
$165 Cheap American Airlines flights from Miami to Knoxville (MIA to TYS)
Find The Best Day To Fly from Miami to Knoxville
Amazing American Airlines MIA to TYS Flight Deals
The cheapest flights to McGhee Tyson found within the past 7 days were $169 round trip and $165 one way. Prices and availability subject to change. Additional terms may apply.
MIA
Miami
TYS
Knoxville
$169 Roundtrip, found 1 day ago
$169
Roundtrip
found 1 day ago
MIA
Miami
TYS
Knoxville
$239 Roundtrip, found 16 hours ago
$239
Roundtrip
found 16 hours ago
MIA
Miami
TYS
Knoxville
$243 Roundtrip, found 2 days ago
$243
Roundtrip
found 2 days ago
MIA
Miami
TYS
Knoxville
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
MIA
Miami
TYS
Knoxville
$263 Roundtrip, found 5 hours ago
$263
Roundtrip
found 5 hours ago
MIA
Miami
TYS
Knoxville
$265 Roundtrip, found 4 days ago
$265
Roundtrip
found 4 days ago
TYS From MIA Economy Coach Packages on Similar Airlines
Price found within the past 48 hours. Click for updated prices.



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Travelers ❤️ these 🏨 after their flight to Knoxville

Hilton Knoxville Airport
2001 Alcoa Hwy, Alcoa, TN
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,011 reviews)
"Great location to the airport and fantastic staff!"
Reviewed on Jul 15, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
126 Cusick Road, Alcoa, TN
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free ...
8.6/10 Excellent! (1,477 reviews)
"Exactly what we needed for our business trip. Highly recommended ⭐️⭐️⭐️⭐️⭐️"
Reviewed on Jul 14, 2025

Best Western Knoxville Airport/Alcoa
162 Cusick Rd, Alcoa, TN
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
8.4/10 Very Good! (1,014 reviews)
"Very clean"
Reviewed on Jul 16, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular American Airlines Flight Routes from MIA
Top American Airlines Flight Routes from TYS
Top Flights for American Airlines originating from MIA
Domestic
- Boston to Orlando (BOS - MCO)
- Dallas to Las Vegas (DFW - LAS)
- Philadelphia to San Juan (PHL - SJU)
- New York to Santiago (JFK - STI)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Boston to Orlando (BOS - MCO)
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
- Atlanta to Las Vegas (ATL - LAS)
- San Juan to Orlando (SJU - MCO)
- Los Angeles to San Salvador (LAX - SAL)
International
- Philadelphia to San Juan (PHL - SJU)
- Chicago to Las Vegas (ORD - LAS)
- Dallas to Las Vegas (DFW - LAS)
- Philadelphia to San Juan (PHL - SJU)
- Los Angeles to San Salvador (LAX - SAL)
- San Juan to Orlando (SJU - MCO)
- Philadelphia to Orlando (PHL - MCO)
- New York to San Juan (JFK - SJU)
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
- Orlando to San Juan (MCO - SJU)
Most Popular
Flights
- Atlanta to Miami (ATL - MIA)
- Philadelphia to Miami (PHL - MIA)
- JetBlue Airways Boston (BOS) to Orlando (MCO) flights
- JetBlue Airways Orlando (MCO) to Las Vegas (LAS) flights
- Boston to Miami (BOS - MIA)
- JetBlue Airways Boston (BOS) to Nashville (BNA) flights
- New York to Fort Lauderdale (JFK - FLL)
- New York to Tampa (JFK - TPA)
- Raleigh to Orlando (RDU - MCO)
- Baltimore to Orlando (BWI - MCO)
- Chicago to Orlando (ORD - MCO)
- Los Angeles to Orlando (LAX - MCO)
- Los Angeles to Miami (LAX - MIA)
- Minneapolis to Orlando (MSP - MCO)
- Dallas to Orlando (DFW - MCO)
- Orlando to San Juan (MCO - SJU)
- JetBlue Airways Boston (BOS) to Fort Lauderdale (FLL) flights
- Baltimore to Miami (BWI - MIA)
- New York to Orlando (JFK - MCO)
- New York to Miami (JFK - MIA)
- Hawaiian Airlines Orlando (MCO) to Honolulu (HNL) flights
- Philadelphia to Tampa (PHL - TPA)
- Philadelphia to Orlando (PHL - MCO)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Orlando to Atlanta (MCO - ATL)
- Detroit to Orlando (DTW - MCO)
- Dallas to Miami (DFW - MIA)
- Hartford to Orlando (BDL - MCO)
- Cleveland to Orlando (CLE - MCO)
- Atlanta to Orlando (ATL - MCO)