Explore top 2026 4 Star Hotels in Central Missouri

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Top Central Missouri 4 Star hotels

Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

4 out of 5
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from May 24 to May 25
$106 total
May 24 - May 25
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.6/10 Exceptional! (1,437 reviews)
Food staff were excellent. For Breakfast it would be nice to have Bacon on the weekend as an option. Overall Hotel is good My complaint is some of the bed linen was yellowed. Some of the towels were old(yellowed) worn with small holes, fraying, and rough against your skin. I asked for more. One time ...

Reviewed on May 7, 2026

Opens in a new windowDrury Plaza Hotel Columbia East
Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

4 out of 5
315 Four Seasons Dr. Lake Ozark MO
Fully refundableReserve now, pay when you stay
$160 nightly
The price is $175 total per night from May 17 to May 18
$175 total
May 17 - May 18
Total with taxes and fees
This resort features a golf course, a full-service spa, and a marina. Traveling on business? Take advantage of the free WiFi in public areas, conference center, ...
7.4/10 Good! (1,114 reviews)
Great

Reviewed on May 6, 2026

Opens in a new windowLodge Of Four Seasons Golf Resort, Marina & Spa
DoubleTree by Hilton Hotel Jefferson City

DoubleTree by Hilton Hotel Jefferson City

4 out of 5
422 Monroe St Jefferson City MO
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $127 total per night from Jun 2 to Jun 3
$127 total
Jun 2 - Jun 3
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and WiFi in public areas. ...
8.4/10 Very Good! (744 reviews)
Everything was in top shape.

Reviewed on Apr 27, 2026

Opens in a new windowDoubleTree by Hilton Hotel Jefferson City
The Broadway Columbia - a DoubleTree by Hilton

The Broadway Columbia - a DoubleTree by Hilton

4 out of 5
1111 E Broadway Columbia MO
$114 nightly
The price is $129 total per night from May 25 to May 26
$129 total
May 25 - May 26
Total with taxes and fees
This hotel features 2 bars/lounges and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet ...
9.4/10 Exceptional! (1,009 reviews)
Great location. Friendly staff parking is great in a de attached garage. Very convenient. Lots of cute restaurants and bars nearby. Rooftop bar but not able to go due to private parties

Reviewed on May 7, 2026

Opens in a new windowThe Broadway Columbia - a DoubleTree by Hilton
Camden on the Lake Resort & Spa

Camden on the Lake Resort & Spa

4 out of 5
2359 Bittersweet Road Lake Ozark MO
$177 nightly
The price is $189 total per night from May 10 to May 11
$189 total
May 10 - May 11
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas and free ...
9/10 Wonderful! (1,000 reviews)
Loved the front desk lady! Room was beautiful beautiful view loved it

Reviewed on Apr 22, 2026

Opens in a new windowCamden on the Lake Resort & Spa
voco The Tiger Hotel Columbia, MO by IHG

voco The Tiger Hotel Columbia, MO by IHG

4 out of 5
23 S 8th St Columbia MO
Fully refundable
$158 nightly
The price is $179 total per night from May 25 to May 26
$179 total
May 25 - May 26
Total with taxes and fees
A nightclub, 3 restaurants, and a 24-hour gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, ...
9/10 Wonderful! (1,002 reviews)
Beautifully maintained properly with beautiful decorations. Everything was clean and tidy great restaurant choices nearby.

Reviewed on May 4, 2026

Opens in a new windowvoco The Tiger Hotel Columbia, MO by IHG
Boonville Luxury Lodging

Boonville Luxury Lodging

4 out of 5
519 High St Boonville MO
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $187 total per night from May 11 to May 12
$187 total
May 11 - May 12
Total with taxes and fees
This bed & breakfast features free self parking and free WiFi in public areas. Enjoy the free local cuisine breakfast each morning. A garden and a communal living ...
10/10 Exceptional! (45 reviews)
Our B& B host were awesome. Friendly , talkative and very willing to be helpful with any reasonable need. Thank you Linda and Ken for the added touch to our mini-getaway. Breakfast was timely and fantastic. There are soft drinks and bottled water available as needed during our stay and the room treats ...

Reviewed on Apr 28, 2026

Opens in a new windowBoonville Luxury Lodging
Lake View & Boat Slip: Osage Beach Retreat!

Lake View & Boat Slip: Osage Beach Retreat!

4 out of 5
Osage Beach MO
$243 nightly
The price is $257 total per night from May 28 to May 29
$257 total
May 28 - May 29
Total with taxes and fees
A marina and an outdoor pool are featured at this smoke-free apartment. Guests will appreciate free perks like free self parking and WiFi in public areas. Barbecue ...
10/10 Exceptional! (1 review)
Beautiful place! Not hard to find at all! Very nice owners

Reviewed on Apr 7, 2025

Opens in a new windowLake View & Boat Slip: Osage Beach Retreat!
Osage Oasis Unmatched Views, Convenient Location

Osage Oasis Unmatched Views, Convenient Location

4 out of 5
4897 Bridgepoint Dr., Osage Beach, Mo Osage Beach MO
This condo features free WiFi in public areas, a picnic area, and barbecue grills.
8.6/10 Excellent! (4 reviews)
We were not made aware of how many stairs to get to the property. There were liquid plug ins that caused headaches. We tried to air out the place during the day. First night when we closed the vehicle blinds 5 slats were missing which made open spaces in the sliding doors-no privacy. Called management ...

Reviewed on Apr 26, 2026

Opens in a new windowOsage Oasis Unmatched Views, Convenient Location
Osage Beach Condo w/ Private Deck & Lake Views!

Osage Beach Condo w/ Private Deck & Lake Views!

4 out of 5
Osage Beach MO
This apartment doesn't skimp on freebies - guests receive free WiFi and free self parking. An outdoor pool is also provided.
Opens in a new windowOsage Beach Condo w/ Private Deck & Lake Views!
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4 Star Hotels Central Missouri

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Central Missouri 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Central Missouri will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Central Missouri, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Central Missouri hotel reviews by fellow wanderers

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