Explore top 2025 5 Star Hotels in Vatican City

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Top Vatican City 5 Star hotels

NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento

5 out of 5
Piazza Dei Cinquecento, 90, Rome, RM
Fully refundableReserve now, pay when you stay
$246 nightly
The price is $294 total per night from Dec 1 to Dec 2
$294 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's ...
9/10 Wonderful! (1,001 reviews)
Excelente

Reviewed on Oct 31, 2025

Opens in a new windowNH Collection Roma Palazzo Cinquecento
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

5 out of 5
Piazza Della Repubblica, 47, Rome, RM
Fully refundableReserve now, pay when you stay
$613 nightly
The price is $698 total per night from Dec 1 to Dec 2
$698 total
Dec 1 - Dec 2
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in ...
9/10 Wonderful! (998 reviews)
I like the property

Reviewed on Sep 14, 2025

Opens in a new windowAnantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
The Westin Excelsior, Rome

The Westin Excelsior, Rome

5 out of 5
Via Vittorio Veneto 125, Rome, RM
Fully refundableReserve now, pay when you stay
$368 nightly
The price is $428 total per night from Nov 29 to Nov 30
$428 total
Nov 29 - Nov 30
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
8.2/10 Very Good! (733 reviews)
Everything was great except for the TV service they have. Tv is old and don’t have smart tv options

Reviewed on Sep 16, 2025

Opens in a new windowThe Westin Excelsior, Rome
Palazzo Montemartini Rome, A Radisson Collection Hotel

Palazzo Montemartini Rome, A Radisson Collection Hotel

5 out of 5
largo giovanni montemartini, 20, Rome, RM
Fully refundableReserve now, pay when you stay
$248 nightly
The price is $296 total per night from Dec 4 to Dec 5
$296 total
Dec 4 - Dec 5
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
8.6/10 Excellent! (706 reviews)
Rented 2 rooms and couldn’t adjust ac in both. One room too cold and one room too hot bc ac didn’t work. Other than that the hotel was clean and pretty. Beds were comfortable. Rooms were spacious. Conveniently located across from train station.

Reviewed on Oct 24, 2025

Opens in a new windowPalazzo Montemartini Rome, A Radisson Collection Hotel
InterContinental Rome Ambasciatori Palace by IHG

InterContinental Rome Ambasciatori Palace by IHG

5 out of 5
Via V. Veneto 62, Rome, RM
Fully refundable
$406 nightly
The price is $470 total per night from Dec 1 to Dec 2
$470 total
Dec 1 - Dec 2
Total with taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the free WiFi in public ...
9.4/10 Exceptional! (151 reviews)
This is a newly renovated property with great materials. Service level is top of the line. Enhanced our Roma trip. Walkable to the main tourist sites.

Reviewed on Oct 11, 2025

Opens in a new windowInterContinental Rome Ambasciatori Palace by IHG
W Rome

W Rome

5 out of 5
26/36 Via Liguria, Rome, RM
Fully refundableReserve now, pay when you stay
$420 nightly
The price is $485 total per night from Nov 23 to Nov 24
$485 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Enjoy the 24-hour gym and perks like free WiFi. Enjoy the a rooftop terrace and conveniences ...
9.4/10 Exceptional! (202 reviews)
The staff on arrival and the check-in was very professional and friendly. The room was as usual clean and comfortable. The main restaurant breakfast buffet was first class and the dinner was also very good. The dinner menu needs more options. I had ordered and received four cappuccinos and ALL were ...

Reviewed on Oct 29, 2025

Opens in a new windowW Rome
Sina Bernini Bristol, Autograph Collection

Sina Bernini Bristol, Autograph Collection

5 out of 5
Piazza Barberini 23, Rome, RM
Fully refundableReserve now, pay when you stay
$351 nightly
The price is $410 total per night from Nov 30 to Dec 1
$410 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
8.2/10 Very Good! (533 reviews)
Amazing staff service and beautiful room

Reviewed on Sep 12, 2025

Opens in a new windowSina Bernini Bristol, Autograph Collection
Palazzo Roma - The Leading Hotels of the World

Palazzo Roma - The Leading Hotels of the World

5 out of 5
Via del Corso 337, 1, Rome, RM
Fully refundableReserve now, pay when you stay
A restaurant and a bar/lounge are featured at this property. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A coffee ...
9.8/10 Exceptional! (94 reviews)
The best of the best. The room is 10/10 the staff is 10/10 the food is 10/10.

Reviewed on Oct 29, 2025

Opens in a new windowPalazzo Roma - The Leading Hotels of the World
Radisson Collection Hotel, Roma Antica

Radisson Collection Hotel, Roma Antica

5 out of 5
VIA DELLE BOTTEGHE OSCURE 46, Rome, RM
Fully refundableReserve now, pay when you stay
$295 nightly
The price is $347 total per night from Nov 23 to Nov 24
$347 total
Nov 23 - Nov 24
Total with taxes and fees
This smoke-free hotel features 2 restaurants and 2 bars/lounges. Enjoy the a rooftop terrace and perks like free WiFi. Enjoy the steam room and conveniences ...
9.4/10 Exceptional! (134 reviews)
Beautiful hotel . Conveniently located to nearby attractions all walking distant. Breakfast was wonderful with amazing staff

Reviewed on Oct 13, 2025

Opens in a new windowRadisson Collection Hotel, Roma Antica
Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World

5 out of 5
Via Vittorio Veneto 72, Rome, RM
Fully refundableReserve now, pay when you stay
$475 nightly
The price is $546 total per night from Dec 3 to Dec 4
$546 total
Dec 3 - Dec 4
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities and in-room ...
8.8/10 Excellent! (483 reviews)
Great location and service staff are top notch. Property and room is a bit tired and time for refresh.

Reviewed on Oct 29, 2025

Opens in a new windowBaglioni Hotel Regina - The Leading Hotels of the World
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Vatican City Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Vatican City to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Vatican City 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Vatican City before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

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