Explore top 2025 4 Star Hotels in Mediterranean Region

Name: The Hoxton Poblenou
Price range: $181 total
Rating: 9

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Top Mediterranean Region 4 Star hotels

Barcelona Airport Hotel

Plaza de la Volateria, 3 El Prat de Llobregat

Fully refundableReserve now, pay when you stay

This smoke-free hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.6/10 Excellent! (5,066 reviews)

Excellent stay

Reviewed on Nov 12, 2025

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Hotel Regina

Alcala 19 Madrid Madrid

Fully refundableReserve now, pay when you stay

$264 nightly

$291 total

Dec 14 - Dec 15

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

9.6/10 Exceptional! (2,194 reviews)

Breakfast

Reviewed on Nov 10, 2025

Napoleon Hotel

Piazza Vittorio Emanuele II 105 Rome RM

$133 nightly

$164 total

Nov 16 - Nov 17

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. A business center, a coffee shop, and a terrace are also on offer.

8.4/10 Very Good! (1,000 reviews)

Staff was so kind!

Reviewed on Nov 12, 2025

Hotel Emperador

Gran Via 53 Madrid Madrid

This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

9.2/10 Wonderful! (1,836 reviews)

Fruits, everything good.

Reviewed on Nov 13, 2025

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Hotel Quirinale

Via Nazionale 7 Rome RM

$139 nightly

$171 total

Dec 14 - Dec 15

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, free WiFi in public areas, and laundry ...

8.6/10 Excellent! (1,908 reviews)

The hotel is great and all the amenities wonderful thank you for the hospitality

Reviewed on Nov 11, 2025

Bettoja Hotel Mediterraneo

Via Cavour 15 Rome RM

Fully refundableReserve now, pay when you stay

This Art Deco hotel features 2 restaurants, a bar/lounge, and a gym. Families will appreciate the onsite laundry facilities and babysitting. Enjoy the a rooftop ...

8.6/10 Excellent! (995 reviews)

Big room, clean and comfortable. Very good location

Reviewed on Nov 5, 2025

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citizenM Rome Isola Tiberina

LUNGOTEVERE DE CENCI 5-8 Rome RM

Fully refundableReserve now, pay when you stay

$161 nightly

$194 total

Nov 30 - Dec 1

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...

9.4/10 Exceptional! (751 reviews)

Cappuccino in the morning and a clean, quiet room. They allowed us an early check in too.

Reviewed on Nov 7, 2025

Hotel Liabeny

Calle de la Salud 3 Madrid

Fully refundableReserve now, pay when you stay

This hotel features a restaurant, a sauna, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...

9.2/10 Wonderful! (1,448 reviews)

Was great

Reviewed on Nov 12, 2025

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Grupotel Mayorazgo

Flor Baja 3 Madrid Madrid

Fully refundableReserve now, pay when you stay

$209 nightly

$230 total

Nov 24 - Nov 25

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Self parking, ...

8.4/10 Very Good! (775 reviews)

Nice stay

Reviewed on Nov 9, 2025

The Hoxton Poblenou

Avinguda Diagonal 205 Barcelona

Fully refundableReserve now, pay when you stay

$151 nightly

$181 total

Dec 6 - Dec 7

Total with taxes and fees

This smoke-free hotel features 2 restaurants, a bar/lounge, and an outdoor pool. Traveling on business? Take advantage of the 7 conference rooms, free WiFi in ...

9/10 Wonderful! (551 reviews)

Overall great experience! The staff were helpful and the facility is really well kept.

Reviewed on Nov 14, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Mediterranean Region

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mediterranean Region 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mediterranean Region will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mediterranean Region, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.