
$215 Cheap American Airlines flights from Des Moines to Detroit (DSM to DTW)
Find The Best Day To Fly from Des Moines to Detroit
Amazing American Airlines DSM to DTW Flight Deals
The cheapest flights to Detroit Metropolitan Wayne County found within the past 7 days were $257 round trip and $215 one way. Prices and availability subject to change. Additional terms may apply.
DTW From DSM Economy Coach Packages on Similar Airlines


Frequently asked questions
Discover our best American Airlines flight from Des Moines DSM to Detroit DTW
To find the best deals on flights to Des Moines from Detroit with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Des Moines DSM to Detroit DTW with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $257 to $321, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Des Moines DSM to Detroit DTW
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Des Moines to Detroit costs from $215. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Detroit DTW from Des Moines DSM with American Airlines
To find a cheap American Airlines flight from Des Moines DSM to Detroit DTW, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Des Moines DSM to Detroit DTW
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as October, or if you book a flight with a stopover.
Find nonstop flights from Des Moines DSM to Detroit DTW with American Airlines
If you’re keen to be on Detroit soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Des Moines DSM to Detroit DTW
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Detroit DTW from Des Moines DSM with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
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Popular American Airlines Flight Routes from DSM
Top American Airlines Flight Routes from DTW
Domestic
- Atlanta to Las Vegas (ATL - LAS)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- New York to Orlando (JFK - MCO)
- Los Angeles to San Salvador (LAX - SAL)
- New York to Santiago (JFK - STI)
- Chicago to Las Vegas (ORD - LAS)
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Atlanta to Las Vegas (ATL - LAS)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
International
- Los Angeles to San Salvador (LAX - SAL)
- San Juan to Orlando (SJU - MCO)
- Philadelphia to Orlando (PHL - MCO)
- Chicago to Las Vegas (ORD - LAS)
- Philadelphia to San Juan (PHL - SJU)
- San Juan to Orlando (SJU - MCO)
- Boston to Orlando (BOS - MCO)
- New York to Santiago (JFK - STI)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Philadelphia to San Juan (PHL - SJU)
Most Popular
- Grand Rapids to Fort Myers (GRR - RSW)
- Denver to Des Moines (DEN - DSM)
- Grand Rapids to Los Angeles (GRR - LAX)
- Cedar Rapids to Orlando (CID - MCO)
- Des Moines to Seattle (DSM - SEA)
- Cedar Rapids to Dallas (CID - DFW)
- Flint to Orlando (FNT - MCO)
- Grand Rapids to Dallas (GRR - DFW)
- Grand Rapids to Tampa (GRR - TPA)
- Des Moines to Orlando (DSM - MCO)
- Grand Rapids to Phoenix (GRR - PHX)
- Des Moines to Phoenix (DSM - PHX)
- Grand Rapids to Las Vegas (GRR - LAS)
- Delta Grand Rapids (GRR) to Honolulu (HNL) flights
- Grand Rapids to Portland (GRR - PDX)
- Des Moines to Chicago (DSM - ORD)
- Chicago to Des Moines (ORD - DSM)
- Delta Des Moines (DSM) to Las Vegas (LAS) flights
- Grand Rapids to New Orleans (GRR - MSY)
- Phoenix to Des Moines (PHX - DSM)
- Cedar Rapids to Denver (CID - DEN)
- Des Moines to Denver (DSM - DEN)
- Grand Rapids to Orlando (GRR - MCO)
- American Airlines Traverse City (TVC) to Denver (DEN) flights
- United Denver (DEN) to Grand Rapids (GRR) flights
- Des Moines to Dallas (DSM - DFW)
- American Airlines Cedar Rapids (CID) to Phoenix (PHX) flights
- Grand Rapids to Denver (GRR - DEN)
- Grand Rapids to Miami (GRR - MIA)
- Cedar Rapids to Seattle (CID - SEA)