$294 Cheap American Airlines flights from Lexington to Buffalo (LEX to BUF)
Find The Best Day To Fly from Lexington to Buffalo
Amazing American Airlines LEX to BUF Flight Deals
The cheapest flights to Buffalo Niagara Intl. found within the past 7 days were round trip and $294 one way. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover our best American Airlines flight from Lexington LEX to Buffalo BUF
To find the best deals on flights to Lexington from Buffalo with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Lexington LEX to Buffalo BUF with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from to , it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Lexington LEX to Buffalo BUF
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Lexington to Buffalo costs from $294. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Buffalo BUF from Lexington LEX with American Airlines
To find a cheap American Airlines flight from Lexington LEX to Buffalo BUF, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Lexington LEX to Buffalo BUF
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as , or if you book a flight with a stopover.
Find nonstop flights from Lexington LEX to Buffalo BUF with American Airlines
If you’re keen to be on Buffalo soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Lexington LEX to Buffalo BUF
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Buffalo BUF from Lexington LEX with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
|---|---|---|---|
| DFW | USA | Dallas-Fort Worth Intl. | 599 |
| CLT | USA | Charlotte-Douglas Intl. | 536 |
| ORD | USA | O'Hare Intl. | 317 |
| PHL | USA | Philadelphia Intl. | 247 |
| MIA | USA | Miami Intl. | 193 |
| DCA | USA | Ronald Reagan Washington National | 152 |
| PHX | USA | Sky Harbor Intl. | 141 |
| LAX | USA | Los Angeles Intl. | 81 |
| LGA | USA | LaGuardia | 72 |
| BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to Buffalo
Buffalo Airport Hotel
"Sin comentarios."
Reviewed on Sep 30, 2026
M Hotel Buffalo
"There was there was roaches in my room and they wouldn't give me my money back"
Reviewed on Sep 29, 2026
Sleep Inn & Suites Buffalo Airport
"The hotel itself needs upgrades. The room was really clean and inviting. The beds were comfortable enough for a good night’s sleep. The breakfast was good. The staff were super friendly and especially helpful with restaurant recommendations, etc. since we were visiting and didn’t know the area."
Reviewed on Sep 29, 2026
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