rome Ambasciatori Palace by IHG

Via V. Veneto 62, Rome, RM

Fully refundable

$635 nightly

$722 total

Oct 26 - Oct 27

Total with taxes and fees

The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the free WiFi in public ...

9.4/10 Exceptional! (146 reviews)

"Great hotel with any incredible services focused staff. I was truly impressed and have stayed at many 5 star hotels during my working life. High recommend."

Reviewed on Sep 5, 2025

W Rome

26/36 Via Liguria, Rome, RM

Fully refundableReserve now, pay when you stay

$559 nightly

$638 total

Oct 26 - Oct 27

Total with taxes and fees

This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Enjoy the 24-hour gym and perks like free WiFi. Enjoy the a rooftop terrace and conveniences ...

9.4/10 Exceptional! (191 reviews)

"Had a very nice stay in Rome here. Service was good and the rooms are clean and nice."

Reviewed on Sep 20, 2025

Grand Hotel Plaza

Via Del Corso 126, Rome, RM

Fully refundableReserve now, pay when you stay

$441 nightly

$509 total

Oct 20 - Oct 21

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. WiFi in public ...

7.2/10 Good! (993 reviews)

Magnificent, beautiful historic hotel!

"I have stayed in this beautiful historic hotel several times over the years. This was my first stay since here since 2016. I was upgraded to a very large suite. The suite was very large, quiet, private and clean. I slept great! The mini bar refrigerator was not cooling (I did not report it until ..."

Reviewed on Sep 21, 2025

Palazzo Roma - The Leading Hotels of the World

Via del Corso 337, 1, Rome, RM

Fully refundableReserve now, pay when you stay

$653 nightly

$741 total

Oct 5 - Oct 6

Total with taxes and fees

A restaurant and a bar/lounge are featured at this property. WiFi in public areas is free. A coffee shop, dry cleaning, and luggage storage are also on ...

9.8/10 Exceptional! (81 reviews)

"Everyone from the staff was super friendly and helpful. Hotel is a boutique hotel, so it is small and gives that warm feeling of “you matter” unlike some other (larger) chains. Beautiful hotel overall. Close to shops, dining, and even the TREVI fountain! Would definitely stay here again."

Reviewed on Aug 31, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vatican City Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Vatican City to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Vatican City 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Vatican City before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Vatican City hotel reviews by fellow wanderers

Hotel 55 Fifty five

5 out of 5

Posted 2 days ago

Travelocity Verified Review

"We were staying in the annex which is about a block away from the main hotel. The annex is on a very busy street close to the Spanish Steps but it was great to sit on the (tiny) balcony and enjoy the lively atmosphere, noise was not a problem. The room was pretty small but looked recently renovated, nicely decorated and very clean. Breakfast was great and served in the annex. The location is fantastic with most of the popular sites very walkable."

A verified traveler stayed at Hotel 55 Fifty five