
$90 Cheap American Airlines flights from St. Louis to Detroit (STL to DTW)
Find The Best Day To Fly from St. Louis to Detroit
Amazing American Airlines STL to DTW Flight Deals
The cheapest flights to Detroit Metropolitan Wayne County found within the past 7 days were $121 round trip and $90 one way. Prices and availability subject to change. Additional terms may apply.
DTW From STL Economy Coach Packages on Similar Airlines



Frequently asked questions
Discover our best American Airlines flight from St. Louis STL to Detroit DTW
To find the best deals on flights to St. Louis from Detroit with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from St. Louis STL to Detroit DTW with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $121 to $176, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from St. Louis STL to Detroit DTW
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from St. Louis to Detroit costs from $90. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Detroit DTW from St. Louis STL with American Airlines
To find a cheap American Airlines flight from St. Louis STL to Detroit DTW, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from St. Louis STL to Detroit DTW
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as August, or if you book a flight with a stopover.
Find nonstop flights from St. Louis STL to Detroit DTW with American Airlines
If you’re keen to be on Detroit soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from St. Louis STL to Detroit DTW
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Detroit DTW from St. Louis STL with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to Detroit

Reviewed on Jun 16, 2025

Reviewed on Jun 14, 2025

Reviewed on Jun 12, 2025
Popular American Airlines Flight Routes from STL
- American Airlines STL to FLL
- American Airlines STL to IAD
- American Airlines STL to RDU
- American Airlines STL to PHX
- American Airlines STL to TPA
- American Airlines STL to AVL
- American Airlines STL to LGA
- American Airlines STL to DFW
- American Airlines STL to LAX
- American Airlines STL to MIA
- American Airlines STL to HNL
Top American Airlines Flight Routes from DTW
- American Airlines DTW to FLL
- American Airlines DTW to IAH
- American Airlines DTW to TPA
- American Airlines DTW to JFK
- American Airlines DTW to DFW
- American Airlines DTW to SJU
- American Airlines DTW to MCO
- American Airlines DTW to DEN
- American Airlines DTW to SLC
- American Airlines DTW to LAX
- American Airlines DTW to PHX
Top Flights for American Airlines originating from STL
Domestic
- New York to San Juan (JFK - SJU)
- Chicago to Las Vegas (ORD - LAS)
- Orlando to San Juan (MCO - SJU)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- New York to Santiago (JFK - STI)
- Atlanta to New York (ATL - LGA)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Los Angeles to San Salvador (LAX - SAL)
- Philadelphia to San Juan (PHL - SJU)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
International
- Orlando to San Juan (MCO - SJU)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- New York to San Juan (JFK - SJU)
- New York to Orlando (LGA - MCO)
- Philadelphia to San Juan (PHL - SJU)
- Philadelphia to San Juan (PHL - SJU)
- New York to Santo Domingo (JFK - SDQ)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- San Juan to Orlando (SJU - MCO)
- Chicago to Las Vegas (ORD - LAS)