Explore top 2026 4 Star Hotels in Mediterranean Region
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Top Mediterranean Region 4 Star hotels
Barcelona Airport Hotel
Plaza de la Volateria, 3 El Prat de Llobregat
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $185 total per night from Apr 30 to May 1
$185 total
Apr 30 - May 1
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.8/10 Excellent! (5,130 reviews)
We had the 2 bedroom suite. Room was big and clean. Los of space. Hotel is by nothing! You are almost stranded. However, the bar lounge was very nice and the food was good at the restaurant. Breakfast was very good in the morning. It’s about a 15-20 taxi to Barcelona. Staff was good. Only spent 1 ...
Reviewed on Apr 21, 2026
Hotel Quirinale
Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
$277 nightly
The price is $322 total per night from May 17 to May 18
$322 total
May 17 - May 18
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, free WiFi in public areas, and laundry ...
8.6/10 Excellent! (1,940 reviews)
The room was clean and comfortable. The breakfast had an excellent variety of fresh food in a nice setting. The hotel is close to the metro and termini train station. The hotel is within walking distance of historic sites.
Reviewed on Apr 20, 2026
Moxy Barcelona
Carrer de Mallorca,1-23 Barcelona
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $209 total per night from Apr 26 to Apr 27
$209 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.6/10 Excellent! (553 reviews)
Wonderful place to stay . Staff were really friendly and it was very clean . Large hotel but felt very personable. Breakfast was superb so much choice great quality and all you could eat . Small touches like complimentary water every day, all toiletries supplied made a difference . Super room with ...
Reviewed on Apr 20, 2026
Royal Ramblas
La Rambla, 117 Barcelona
Fully refundableReserve now, pay when you stay
$211 nightly
The price is $254 total per night from May 3 to May 4
$254 total
May 3 - May 4
Total with taxes and fees
A restaurant, self parking, and a 24-hour front desk are among this hotel's amenities. WiFi in public areas is free. Express check-out, dry cleaning, and luggage ...
9/10 Wonderful! (1,012 reviews)
Wonderful staff. Decent breakfast.
Reviewed on Apr 20, 2026
Novotel Madrid Center
O'donnell 53 Madrid Madrid
Fully refundableReserve now, pay when you stay
$214 nightly
The price is $236 total per night from May 18 to May 19
$236 total
May 18 - May 19
Total with taxes and fees
This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
9.2/10 Wonderful! (1,157 reviews)
We had a great stay at Novotel Madrid Centre. The location is very convenient, the room was clean, and the staff were all friendly and helpful.
Reviewed on Apr 19, 2026
Hilton Garden Inn Rome Airport
Via Vittorio Bragadin 2 Fiumicino RM
Fully refundableReserve now, pay when you stay
$200 nightly
The price is $232 total per night from May 8 to May 9
$232 total
May 8 - May 9
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
8.2/10 Very Good! (3,792 reviews)
Restaurant was good and had fresh food. Rooms were very clean and restful
Reviewed on Apr 20, 2026
Hotel Regina
Alcala 19 Madrid Madrid
Fully refundableReserve now, pay when you stay
$309 nightly
The price is $340 total per night from Apr 26 to Apr 27
$340 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
9.8/10 Exceptional! (2,298 reviews)
The staff in the restaurant were not very friendly but everything else was great!
Reviewed on Apr 20, 2026
Hotel Riu Plaza España
C/ Gran Via, 84 Madrid
$212 nightly
The price is $234 total per night from May 3 to May 4
$234 total
May 3 - May 4
Total with taxes and fees
The hotel's gym, seasonal outdoor pool, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the business center and ...
9.4/10 Exceptional! (4,778 reviews)
Los empleados amables, la habitación cómoda y limpia. Desayuno no tenía demasiadas opciones en el buffet pero estaba rico.
Reviewed on Apr 20, 2026
The Stanley
1 Odisseos Str. Athens Attiki
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $164 total per night from Apr 29 to Apr 30
$164 total
Apr 29 - Apr 30
Total with taxes and fees
This hotel features 2 restaurants, a bar/lounge, and an outdoor pool. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free WiFi. You'll appreciate ...
8.8/10 Excellent! (2,170 reviews)
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Reviewed on Apr 20, 2026
Hotel Primus Valencia
Calle Menorca 22 Valencia Valencia
$120 nightly
The price is $131 total per night from May 3 to May 4
$131 total
May 3 - May 4
Total with taxes and fees
This smoke-free hotel features a full-service spa, 2 outdoor pools, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi ...
8.8/10 Excellent! (1,060 reviews)
Room was clean, breakfast was good variety. Room was disappointing - very basic, boiling hot despite air con, no coffee machine or useful toiletries such as hair cap. Location was good but would stay nearer old town if went again
Reviewed on Apr 20, 2026
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4 Star Hotels Mediterranean Region
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Mediterranean Region 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Mediterranean Region will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Mediterranean Region, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Mediterranean Region hotel reviews by fellow wanderers
Hilton Rome Airport
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Ok"
A verified traveler stayed at Hilton Rome Airport
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