Explore top 2026 4 Star Hotels in Sanford

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Top Sanford 4 Star hotels

JB Duke Hotel

JB Duke Hotel

4 out of 5
230 Science Drive Durham NC
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $226 total per night from Mar 3 to Mar 4
$226 total
Mar 3 - Mar 4
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A business center, ...
9.4/10 Exceptional! (568 reviews)
Everything was good

Reviewed on Feb 18, 2026

Opens in a new windowJB Duke Hotel
21c Museum Hotel Durham

21c Museum Hotel Durham

4 out of 5
111 North Corcoran Street Durham NC
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $187 total per night from Mar 29 to Mar 30
$187 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the sauna and perks like free WiFi. Valet parking, a 24-hour business center, and dry ...
8.4/10 Very Good! (1,004 reviews)
Upon arrival the AC in the room was not working. The room had a musky odor. Our room was next to the elevator so we heard that all night. Our coffee pot did not work, they offered to send someone up but at that point I decided it was not worth wasting my time waiting and went out and bought coffee. ...

Reviewed on Mar 1, 2026

Opens in a new window21c Museum Hotel Durham
DoubleTree Suites by Hilton Raleigh - Durham

DoubleTree Suites by Hilton Raleigh - Durham

4 out of 5
2515 Meridian Pkwy Durham NC
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $109 total per night from Mar 15 to Mar 16
$109 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free WiFi and a free airport shuttle. There's an outdoor ...
9.2/10 Wonderful! (1,002 reviews)
Yes everything excellent. The staff at the desk was amazing

Reviewed on Mar 1, 2026

Opens in a new windowDoubleTree Suites by Hilton Raleigh - Durham
The Durham Hotel

The Durham Hotel

4 out of 5
315 East Chapel Hill Street Durham NC
Fully refundableReserve now, pay when you stay
$186 nightly
The price is $211 total per night from Mar 9 to Mar 10
$211 total
Mar 9 - Mar 10
Total with taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the business center ...
9/10 Wonderful! (659 reviews)
Staff were delightful, room quiet, great location

Reviewed on Mar 1, 2026

Opens in a new windowThe Durham Hotel
DoubleTree by Hilton Raleigh - Cary

DoubleTree by Hilton Raleigh - Cary

4 out of 5
500 Caitboo Avenue Cary NC
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $131 total per night from Mar 29 to Mar 30
$131 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.4/10 Exceptional! (1,001 reviews)
Great room and staff was very attentive.

Reviewed on Feb 27, 2026

Opens in a new windowDoubleTree by Hilton Raleigh - Cary
Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club

4 out of 5
3001 Cameron Blvd Durham NC
Fully refundableReserve now, pay when you stay
$233 nightly
The price is $265 total per night from Mar 8 to Mar 9
$265 total
Mar 8 - Mar 9
Total with taxes and fees
A golf course, 3 restaurants, and an indoor pool are all featured at this boutique hotel. Family-friendly amenities include an arcade/game room and in-room childcare. ...
9.4/10 Exceptional! (1,005 reviews)
The Hotel was Clean. Very well maintained throughout the buildings and grounds. Very friendly and helpful staff. Would definitely stay there again.

Reviewed on Feb 27, 2026

Opens in a new windowWashington Duke Inn & Golf Club
DoubleTree Raleigh Durham Airport at Research Triangle Park

DoubleTree Raleigh Durham Airport at Research Triangle Park

4 out of 5
4810 Page Creek Ln Durham NC
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $129 total per night from Mar 12 to Mar 13
$129 total
Mar 12 - Mar 13
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,001 reviews)
Room and hotel were very clean, employees were friendly. Room was spacious and comfortable.

Reviewed on Feb 21, 2026

Opens in a new windowDoubleTree Raleigh Durham Airport at Research Triangle Park
The Mayton

The Mayton

4 out of 5
301 S Academy St Cary NC
Fully refundableReserve now, pay when you stay
$209 nightly
The price is $237 total per night from Mar 22 to Mar 23
$237 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 3 conference rooms, free WiFi in public areas, ...
9.4/10 Exceptional! (735 reviews)
The staff was very sweet and attentive. The building smelt very well, and our room was very simple and pristine. My wife enjoyed herself very much; it was a great stay-at-home vacation.

Reviewed on Mar 2, 2026

Opens in a new windowThe Mayton
The Carolina Inn, a Destination by Hyatt Hotel

The Carolina Inn, a Destination by Hyatt Hotel

4.5 out of 5
211 Pittsboro Street Chapel Hill NC
Fully refundableReserve now, pay when you stay
$320 nightly
The price is $363 total per night from Mar 14 to Mar 15
$363 total
Mar 14 - Mar 15
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9.6/10 Exceptional! (1,001 reviews)
Consistently a great stat. This is always our hotel of choice when visiting Chapel Hill. Go Heels!

Reviewed on Feb 25, 2026

Opens in a new windowThe Carolina Inn, a Destination by Hyatt Hotel
Graduate by Hilton Chapel Hill

Graduate by Hilton Chapel Hill

4 out of 5
311 W Franklin St Chapel Hill NC
Fully refundableReserve now, pay when you stay
$173 nightly
The price is $196 total per night from Mar 15 to Mar 16
$196 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 2 conference rooms, free WiFi in public areas, ...
9.2/10 Wonderful! (1,000 reviews)
Staff was awesome, clean room, unique features and great location for our stay.

Reviewed on Jan 28, 2026

Opens in a new windowGraduate by Hilton Chapel Hill
Don't see what you're looking for?
See all available properties in Sanford
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Sanford

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Sanford 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Sanford will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Sanford, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Sanford hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity