Explore top 2026 4 Star Hotels in Mediterranean Region

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Top Mediterranean Region 4 Star hotels

Barcelona Airport Hotel

Barcelona Airport Hotel

4 out of 5
Plaza de la Volateria, 3 El Prat de Llobregat
Fully refundableReserve now, pay when you stay
This smoke-free hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (5,163 reviews)
Good spread of breakfast. The front desk staff were helpful and friendly.

Reviewed on Dec 22, 2025

Opens in a new windowBarcelona Airport Hotel
Bettoja Hotel Mediterraneo

Bettoja Hotel Mediterraneo

4 out of 5
Via Cavour 15 Rome RM
Fully refundableReserve now, pay when you stay
This Art Deco hotel features 2 restaurants, a bar/lounge, and a gym. Families will appreciate the onsite laundry facilities and babysitting. Enjoy the a rooftop ...
8.6/10 Excellent! (999 reviews)
The service 100% good. Cleaning very good. The bar perfekt drinks. Breakfast very good with bacon egg and lot of other good thing.

Reviewed on Dec 29, 2025

Opens in a new windowBettoja Hotel Mediterraneo
Hotel Emperador

Hotel Emperador

4 out of 5
Gran Via 53 Madrid Madrid
Fully refundableReserve now, pay when you stay
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
9.2/10 Wonderful! (1,920 reviews)
The room was clean, the hotel staff were attentive and the hotel was centrally located in walking distance from many attractions. I have stayed at this hotel before.

Reviewed on Dec 31, 2025

Opens in a new windowHotel Emperador
Hotel Regina

Hotel Regina

4 out of 5
Alcala 19 Madrid Madrid
Fully refundableReserve now, pay when you stay
$295 nightly
The price is $325 total per night from Jan 25 to Jan 26
$325 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
9.6/10 Exceptional! (2,227 reviews)
Room is clean. Friendly staff. Prefect location to everywhere. Breakfast is very good!! We stayed for 5 nights. We all love this hotel. Definitely will come back again.

Reviewed on Jan 1, 2026

Opens in a new windowHotel Regina
Napoleon Hotel

Napoleon Hotel

4 out of 5
Piazza Vittorio Emanuele II 105 Rome RM
Fully refundableReserve now, pay when you stay
This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. A business center, a coffee shop, and a terrace are also on offer.
8.4/10 Very Good! (1,009 reviews)
Slept well, quiet, lovely to have air con. Tasty and comprehensive breakfast. Excellent value

Reviewed on Dec 31, 2025

Opens in a new windowNapoleon Hotel
Moxy Barcelona

Moxy Barcelona

4 out of 5
Carrer de Mallorca,1-23 Barcelona
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $124 total per night from Jan 7 to Jan 8
$124 total
Jan 7 - Jan 8
Total with taxes and fees
This hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.2/10 Very Good! (461 reviews)
Newly renovated room, very clean. The check in counter is at the 3rd floor right beside the bar with function area where guests can stay and have coffee even after check out. There is a dining option at the roof top of the building. A big grocery store is at the ground floor, next building with hot ...

Reviewed on Dec 16, 2025

Opens in a new windowMoxy Barcelona
Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
$141 nightly
The price is $172 total per night from Jan 11 to Jan 12
$172 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, free WiFi in public areas, and laundry ...
8.6/10 Excellent! (1,919 reviews)
Beautiful historic hotel. Staff was fantastic!

Reviewed on Dec 30, 2025

Opens in a new windowHotel Quirinale
Hotel Liabeny

Hotel Liabeny

4 out of 5
Calle de la Salud 3 Madrid
Fully refundableReserve now, pay when you stay
This hotel features a restaurant, a sauna, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
9.2/10 Wonderful! (1,478 reviews)
The hotel is decent with clean room, good service and breakfast buffet. The garage is a bit tight. The staff is willing to help pull the car out before we left the next day. It's very close to the old town and walking distance to many historic sites.

Reviewed on Dec 26, 2025

Opens in a new windowHotel Liabeny
Hotel Riu Plaza España

Hotel Riu Plaza España

4 out of 5
C/ Gran Via, 84 Madrid
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $211 total per night from Jan 7 to Jan 8
$211 total
Jan 7 - Jan 8
Total with taxes and fees
The hotel's gym, seasonal outdoor pool, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the business center and ...
9.2/10 Wonderful! (4,555 reviews)
Yes

Reviewed on Dec 30, 2025

Opens in a new windowHotel Riu Plaza España
Hotel Chamartin The One

Hotel Chamartin The One

4 out of 5
Agustín de Foxa s/n Madrid Madrid
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $136 total per night from Jan 5 to Jan 6
$136 total
Jan 5 - Jan 6
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee ...
8.6/10 Excellent! (1,010 reviews)
Courteous staff. Let us check in a bit early which was greatly appreciated after 26 hours of travel. Good sized clean room. Great hot water shower!

Reviewed on Dec 31, 2025

Opens in a new windowHotel Chamartin The One
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4 Star Hotels Mediterranean Region

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mediterranean Region 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mediterranean Region will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mediterranean Region, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Mediterranean Region hotel reviews by fellow wanderers