Explore top 2026 4 Star Hotels in Mediterranean Region

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Top Mediterranean Region 4 Star hotels

Barcelona Airport Hotel

Barcelona Airport Hotel

4 out of 5
Plaza de la Volateria, 3 El Prat de Llobregat
Fully refundableReserve now, pay when you stay
$154 nightly
The price is $174 total per night from Jun 29 to Jun 30
$174 total
Jun 29 - Jun 30
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (5,095 reviews)
"Very nice really clean!"

Reviewed on Jun 7, 2026

Opens in a new windowBarcelona Airport Hotel
Holiday Inn Lisbon by IHG

Holiday Inn Lisbon by IHG

4 out of 5
Avenida Antonio Jose De Almeida 28-A Lisbon
$133 nightly
The price is $150 total per night from Jul 5 to Jul 6
$150 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8.6/10 Excellent! (1,016 reviews)
"Lovely bright reception, bar and restaurant, clearly refurbished very recently. Rooms are more dated but clean and in good condition. Nice staff, good cooked breakfast"

Reviewed on Jun 2, 2026

Opens in a new windowHoliday Inn Lisbon by IHG
Bettoja Hotel Mediterraneo

Bettoja Hotel Mediterraneo

4 out of 5
Via Cavour 15 Rome RM
Fully refundableReserve now, pay when you stay
$210 nightly
The price is $249 total per night from Jun 20 to Jun 21
$249 total
Jun 20 - Jun 21
Total with taxes and fees
This Art Deco hotel features 2 restaurants, a bar/lounge, and a gym. Families will appreciate the onsite laundry facilities and babysitting. Enjoy the a rooftop ...
8.6/10 Excellent! (1,008 reviews)
"It was very good, staff were excellent, room had an outside balcony, centrally located so you can walk to the Colosseum, shopping, great restaurants, train station… it was just a 30 minute drive from the Rome FCU airport"

Reviewed on Jun 7, 2026

Opens in a new windowBettoja Hotel Mediterraneo
The Social Hub Florence Lavagnini

The Social Hub Florence Lavagnini

4 out of 5
Viale Spartaco Lavagnini 70 72 Florence FI
Fully refundableReserve now, pay when you stay
$141 nightly
The price is $171 total per night from Jun 30 to Jul 1
$171 total
Jun 30 - Jul 1
Total with taxes and fees
This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
9/10 Wonderful! (1,397 reviews)
"Too complicated- too problematic check in, too long distances between everything, no ironing facilities in the room."

Reviewed on Jun 7, 2026

Opens in a new windowThe Social Hub Florence Lavagnini
Radisson Blu Hotel

Radisson Blu Hotel

4 out of 5
Avenida Marechal Craveiro Lopes, 390 Lisbon
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $152 total per night from Jun 9 to Jun 10
$152 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. WiFi in public areas is free. Self parking, a business center, and a snack bar/deli are also ...
8.2/10 Very Good! (2,323 reviews)
"Room is outdated. No accessible outlet. We did not have the body wash, had to call for it. The gentleman that checked us in was very helpful and accommodating. I forgot his name. He is very helpful and friendly. Daily free bottle water is great! Location is convenient flying in and out to and from ..."

Reviewed on Jun 6, 2026

Opens in a new windowRadisson Blu Hotel
Hilton Rome Airport

Hilton Rome Airport

4 out of 5
Via Arturo Ferrarin 2 Fiumicino RM
$249 nightly
The price is $286 total per night from Jul 8 to Jul 9
$286 total
Jul 8 - Jul 9
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8.2/10 Very Good! (3,233 reviews)
"The air conditioning was not working very well so we were uncomfortable in the rooms. It was especially distressing because we needed a good night of sleep before an early flight. The staff was kind, but were not able to help us with this issue. I'm sure when the AC is working, its a great hotel ..."

Reviewed on Jun 7, 2026

Opens in a new windowHilton Rome Airport
Hotel Chamartin The One

Hotel Chamartin The One

4 out of 5
Agustín de Foxa s/n Madrid Madrid
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from Jul 5 to Jul 6
$121 total
Jul 5 - Jul 6
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee ...
8.6/10 Excellent! (1,051 reviews)
"The construction happening around the hotel was not ideal but we still got around it."

Reviewed on Jun 7, 2026

Opens in a new windowHotel Chamartin The One
Hilton Garden Inn Rome Airport

Hilton Garden Inn Rome Airport

4 out of 5
Via Vittorio Bragadin 2 Fiumicino RM
$194 nightly
The price is $225 total per night from Jul 8 to Jul 9
$225 total
Jul 8 - Jul 9
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
8.2/10 Very Good! (3,848 reviews)
"This is a convenient spot close to the airport. It has a restaurant, food to go, and laundry room. It doesn’t have a pool or hot tub. The staff was friendly, competent, and helpful."

Reviewed on Jun 7, 2026

Opens in a new windowHilton Garden Inn Rome Airport
Hotel Ripa Roma

Hotel Ripa Roma

4 out of 5
Via Degli Orti Di Trastevere 3 Rome RM
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $164 total per night from Jul 8 to Jul 9
$164 total
Jul 8 - Jul 9
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
8.4/10 Very Good! (1,004 reviews)
"A convenient hotel with large rooms"

Reviewed on Jun 6, 2026

Opens in a new windowHotel Ripa Roma
Hotel Emperador

Hotel Emperador

4 out of 5
Gran Via 53 Madrid Madrid
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $217 total per night from Jun 21 to Jun 22
$217 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
9.2/10 Wonderful! (2,154 reviews)
"Nice hotel, good location, good breakfast."

Reviewed on Jun 7, 2026

Opens in a new windowHotel Emperador
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4 Star Hotels Mediterranean Region

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mediterranean Region 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mediterranean Region will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mediterranean Region, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Mediterranean Region hotel reviews by fellow wanderers