
$139 Cheap American Airlines flights from Des Moines to Orlando (DSM to MCO)
Find The Best Day To Fly from Des Moines to Orlando
Amazing American Airlines DSM to MCO Flight Deals
The cheapest flights to Orlando Intl. found within the past 7 days were $301 round trip and $139 one way. Prices and availability subject to change. Additional terms may apply.
DSM
Des Moines
MCO
Orlando
$301 Roundtrip, found 3 hours ago
$301
Roundtrip
found 3 hours ago
MCO From DSM Economy Coach Packages on Similar Airlines
Price found within the past 48 hours. Click for updated prices.



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Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to Orlando

Cambria Hotel Orlando Airport
7986 CONWAY ROAD, Orlando, FL
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.8/10 Excellent! (1,846 reviews)
"A great value for my 1 night stay in and out of Orlando. Close to the airportt and highways. 👍"
Reviewed on Jun 27, 2025

The View Studio Suites and Event Venue
9309 S Orange Blossom Trail, Orlando, FL
A 24-hour gym is featured at this aparthotel, along with free self parking. Guests will appreciate free perks like cooked-to-order breakfast and WiFi in public ...
8.2/10 Very Good! (1,142 reviews)
"Room very clean"
Reviewed on Jun 25, 2025

DoubleTree by Hilton at the Entrance to Universal Orlando
5780 Major Blvd, Orlando, FL
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. There's fun for all ages with a children's pool and an arcade/game room, and ...
8.2/10 Very Good! (6,302 reviews)
"Loved having a Starbucks!"
Reviewed on Jun 28, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top American Airlines Flight Routes from MCO
Top Flights for American Airlines originating from DSM
Domestic
- New York to Santiago (JFK - STI)
- New York to Orlando (LGA - MCO)
- New York to Orlando (JFK - MCO)
- San Juan to Orlando (SJU - MCO)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- Los Angeles to San Salvador (LAX - SAL)
- Philadelphia to Orlando (PHL - MCO)
- Dallas to Los Angeles (DFW - LAX)
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
International
- Orlando to San Juan (MCO - SJU)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- Philadelphia to Orlando (PHL - MCO)
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
- San Juan to Orlando (SJU - MCO)
- New York to San Juan (JFK - SJU)
- San Juan to Orlando (SJU - MCO)
- Philadelphia to San Juan (PHL - SJU)
- New York to Montego Bay (JFK - MBJ)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
Most Popular
Flights
Atlanta to Miami (ATL - MIA)Philadelphia to Miami (PHL - MIA)JetBlue Airways Boston (BOS) to Orlando (MCO) flightsJetBlue Airways Orlando (MCO) to Las Vegas (LAS) flightsBoston to Miami (BOS - MIA)New York to Fort Lauderdale (JFK - FLL)New York to Tampa (JFK - TPA)Raleigh to Orlando (RDU - MCO)Baltimore to Orlando (BWI - MCO)Chicago to Orlando (ORD - MCO)Los Angeles to Orlando (LAX - MCO)Los Angeles to Miami (LAX - MIA)Minneapolis to Orlando (MSP - MCO)Dallas to Orlando (DFW - MCO)Detroit to Miami (DTW - MIA)Orlando to San Juan (MCO - SJU)JetBlue Airways Boston (BOS) to Fort Lauderdale (FLL) flightsBaltimore to Miami (BWI - MIA)New York to Orlando (JFK - MCO)New York to Miami (JFK - MIA)Hawaiian Airlines Orlando (MCO) to Honolulu (HNL) flightsPhiladelphia to Tampa (PHL - TPA)Philadelphia to Orlando (PHL - MCO)Newark Liberty Intl. Airport to Orlando (EWR - MCO)Orlando to Atlanta (MCO - ATL)Detroit to Orlando (DTW - MCO)Dallas to Miami (DFW - MIA)Hartford to Orlando (BDL - MCO)Cleveland to Orlando (CLE - MCO)Atlanta to Orlando (ATL - MCO)