
$236 Cheap American Airlines flights from Milwaukee to Roanoke (MKE to ROA)
Find The Best Day To Fly from Milwaukee to Roanoke
Amazing American Airlines MKE to ROA Flight Deals
The cheapest flights to Roanoke Regional found within the past 7 days were $283 round trip and $236 one way. Prices and availability subject to change. Additional terms may apply.
MKE
Milwaukee
ROA
Roanoke
$283 Roundtrip, found 5 days ago
$283
Roundtrip
found 5 days ago
MKE
Milwaukee
ROA
Roanoke
$303 Roundtrip, found 5 days ago
$303
Roundtrip
found 5 days ago
MKE
Milwaukee
ROA
Roanoke
$308 Roundtrip, found 5 days ago
$308
Roundtrip
found 5 days ago
MKE
Milwaukee
ROA
Roanoke
$345 Roundtrip, found 6 days ago
$345
Roundtrip
found 6 days ago
MKE
Milwaukee
ROA
Roanoke
$354 Roundtrip, found 5 days ago
$354
Roundtrip
found 5 days ago
MKE
Milwaukee
ROA
Roanoke
$360 Roundtrip, found 4 days ago
$360
Roundtrip
found 4 days ago
Frequently asked questions
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to Roanoke

Spark by Hilton Roanoke Airport
3695 Thirlane Rd Nw, Roanoke, VA
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free self parking, and a free airport shuttle. Business travelers can take ...
8.6/10 Excellent! (73 reviews)
"Hotel was very convenient with it's location and price. We have to travel to Roanoke yearly for my child to see a specialist at the hospital and this facility made our trip this year so much easier."
Reviewed on Jul 15, 2025

Hyatt Place Roanoke Airport/Valley View Mall
5040 Valley View Blvd North, Roanoke, VA
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...
8.4/10 Very Good! (1,003 reviews)
"Great stay on our road trip"
Reviewed on Jul 17, 2025

Super 8 by Wyndham Roanoke VA
6616 Thirlane Rd, Roanoke, VA
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
5.2/10 (1,000 reviews)
"Staff was friendly"
Reviewed on Jul 7, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular American Airlines Flight Routes from MKE
Top American Airlines Flight Routes from ROA
Top Flights for American Airlines originating from MKE
Domestic
- Los Angeles to San Salvador (LAX - SAL)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Philadelphia to San Juan (PHL - SJU)
- San Juan to Orlando (SJU - MCO)
- New York to San Juan (JFK - SJU)
- Chicago to Las Vegas (ORD - LAS)
- Los Angeles to Honolulu (LAX - HNL)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- New York to Orlando (JFK - MCO)
- Chicago to Las Vegas (ORD - LAS)
International
- Boston to Orlando (BOS - MCO)
- Orlando to San Juan (MCO - SJU)
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
- Philadelphia to San Juan (PHL - SJU)
- New York to Montego Bay (JFK - MBJ)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- San Juan to Orlando (SJU - MCO)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- New York to Orlando (JFK - MCO)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
Most Popular
Flights
- New York to Norfolk (JFK - ORF)
- Norfolk to New York (ORF - JFK)
- Richmond to Atlanta (RIC - ATL)
- JetBlue Airways Richmond (RIC) to Las Vegas (LAS) flights
- JetBlue Airways Richmond (RIC) to Boston (BOS) flights
- Air India Delhi (DEL) to Chantilly (IAD) flights
- Richmond to Miami (RIC - MIA)
- United Chantilly (IAD) to Las Vegas (LAS) flights
- Washington to Los Angeles (IAD - LAX)
- Norfolk to Miami (ORF - MIA)
- Washington to Orlando (IAD - MCO)
- Los Angeles to Washington (LAX - IAD)
- Air India Chantilly (IAD) to Delhi (DEL) flights
- Norfolk to Orlando (ORF - MCO)
- Dallas to Washington (DFW - IAD)
- Atlanta to Richmond (ATL - RIC)
- Washington to Atlanta (IAD - ATL)
- Denver to Norfolk (DEN - ORF)
- United Chantilly (IAD) to Los Angeles (LAX) flights
- San Francisco to Washington (SFO - IAD)
- Washington to Miami (IAD - MIA)
- Washington to Dallas (IAD - DFW)
- Norfolk to Atlanta (ORF - ATL)
- Boston to Richmond (BOS - RIC)
- Washington to Hyderabad (IAD - HYD)
- Washington to San Diego (IAD - SAN)
- JetBlue Airways Richmond (RIC) to Fort Lauderdale (FLL) flights
- Richmond to Orlando (RIC - MCO)
- Washington to London (IAD - LHR)
- Washington to Barcelona (IAD - BCN)