Cheap Flights to Santa Cruz from $262

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How Much Does it Cost To Fly To Santa Cruz?

The cheapest prices found with in the last 7 days for return flights were $346 and $262 for one-way flights to Santa Cruz for the period specified. Prices and availability are subject to change. Additional terms apply

Thu, Sep 10 - Sat, Nov 28
BOG
El Dorado Intl.
VVI
Viru Viru Intl.
$483 Roundtrip, found 4 hours ago
$483
Roundtrip
found 4 hours ago
Select LATAM Airlines Group flight, departing Thu, Sep 10 from El Dorado Intl. to Viru Viru Intl., returning Sat, Nov 28, priced at $483 found 4 hours ago
Fri, Feb 19 - Sun, Feb 28
MIA
Miami Intl.
VVI
Viru Viru Intl.
$566 Roundtrip, found 15 hours ago
$566
Roundtrip
found 15 hours ago
Select LATAM Airlines Group flight, departing Fri, Feb 19 from Miami Intl. to Viru Viru Intl., returning Sun, Feb 28, priced at $566 found 15 hours ago
OriginDestinationTravel DatesFlights From*
SCLSanta CruzNovember 7 to November 13$346
MIASanta CruzOctober 23 to November 7$566
MIASanta CruzOctober 23 to November 7$566
BWISanta CruzOctober 23 to November 10$660
BWISanta CruzOctober 23 to November 10$660
PTYSanta CruzSeptember 9 to September 16$692
PTYSanta CruzSeptember 9 to September 16$692
MEXSanta CruzSeptember 17 to September 28$726
MEXSanta CruzSeptember 17 to September 28$726
IADSanta CruzOctober 10 to October 24$738
LAXSanta CruzSeptember 5 to September 19$769
LAXSanta CruzSeptember 5 to September 19$769
IAHSanta CruzSeptember 3 to September 9$901
IAHSanta CruzSeptember 3 to September 9$901
MADSanta CruzOctober 12 to October 13$1,003
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
SCLSanta CruzAugust 29 to September 4$367
SCLSanta CruzAugust 29 to September 4$367
MIASanta CruzAugust 29 to September 11$624
MIASanta CruzAugust 29 to September 11$624
MEXSanta CruzAugust 29 to September 14$745
MEXSanta CruzAugust 29 to September 14$745
IADSanta CruzAugust 29 to September 12$777
IADSanta CruzAugust 29 to September 12$777
IADSanta CruzAugust 29 to September 12$777
*Prices include taxes and fees

Santa Cruz Flight Information

Traveling to
Santa Cruz
Lowest Price
$346
Number of Airlines Serving
Airlines Serving
LATAM Airlines Group, United
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Santa Cruz Accommodation Deals

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455 Santa Cruz
$135 nightly
The price is $135 total per night from Sep 1 to Sep 2
$135 total
Sep 1 - Sep 2
Book a stay at this spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (401 reviews)
"Great breakfast and beautiful property. Would come here again. Felt safe and comfortable."

Reviewed on Aug 16, 2026

Opens in a new windowLos Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Hotel LP Equipetrol

Hotel LP Equipetrol

3.5 out of 5
Dr Victor Pinto, Equipetrol Santa Cruz
$45 nightly
The price is $45 total per night from Aug 28 to Aug 29
$45 total
Aug 28 - Aug 29
Stay at this hotel in Santa Cruz. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Ventura Mall and Santa Cruz Zoo are located ...
8.2/10 Very Good! (210 reviews)
"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"

Reviewed on Jul 14, 2026

Opens in a new windowHotel LP Equipetrol
Yotau All Suites Hotel

Yotau All Suites Hotel

3.5 out of 5
Av. San Martin No. 7 Santa Cruz
Book a stay at this family-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Patio Design LifeStyle Center ...
7/10 Good! (76 reviews)
"My issue was because the property inside the room was old needs a lot maintenance I found a underwear en the cabinet in the bathroom"

Reviewed on Aug 3, 2025

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Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro

3 out of 5
Av.Ejercito Nacional 290 Santa Cruz
$40 nightly
The price is $40 total per night from Sep 26 to Sep 27
$40 total
Sep 26 - Sep 27
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Ramon Tahuichi Aguilera ...
8/10 Very Good! (285 reviews)
"Awesome hotel"

Reviewed on Feb 6, 2026

Opens in a new windowHotel LP Santa Cruz Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top Santa Cruz with Airport Shuttles

Casa Vida

Casa Vida

3.5 out of 5
Condominio Club Campestre Santa Cruz Santa
$95 nightly
The price is $95 total per night from Aug 28 to Aug 29
$95 total
Aug 28 - Aug 29
Book a stay at this family-friendly vacation home in Santa Cruz. Enjoy free WiFi, free parking, and private hot tubs.
9/10 Wonderful! (2 reviews)
"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"

Reviewed on Sep 28, 2017

Opens in a new windowCasa Vida
Sun Hotel

Sun Hotel

3.5 out of 5
Av. Banzer Km 13 Santa Cruz Santa Cruz
$108 nightly
The price is $108 total per night from Aug 28 to Aug 29
$108 total
Aug 28 - Aug 29
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Play Land Amusement Park is ...
8.2/10 Very Good! (398 reviews)
"ten confianza llegando a este hotel, el servicio es espectacular"

Reviewed on Aug 23, 2026

Opens in a new windowSun Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Santa Cruz

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455 Santa Cruz
$135 nightly
The price is $135 total per night from Sep 1 to Sep 2
$135 total
Sep 1 - Sep 2
Book a stay at this spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (401 reviews)
"Great breakfast and beautiful property. Would come here again. Felt safe and comfortable."

