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Santa Cruz
Vacations
Top Santa Cruz hotels deals

Ibis Santa Cruz DE LA Sierra
AVENIDA CRISTOBAL DE MENDOZA, Santa Cruz
$40 nightly
The price is $40 total per night
$40 total
Oct 11 - Oct 12
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport shuttle. Free self parking, a coffee shop, and a snack bar/deli are also offered.
Pet friendly
Parking included

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ave. San Martin, #455, Santa Cruz
$122 nightly
The price is $122 total per night
$122 total
Oct 17 - Oct 18
A full-service spa, 2 restaurants, and a hot tub are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Hot Tub

Marriott Santa Cruz de la Sierra Hotel
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
$103 nightly
The price is $103 total per night
$103 total
Oct 4 - Oct 5
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and perks like free self parking.
Pool
Spa

TRYP by Wyndham Santa Cruz
Av. San Martin, Calle 9 Este, no. 4, Equipetrol., Santa Cruz
$87 nightly
The price is $87 total per night
$87 total
Sep 28 - Sep 29
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and free perks like buffet breakfast and free self parking. There's a sauna on site, and a 24-hour front desk and a terrace are also provided.
Pool
Breakfast included

Camino Real Hotel
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
$134 nightly
The price is $134 total per night
$134 total
Oct 1 - Oct 2
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. There's fun for all ages with a children's pool and a waterslide, and babysitting is an added bonus. Unwind with a drink at one of the 2 bars/lounges and enjoy free perks like buffet breakfast and WiFi in public areas.
Pool
Hot Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Plaza 24 de Septiembre
4.5/5(26 reviews)
Learn about the local history of Santa Cruz when you spend time at Plaza 24 de Septiembre. While in the area, you can find time to visit its shops.

San Lorenzo Cathedral
4.5/5(15 reviews)
After visiting San Lorenzo Cathedral, make a plan to see the other sights and activities in Santa Cruz. While in the area, you can find time to visit its shops.
Ventura Mall
4.5/5(28 reviews)
During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area.
Photos of local treasures
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Frequently asked questions
Where to stay in Santa Cruz: Best areas for travelers
- WarnesWarnes: Stay at the Los Jazmines Hotel Resort or the Terramia Resort and you'll be well taken care of. While you'll find a lot of awesome sights here, Warnes Plaza is one thing you can't miss. Make sure it's high on your sightseeing list!
- Samaipata: Plan ahead so you can see all of this bustling destination. Fort Samaipata, Zoologico el refugio and Zoo el Refugio should be at the top of your bucket list. If excellent service and a good night's sleep are your main priorities, the Hotel Casablanca, the Hotel Casablanca Samaipata and the El Pueblito Hotel Boutique are stays to check out.
- San Jose de Chiquitos: Santa Cruz is packed with popular sights, like Church of the Jesuit Mission of St. Joseph. Spend some time exploring this unique attraction before returning to the comfy surrounds of the Hotel Misiones de Chiquitos. Looking for more choices around town? The La Villa Chiquitana is also well-frequented by visitors.
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