Explore top 2026 5 Star Hotels in Cambridge

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Top Cambridge 5 Star hotels

Omni Boston Hotel at the Seaport

Omni Boston Hotel at the Seaport

5 out of 5
450 Summer Street Boston MA
Fully refundableReserve now, pay when you stay
$266 nightly
The price is $309 total per night from Oct 30 to Oct 31
$309 total
Oct 30 - Oct 31
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this luxury hotel. Relax with a drink at one of the 2 bars/lounges and get perks like ...
Opens in a new windowOmni Boston Hotel at the Seaport
Encore Boston Harbor

Encore Boston Harbor

5 out of 5
1 Broadway Everett MA
Fully refundableReserve now, pay when you stay
$314 nightly
The price is $351 total per night from Oct 25 to Oct 26
$351 total
Oct 25 - Oct 26
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and a nightclub. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, ...
9.6/10 Exceptional! (4,225 reviews)
"⭐️⭐️ Very disappointing experience for a 5-star hotel. I stayed at Encore expecting a luxury experience, but unfortunately, that was not what I received. We were woken up around 6:00 AM by protesters yelling and constantly blowing horns, which completely disrupted our stay and our ability to rest. ..."

Reviewed on Sep 28, 2026

Opens in a new windowEncore Boston Harbor
The Langham, Boston

The Langham, Boston

5 out of 5
250 Franklin St Boston MA
Fully refundableReserve now, pay when you stay
$489 nightly
The price is $569 total per night from Oct 30 to Oct 31
$569 total
Oct 30 - Oct 31
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Families will appreciate the onsite laundry facilities, kid-friendly dining, and babysitting. ...
Opens in a new windowThe Langham, Boston
Four Seasons Hotel Boston

Four Seasons Hotel Boston

5 out of 5
200 Boylston St Boston MA
$995 nightly
The price is $1,159 total per night from Oct 30 to Oct 31
$1,159 total
Oct 30 - Oct 31
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
9.4/10 Exceptional! (487 reviews)
"Room was very noisy in the morning and I could not sleep. Work is being done in the building and I was not informed of when arriving from west coast to stay for one night. Staff was very friendly and apologetic."

Reviewed on Sep 25, 2026

Opens in a new windowFour Seasons Hotel Boston
The Charles Hotel

The Charles Hotel

5 out of 5
One Bennett Street Cambridge MA
$336 nightly
The price is $389 total per night from Oct 30 to Oct 31
$389 total
Oct 30 - Oct 31
Total with taxes and fees
A full-service spa, 3 restaurants, and a 24-hour gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
9.4/10 Exceptional! (1,004 reviews)
"Nice"

Reviewed on Sep 25, 2026

Opens in a new windowThe Charles Hotel
Boston Harbor Hotel

Boston Harbor Hotel

5 out of 5
70 Rowes Wharf Boston MA
Fully refundableReserve now, pay when you stay
$629 nightly
The price is $732 total per night from Oct 30 to Oct 31
$732 total
Oct 30 - Oct 31
Total with taxes and fees
A marina, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly dining, ...
Opens in a new windowBoston Harbor Hotel
The Newbury Boston

The Newbury Boston

5 out of 5
15 Arlington St Boston MA
$809 nightly
The price is $942 total per night from Oct 30 to Oct 31
$942 total
Oct 30 - Oct 31
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the picnic area and in-room childcare. If you want to take your pet ...
Opens in a new windowThe Newbury Boston
InterContinental Boston by IHG

InterContinental Boston by IHG

5 out of 5
510 Atlantic Ave Boston MA
$371 nightly
The price is $432 total per night from Oct 30 to Oct 31
$432 total
Oct 30 - Oct 31
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Opens in a new windowInterContinental Boston by IHG
Four Seasons Hotel One Dalton Street, Boston

Four Seasons Hotel One Dalton Street, Boston

5 out of 5
One Dalton Street Boston MA
Fully refundableReserve now, pay when you stay
$745 nightly
The price is $868 total per night from Oct 11 to Oct 12
$868 total
Oct 11 - Oct 12
Total with taxes and fees
A full-service spa, 3 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Opens in a new windowFour Seasons Hotel One Dalton Street, Boston
Mandarin Oriental, Boston

Mandarin Oriental, Boston

5 out of 5
776 Boylston St Boston MA
Fully refundableReserve now, pay when you stay
$756 nightly
The price is $880 total per night from Oct 11 to Oct 12
$880 total
Oct 11 - Oct 12
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate the onsite laundry facilities and babysitting. ...
Opens in a new windowMandarin Oriental, Boston
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Cambridge Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Cambridge to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Cambridge 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Cambridge before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Cambridge hotel reviews by fellow wanderers

Hyatt Regency Boston/Cambridge

Hyatt Regency Boston/Cambridge

5 out of 5
Posted 5 hours ago
Travelocity Verified Review
"Very friendly and helpful staff, they let us check in early and check out later due to the northeastern storms. Very happy with our stay."
A verified traveler stayed at Hyatt Regency Boston/Cambridge
Hyatt Regency Boston/Cambridge