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Top Gulf Coast 5 Star hotels

The Roosevelt New Orleans, A Waldorf Astoria Hotel

The Roosevelt New Orleans, A Waldorf Astoria Hotel

5 out of 5
130 Roosevelt Way New Orleans LA
Fully refundableReserve now, pay when you stay
$201 nightly
The price is $239 total per night from Apr 5 to Apr 6
$239 total
Apr 5 - Apr 6
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (1,000 reviews)
Yes

Reviewed on Mar 22, 2026

Opens in a new windowThe Roosevelt New Orleans, A Waldorf Astoria Hotel
The Henderson Beach Resort & Spa

The Henderson Beach Resort & Spa

5 out of 5
200 Henderson Resort Way Destin FL
$428 nightly
The price is $484 total per night from Apr 15 to Apr 16
$484 total
Apr 15 - Apr 16
Total with taxes and fees
A full-service spa, 4 restaurants, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
9.2/10 Wonderful! (1,002 reviews)
Peaceful beautiful resort.

Reviewed on Mar 24, 2026

Opens in a new windowThe Henderson Beach Resort & Spa
The Tampa EDITION

The Tampa EDITION

5 out of 5
500 Channelside Dr. Tampa FL
Fully refundableReserve now, pay when you stay
$434 nightly
The price is $493 total per night from Apr 6 to Apr 7
$493 total
Apr 6 - Apr 7
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this luxury hotel. Relax with a drink at one of the 4 bars/lounges and get perks like ...
9.4/10 Exceptional! (353 reviews)
Not worth the price

Reviewed on Mar 21, 2026

Opens in a new windowThe Tampa EDITION
The Windsor Court

The Windsor Court

5 out of 5
300 Gravier St New Orleans LA
Fully refundableReserve now, pay when you stay
$360 nightly
The price is $425 total per night from Apr 6 to Apr 7
$425 total
Apr 6 - Apr 7
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
9.8/10 Exceptional! (1,000 reviews)
This was the most luxurious stay ever! We were upgraded to a suite and it was a pleasant surprise! The beds turned down, breakfast in the room, and the absolute best bath soap ever were all excellent. The pillows and mattresses are to die for. The location was perfect and service top notch. Can’t ...

Reviewed on Mar 25, 2026

Opens in a new windowThe Windsor Court
The Post Oak Hotel at Uptown Houston

The Post Oak Hotel at Uptown Houston

5 out of 5
1600 West Loop South Houston TX
Fully refundableReserve now, pay when you stay
$517 nightly
The price is $605 total per night from Apr 16 to Apr 17
$605 total
Apr 16 - Apr 17
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.6/10 Exceptional! (937 reviews)
Great stay!

Reviewed on Mar 21, 2026

Opens in a new windowThe Post Oak Hotel at Uptown Houston
Four Seasons Hotel New Orleans

Four Seasons Hotel New Orleans

5 out of 5
2 Canal Street New Orleans LA
Fully refundableReserve now, pay when you stay
$460 nightly
The price is $543 total per night from Apr 1 to Apr 2
$543 total
Apr 1 - Apr 2
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, laundry ...
9.6/10 Exceptional! (641 reviews)
Love everything about it will be coming back!

Reviewed on Mar 25, 2026

Opens in a new windowFour Seasons Hotel New Orleans
The St. Regis Longboat Key Resort

The St. Regis Longboat Key Resort

5 out of 5
1601 Gulf Of Mexico Drive Longboat Key FL
$1,434 nightly
The price is $1,620 total per night from Apr 6 to Apr 7
$1,620 total
Apr 6 - Apr 7
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and 3 restaurants. There's fun for all ages with a lazy river and a children's club, and supervised ...
9.8/10 Exceptional! (65 reviews)
Everything was amazing!!

Reviewed on Mar 24, 2026

Opens in a new windowThe St. Regis Longboat Key Resort
The Ritz-Carlton, Sarasota

The Ritz-Carlton, Sarasota

5 out of 5
1111 Ritz Carlton Dr Sarasota FL
Fully refundableReserve now, pay when you stay
$857 nightly
The price is $968 total per night from Apr 12 to Apr 13
$968 total
Apr 12 - Apr 13
Total with taxes and fees
This smoke-free hotel features a golf course, a full-service spa, and a marina. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy ...
9.2/10 Wonderful! (1,000 reviews)
Classic Rittz, but could use a few updates so it doesn't start looking like a Marriott.

Reviewed on Mar 4, 2026

Opens in a new windowThe Ritz-Carlton, Sarasota
Four Seasons Hotel Houston

Four Seasons Hotel Houston

5 out of 5
1300 Lamar St Houston TX
Fully refundableReserve now, pay when you stay
$574 nightly
The price is $672 total per night from Apr 7 to Apr 8
$672 total
Apr 7 - Apr 8
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
9.2/10 Wonderful! (1,000 reviews)
I had a strange experience with the bar staff. I reported it to the manager who handled it well. But the Four Seasons no longer has the 5 star service it had when I was younger. They need to address that, retrain, and use spotters to root out those that don't make the cut.

Reviewed on Mar 11, 2026

Opens in a new windowFour Seasons Hotel Houston
Naples Beach Club, A Four Seasons Resort

Naples Beach Club, A Four Seasons Resort

5 out of 5
851 Gulf Shore Blvd N Naples FL
$1,050 nightly
The price is $1,166 total per night from Apr 12 to Apr 13
$1,166 total
Apr 12 - Apr 13
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy beachfront dining and relax with sun loungers and beach ...
Opens in a new windowNaples Beach Club, A Four Seasons Resort
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Gulf Coast Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Gulf Coast to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Gulf Coast 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Gulf Coast before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Gulf Coast hotel reviews by fellow wanderers