Cheap American Airlines flights from San Diego to Brussels (SAN to BRU)

Find The Best Day To Fly from San Diego to Brussels

Discover our best American Airlines flight from San Diego SAN to Brussels BRU 

To find the best deals on flights to San Diego from Brussels with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.  

 

Return flights from San Diego SAN to Brussels BRU with American Airlines 

If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from to , it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply. 

 

Book one-way American Airlines flights from San Diego SAN to Brussels BRU 

A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from San Diego to Brussels costs from . Prices and availability subject to change. Additional terms may apply. 

 

The easy way to find cheap flights to Brussels BRU from  San Diego SAN with American Airlines 

To find a cheap American Airlines flight from San Diego SAN to Brussels BRU, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference. 

 

How to find our best airfare deals on American Airlines flights from San Diego SAN to Brussels BRU 

If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as , or if you book a flight with a stopover. 

 

Find nonstop flights from San Diego SAN to Brussels BRU with American Airlines 

If you’re keen to be on Brussels soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it. 

 

Flexible airline tickets for American Airlines flights from San Diego SAN to Brussels BRU 

Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.  

 

There are a lot of reasons to book your flights to Brussels BRU from  San Diego SAN with American Airlines on Travelocity 

At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.

American Airlines Airports
Hop on a(n) American Airlines flight today by flying to many destinations out of these domestic and international airports:
Airport code
Country
Airport name
Number of flights
DFWUSADallas-Fort Worth Intl.599
CLTUSACharlotte-Douglas Intl.536
ORDUSAO'Hare Intl.317
PHLUSAPhiladelphia Intl.247
MIAUSAMiami Intl.193
DCAUSARonald Reagan Washington National152
PHXUSASky Harbor Intl.141
LAXUSALos Angeles Intl.81
LGAUSALaGuardia72
BOSUSALogan Intl.57

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Holiday Inn Express Brussels Airport by IHG

Holiday Inn Express Brussels Airport by IHG

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A restaurant and a bar/lounge are featured at this hotel. Enjoy freebies like buffet breakfast and a roundtrip airport shuttle Self parking, a coffee shop, and ...
8.8/10 Excellent! (317 reviews)
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Reviewed on Aug 13, 2025

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Courtyard by Marriott Brussels

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4.5 out of 5
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This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
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"Excellent condition and a relaxed welcoming environment. Will definitely return and use again."

Reviewed on Aug 12, 2025

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The Liman Hotel

The Liman Hotel

4 out of 5
Rue Royale, 199, Brussels, Brussels
This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. Dry cleaning and luggage storage are also provided.
9.4/10 Exceptional! (212 reviews)
Great hotel
"Our stay was great. The staff was very helping and courteous. The rooms are in great condition. Area is beautiful, safe and easier accessible."

Reviewed on Aug 15, 2025

The Liman Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.