$236 Cheap American Airlines flights from Milwaukee to Roanoke (MKE to ROA)

Find The Best Day To Fly from Milwaukee to Roanoke

Amazing American Airlines MKE to ROA Flight Deals

The cheapest flights to Roanoke Regional found within the past 7 days were $283 round trip and $236 one way. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Can I catch a flight from General Mitchell Intl. Airport (MKE) to Roanoke Regional Airport (ROA) right now?
For any current Roanoke Regional Airport (ROA) travel advice and quarantine requirements, visit our Covid-19 Travel Advisor. Look before you book your flight, so you don't get caught out en route.
What terminal is American Airlines at Mitchell Intl. Airport?
If you're traveling with American Airlines from General Mitchell Intl. Airport (MKE) to Roanoke Regional Airport (ROA), you might be able to find out the terminal information when you get your boarding pass. If not, contact your airline.
Are there American Airlines non-stop flights from MKE to ROA?
There aren't any nonstop flights with American Airlines from Mitchell Intl. Airport to ROA. You will have at least one stopover, so use the time to stretch your legs before your next flight.
How long is an American Airlines flight from MKE to ROA?
From the moment your American Airlines plane pushes back from the gate at General Mitchell Intl. Airport (MKE) to the moment it pulls into Roanoke Regional Airport (ROA), your trip will take around 3 hours and 24 minutes. With a short flight time like this, it's the perfect spur-of-the-moment vacation.
How many direct and indirect flights does American Airlines fly from MKE to ROA?
You can choose between around 3 flights each day with American Airlines from Mitchell Intl. Airport to Roanoke--Blacksburg Regional Airport.
If I am not able to travel due to COVID-19, can I change my booking to a later date?
For more info about changing your flight to Roanoke Regional Airport (ROA), please visit our Customer Service Portal.
What is the best day to buy a plane ticket?
This just in! Airfares offered on Thursdays tend to be the cheapest, according to flight demand on Travelocity in 2021. Tuesday and Wednesday prices are also good, but you may want to prepare your budget if booking during the weekend, as data shows that is when prices are generally at their highest.
What are the cheapest days to fly?
Frequent travelers may already know this, but earlier in the week can be the cheapest time to fly. In 2021, flights departing on a Monday were generally the cheapest of the week, whereas you may pay a premium for weekend flights when demand is usually high. On average, tickets were most expensive for Saturday departures, so if you need to fly out on a weekend, you might look for deals ahead of time.
How far in advance can you book a flight?
Trying to figure out how early you should book your flight? It's possible to start comparing international airfares on Travelocity up to 12 months in advance. However, it does depend on the carrier as not all airlines release their prices that far out. According to our 2021 flight demand trends, last minute planners can still bag a bargain with some of the cheapest fares appearing 0-2 weeks prior to their travel dates.*According to flight demand on Travelocity.com from January to December 2021. Savings are subject to change based on departure location, date and destination.
American Airlines Airports
Hop on a(n) American Airlines flight today by flying to many destinations out of these domestic and international airports:
Airport code
Country
Airport name
Number of flights
DFWUSADallas-Fort Worth Intl.599
CLTUSACharlotte-Douglas Intl.536
ORDUSAO'Hare Intl.317
PHLUSAPhiladelphia Intl.247
MIAUSAMiami Intl.193
DCAUSARonald Reagan Washington National152
PHXUSASky Harbor Intl.141
LAXUSALos Angeles Intl.81
LGAUSALaGuardia72
BOSUSALogan Intl.57

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2 out of 5
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Reviewed on Jul 15, 2025

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This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...
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Super 8 by Wyndham Roanoke VA

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2 out of 5
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Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
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Super 8 by Wyndham Roanoke VA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.