Reviewed on Aug 16, 2026

Opens in a new windowLos Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Santa Cruz

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455 Santa Cruz
$135 nightly
The price is $135 total per night from Sep 1 to Sep 2
$135 total
Sep 1 - Sep 2
Book a stay at this spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (401 reviews)
"Great breakfast and beautiful property. Would come here again. Felt safe and comfortable."

Reviewed on Aug 16, 2026

Opens in a new windowLos Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

3.5 out of 5
Calle Las Begonias Nro 45 Santa Cruz
$27 nightly
The price is $27 total per night from Aug 28 to Aug 29
$27 total
Aug 28 - Aug 29
Book a stay at this business-friendly apartment in Santa Cruz. Enjoy free WiFi, free parking, and room service. Popular attractions Patio Design LifeStyle Center ...
8.6/10 Excellent! (104 reviews)
"Good location"

Reviewed on Aug 8, 2026

Opens in a new windowApart Hotel Premium Suites Santa Cruz
Buganvillas Hotel Suites & Spa
Great for families

Buganvillas Hotel Suites & Spa

4 out of 5
Av. Roca y Coronado No. 901 Santa Cruz
Book a stay at this family-friendly hotel in Santa Cruz. Enjoy breakfast (surcharge), room service, and a fitness center. Popular attractions Parque Ecológico ...

Families like: Kids pool, cribs, rollaway beds, outdoor tennis courts

Get rates
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Camino Real Hotel
Great for families

Camino Real Hotel

4.5 out of 5
Av. San Martín y 4to. Anillo Santa Cruz
$145 nightly
The price is $145 total per night from Sep 14 to Sep 15
$145 total
Sep 14 - Sep 15
Book a stay at this luxury hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Centro Cultural ...
Opens in a new windowCamino Real Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Jeep Compass
SUV Jeep Compass

Frequently asked questions

Which airlines fly to Santa Cruz?
10 carriers fly to Santa Cruz, which means you won't be short on choice. Experienced travelers often recommend:

  • BoA
  • Amaszonas
  • Copa Airlines

What airport is best to fly into Santa Cruz?
There's no need to research flight options into different airports when traveling to Santa Cruz. VVI is the city's only airport, and is located 10 mi from the downtown area.
Where to stay in Santa Cruz
Choosing the perfect place to stay is a key ingredient for an unforgettable travel experience. Select from 174 properties in Santa Cruz and start planning the adventure of your dreams!There's no more suitable time to truly spoil yourself than when you're taking a vacation. Lock in a room at the Los Tajibos Hotel And Convention Center and enjoy a taste of the high life during your stay. Traveling with a smaller budget? Don't worry, you won't be left out in the cold. The Casa Internacional Los Aventureros will keep you and your hip-pocket happy.
Places to visit in Santa Cruz
Don't miss the opportunity to explore Plaza 24 de Septiembre, a public square which has helped influence the economic, cultural and social life here. Seeking some more options? You'll enjoy visiting Cine Center to have a break from hectic sightseeing and simply be entertained by a good movie. And that's not all there is. You'll enjoy finding gifts for family and friends, as well as a few well-deserved treats for yourself, at Ventura Mall.
How to get through airport security fast when traveling to Santa Cruz
If you like the idea of spending more time at the airport restaurants and less time wading through security on your way to Santa Cruz, follow these practical tips:

  • Be sure you know the whereabouts of your travel ID and boarding pass. You don't want to hold up the queue when you're asked to hand them over.
  • Bear in mind that belts with metal buckles can set off the body scanner's alarms. If you have one on, you may be instructed to remove it before continuing.
  • Laptops, digital cameras and other electronic devices must be placed in a tub to be X-rayed.
  • Toothpaste, lip balm and other toiletry items in liquid, gel or cream form need to be stored in containers no larger than 3.4 ounces (100 milliliters). They must also fit in a 1-quart (1-liter) clear zip-lock plastic bag.
  • Consider your choice of footwear. Slippers are great because they're a cinch to step out of when you're doing the airport security checks. Try wearing some on your next journey!
  • Some places have stringent biosecurity laws. Consider where you're off to and whether or not it's permissible to fly with fresh fruit.

Plane Tickets To Santa Cruz

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Santa Cruz. Browse through our inventory to explore a wide range of cheap flights to Santa Cruz to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Santa Cruz as you anxiously await to exit the plane and explore what Santa Cruz has to offer. Considering all the amazing local food and culture in Santa Cruz, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Santa Cruz to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Santa Cruz without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Santa Cruz with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Santa Cruz today!

Explore More Ways to Travel with Travelocity

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.