Explore top 2026 4 Star Hotels in Mediterranean Region
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Top Mediterranean Region 4 Star hotels
Barcelona Airport Hotel
Plaza de la Volateria, 3 El Prat de Llobregat
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $193 total per night from Sep 28 to Sep 29
$193 total
Sep 28 - Sep 29
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Hotel101- Madrid
Av. de las Fuerzas Armadas, 328 Madrid
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $87 total per night from Sep 14 to Sep 15
$87 total
Sep 14 - Sep 15
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a poolside bar. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9.4/10 Exceptional! (1,349 reviews)
"Friendly and helpful staff. Brand new building and well designed. Great maintenance as well. It was also unusual that the hotel offered free and unlimited water! highly appreciated!"
Reviewed on Sep 7, 2026
Hotel 3K Barcelona
Rua Laura Alves 10 Lisbon
$114 nightly
The price is $130 total per night from Sep 10 to Sep 11
$130 total
Sep 10 - Sep 11
Total with taxes and fees
A bar/lounge and a 24-hour front desk are featured at this hotel, along with self parking. WiFi in public areas is free. Traveling on business? Take advantage ...
8.4/10 Very Good! (1,005 reviews)
"This was one of the best experiences we’ve ever had! The staff were amazing from the start. They let us keep our luggage at the hotel, the check-in was super smooth and easy and the room was exactly as pictured—great space, comfort and cleanliness. They also helped us out when we made a small mistake ..."
Reviewed on Sep 4, 2026
The Stanley
1 Odisseos Str. Athens Attiki
$148 nightly
The price is $180 total per night from Sep 29 to Sep 30
$180 total
Sep 29 - Sep 30
Total with taxes and fees
This hotel features 2 restaurants, a bar/lounge, and an outdoor pool. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free WiFi. You'll appreciate ...
8.8/10 Excellent! (2,428 reviews)
"Great stay. Friendly and helpful staff. Food was very good. Rooftop views were great"
Reviewed on Sep 7, 2026
Hotel Regina
Alcala 19 Madrid Madrid
Fully refundableReserve now, pay when you stay
$200 nightly
The price is $220 total per night from Sep 9 to Sep 10
$220 total
Sep 9 - Sep 10
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
9.8/10 Exceptional! (2,378 reviews)
"Love Hotel Regina! This is our go to place stay in Madrid."
Reviewed on Sep 5, 2026
Hilton Rome Airport
Via Arturo Ferrarin 2 Fiumicino RM
Fully refundableReserve now, pay when you stay
$331 nightly
The price is $375 total per night from Sep 10 to Sep 11
$375 total
Sep 10 - Sep 11
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8.4/10 Very Good! (3,391 reviews)
"Just a great property properly handle, excellent staff specially a front desk attendant lady Suzanne, very professional yet friendly. Super place !!!!"
Reviewed on Sep 6, 2026
Radisson Blu Hotel
Avenida Marechal Craveiro Lopes, 390 Lisbon
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $156 total per night from Sep 13 to Sep 14
$156 total
Sep 13 - Sep 14
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. WiFi in public areas is free. Self parking, a business center, and a snack bar/deli are also ...
8.2/10 Very Good! (2,462 reviews)
"The hotel is between satisfactory and good. It's at the lower end of what you'd expect from Radisson. The bed was really comfy, and I liked the tea and coffee making facilities in the room. But the cleanliness in public areas (elevators, and breakfast room) was surprisingly bad. Spills weren't cleaned ..."
Reviewed on Sep 5, 2026
Hilton Garden Inn Rome Airport
Via Vittorio Bragadin 2 Fiumicino RM
Fully refundableReserve now, pay when you stay
$223 nightly
The price is $257 total per night from Oct 5 to Oct 6
$257 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
8.2/10 Very Good! (4,023 reviews)
"Clean convenient"
Reviewed on Sep 6, 2026
Holiday Inn Lisbon by IHG
Avenida Antonio Jose De Almeida 28-A Lisbon
Fully refundable
$138 nightly
The price is $156 total per night from Sep 13 to Sep 14
$156 total
Sep 13 - Sep 14
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8.6/10 Excellent! (1,018 reviews)
"Great stay - beds were super comfortable, staff was very helpful. Location was ok. Did not get the breakfast."
Reviewed on Sep 5, 2026
Hotel Gran Versalles
Covarrubias 4 Madrid Madrid
Fully refundableReserve now, pay when you stay
$201 nightly
The price is $221 total per night from Sep 20 to Sep 21
$221 total
Sep 20 - Sep 21
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Self parking, ...
9/10 Wonderful! (1,003 reviews)
"Clean room"
Reviewed on Aug 27, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels Mediterranean Region
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Mediterranean Region 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Mediterranean Region will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Mediterranean Region, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Mediterranean Region hotel reviews by fellow wanderers
Swandor Hotels & Resort Topkapi Palace - All Inclusive
5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"family friendly our 2 year old and 6 year old enjoyed their holiday especially the kids club was amazing. will definitely be coming back. thanks"
A verified traveler stayed at Swandor Hotels & Resort Topkapi Palace - All Inclusive
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