Explore top 2026 5 Star Hotels in Vatican City

Name: Villa Agrippina Gran Meliá - The Leading Hotels of the World
Price range: $546 total
Rating: 9.2

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Top Vatican City 5 Star hotels

The Westin Excelsior, Rome

Via Vittorio Veneto 125 Rome RM

Fully refundableReserve now, pay when you stay

$548 nightly

$627 total

Jan 31 - Feb 1

Total with taxes and fees

A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

8.2/10 Very Good! (744 reviews)

Very clean, staff was very nice and helpful.

Reviewed on Jan 14, 2026

NH Collection Roma Palazzo Cinquecento

Piazza Dei Cinquecento, 90 Rome RM

Fully refundableReserve now, pay when you stay

$275 nightly

$327 total

Feb 8 - Feb 9

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's ...

9/10 Wonderful! (1,001 reviews)

Comfortable and clean. Love their breakfast. Near Roma Termini station.

Reviewed on Jan 21, 2026

Sofitel Rome Villa Borghese

Via Lombardia 47 Rome RM

Fully refundableReserve now, pay when you stay

$317 nightly

$373 total

Feb 24 - Feb 25

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Families will appreciate the onsite laundry facilities, kid-friendly dining, and in-room childcare. ...

9/10 Wonderful! (949 reviews)

Overall 10/10

Reviewed on Aug 27, 2025

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Piazza Della Repubblica, 47 Rome RM

Fully refundableReserve now, pay when you stay

$665 nightly

$755 total

Jan 29 - Jan 30

Total with taxes and fees

A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in ...

9/10 Wonderful! (998 reviews)

incredible, no hotel compares to it. everything was perfect

Reviewed on Dec 13, 2025

InterContinental Rome Ambasciatori Palace by IHG

Via V. Veneto 62 Rome RM

Fully refundable

$345 nightly

$404 total

Feb 1 - Feb 2

Total with taxes and fees

The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the free WiFi in public ...

9.4/10 Exceptional! (167 reviews)

Enjoyed our stay very much, great location, very clean Very nice room

Reviewed on Jan 17, 2026

W Rome

26/36 Via Liguria Rome RM

Fully refundableReserve now, pay when you stay

$430 nightly

$497 total

Feb 4 - Feb 5

Total with taxes and fees

This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Enjoy the 24-hour gym and perks like free WiFi. Enjoy the a rooftop terrace and conveniences ...

9.4/10 Exceptional! (207 reviews)

Room was clean but it’s kind of dark. It would be nice to have a lamp for extra light as I was in the 1st floor with only a small window. Staff is nice but I was incredibly disappointed that the rooftop was closed for the season. Nothing about the rooftop being seasonal was mentioned on the website. ...

Reviewed on Dec 1, 2025

Baglioni Hotel Regina - The Leading Hotels of the World

Via Vittorio Veneto 72 Rome RM

Fully refundableReserve now, pay when you stay

$394 nightly

$457 total

Jan 29 - Jan 30

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities and in-room ...

8.8/10 Excellent! (507 reviews)

Rooms are clean, breakfast good

Reviewed on Jan 22, 2026

Radisson Collection Hotel, Roma Antica

VIA DELLE BOTTEGHE OSCURE 46 Rome RM

Fully refundableReserve now, pay when you stay

$317 nightly

$373 total

Feb 9 - Feb 10

Total with taxes and fees

This smoke-free hotel features 2 restaurants and 2 bars/lounges. Enjoy the a rooftop terrace and perks like free WiFi. Enjoy the steam room and conveniences ...

9.4/10 Exceptional! (153 reviews)

Staff were exceptionally helpful and courteous. Always ready to make suggestions and offer help. Hotel is centrally located to all of the sights, and many restaurants are nearby. Definitely would recommend this property.

Reviewed on Jan 12, 2026

Six Senses Rome

Piazza di San Marcello Rome RM

Fully refundableReserve now, pay when you stay

$1,257 nightly

$1,406 total

Feb 4 - Feb 5

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Enjoy the a rooftop terrace and perks like free WiFi. You'll appreciate ...

9.6/10 Exceptional! (60 reviews)

This was our first time staying at a Six Senses hotel and we will definitely consider staying at this hotel brand for future travel. The staff were hospitable, kind, and helpful. The food was excellent. The amenities were great.

Reviewed on Dec 26, 2025

Villa Agrippina Gran Meliá - The Leading Hotels of the World

Via del Gianicolo 3 Rome RM

Fully refundableReserve now, pay when you stay

$475 nightly

$546 total

Jan 29 - Jan 30

Total with taxes and fees

A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public ...

9.2/10 Wonderful! (931 reviews)

Excellent services

Reviewed on Jan 13, 2026

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Vatican City Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Vatican City to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Vatican City 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Vatican City before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.