Cheap Flights to Florence from $255

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How Much Does it Cost To Fly To Florence?

The cheapest prices found with in the last 7 days for return flights were $299 and $255 for one-way flights to Florence for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
EWRFlorenceMarch 3 to March 11$299
EWRFlorenceMarch 3 to March 11$299
MSPFlorenceFebruary 27 to March 2$323
BOSFlorenceFebruary 4 to February 14$329
DFWFlorenceJanuary 21 to January 28$341
DENFlorenceFebruary 3 to February 25$461
TPAFlorenceJanuary 17 to January 25$517
ALBFlorenceJanuary 17 to January 20$554
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
FLLFlorenceJanuary 10 to January 14$540
*Prices include taxes and fees

Florence Flight Information

Traveling to
Florence
Lowest Price
$299
Number of Airlines Serving
Airlines Serving
American Airlines
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Florence Accommodation Deals

Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2 out of 5
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from Jan 11 to Jan 12
$63 total
Jan 11 - Jan 12
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.6/10 (1,001 reviews)
The A/C was a bit difficult to handle. The buttons to change the temperature caused the machine to change between modes settings instead. Not to mention, the room could use some renovating. There was patches of paint just hanging from the ceiling.

Reviewed on Dec 29, 2025

Opens in a new windowRed Roof Inn Florence - Civic Center
Budget Inn Timmonsville

Budget Inn Timmonsville

2 out of 5
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Jan 11 to Jan 12
$68 total
Jan 11 - Jan 12
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (322 reviews)
Clean room, great for price, stayed with spouse, 2 children and two pets. You can hear cars pulling in and out of this location. There was a homeless guy asking for money but you can encounter that anywhere. No bugs, no concerns. :)

Reviewed on Dec 29, 2025

Opens in a new windowBudget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Jan 13 to Jan 14
$74 total
Jan 13 - Jan 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,002 reviews)
Receptionist was very professional and polite. And took her time to answer every question.

Reviewed on Jan 1, 2026

Opens in a new windowDays Inn by Wyndham Florence Near Civic Center
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Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
$101 nightly
The price is $113 total per night from Jan 14 to Jan 15
$113 total
Jan 14 - Jan 15
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (34 reviews)
Good stay, breakfast was the only dis appointment, no hot options. Good price, friendly staff very clean room. Thank you!

Reviewed on Dec 29, 2025

Opens in a new windowSpark by Hilton Florence North I-95, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Florence

The Mantissa Hotel

The Mantissa Hotel

3 out of 5
130 East Carolina Ave Hartsville SC
$149 nightly
The price is $166 total per night from Jan 11 to Jan 12
$166 total
Jan 11 - Jan 12
Total with taxes and fees
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (271 reviews)
Excellent staff and in the heart of a beautiful downtown.

Reviewed on Dec 5, 2025

Opens in a new windowThe Mantissa Hotel
Days Inn by Wyndham Dillon

Days Inn by Wyndham Dillon

2 out of 5
823 Radford Blvd Dillon SC
Stay at this hotel in Dillon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
5.4/10 (871 reviews)
Really enjoyed my stay

Reviewed on Dec 6, 2025

Opens in a new windowDays Inn by Wyndham Dillon
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St Florence SC
$130 nightly
The price is $146 total per night from Jan 18 to Jan 19
$146 total
Jan 18 - Jan 19
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (611 reviews)
Very nice facility; lots of character. Convenient parking. Good breakfast. Very pleasant staff. Would definitely return.

Reviewed on Dec 23, 2025

Opens in a new windowHotel Florence, Tapestry Collection by Hilton
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Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2 out of 5
2111 West Lucas St/I-95 Florence SC
$55 nightly
The price is $62 total per night from Jan 11 to Jan 12
$62 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,006 reviews)
Yes

Reviewed on Jan 3, 2026

Opens in a new windowDays Inn by Wyndham Florence/I-95 North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd Florence SC
$106 nightly
The price is $119 total per night from Feb 8 to Feb 9
$119 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,007 reviews)
We came for a hockey game, which was amazingly right across the street! Beautiful, spacious room at an amazing price. Couldn’t have asked for better accommodations. Thank you!

Reviewed on Dec 30, 2025

Opens in a new windowHome2 Suites by Hilton Florence, SC
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
$101 nightly
The price is $113 total per night from Jan 14 to Jan 15
$113 total
Jan 14 - Jan 15
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (34 reviews)
Good stay, breakfast was the only dis appointment, no hot options. Good price, friendly staff very clean room. Thank you!

Reviewed on Dec 29, 2025

Opens in a new windowSpark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Jan 13 to Jan 14
$74 total
Jan 13 - Jan 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,002 reviews)
Receptionist was very professional and polite. And took her time to answer every question.

Reviewed on Jan 1, 2026

Opens in a new windowDays Inn by Wyndham Florence Near Civic Center
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Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2.5 out of 5
3440 W Radio Dr Florence SC
$110 nightly
The price is $123 total per night from Jan 18 to Jan 19
$123 total
Jan 18 - Jan 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,003 reviews)
Yes

Reviewed on Jan 1, 2026

Opens in a new windowHoliday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Florence Flight and Hotel Packages

Florence flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Motel 6 Florence, SC
Park Inn by Radisson Florence, SC
The Inn at the Crossroads
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Plane Tickets To Florence

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When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Florence to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Florence without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Florence with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Florence today!

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.