
Cheap Flights to Santa Cruz from $160
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How Much Does it Cost To Fly To Santa Cruz?
The cheapest prices found with in the last 7 days for return flights were $335 and $160 for one-way flights to Santa Cruz for the period specified. Prices and availability are subject to change. Additional terms apply
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| SCL | Santa Cruz | January 21 to January 21 | $395 |
| MIA | Santa Cruz | January 13 to January 20 | $479 |
| MEX | Santa Cruz | January 7 to January 30 | $521 |
| PTY | Santa Cruz | November 25 to November 28 | $555 |
| IAD | Santa Cruz | January 28 to February 18 | $580 |
| IAD | Santa Cruz | January 28 to February 18 | $580 |
| LAX | Santa Cruz | January 13 to February 11 | $706 |
| IAH | Santa Cruz | November 29 to December 5 | $798 |
| MAD | Santa Cruz | January 29 to March 7 | $861 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| SCL | Santa Cruz | November 21 to November 29 | $462 |
| IAD | Santa Cruz | November 23 to January 30 | $625 |
| IAD | Santa Cruz | November 23 to January 30 | $625 |
| MIA | Santa Cruz | November 22 to November 24 | $675 |
| IAH | Santa Cruz | November 23 to November 28 | $1,055 |
| MAD | Santa Cruz | November 21 to November 24 | $1,150 |
| LAX | Santa Cruz | November 21 to November 29 | $1,273 |
Santa Cruz Flight Information
Traveling to | Santa Cruz |
|---|---|
Lowest Price | $335 |
Number of Airlines Serving | |
Airlines Serving | Boliviana De Aviacion, avianca |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Santa Cruz Accommodation Deals

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Functional room with direct access to the pool.
Reviewed on Oct 22, 2025

Hotel LP Equipetrol
So, the mattress and pillows were not that comfortable, hard. No microwave and the sheets not the size of the bed, smaller. The treatment from the hotel personnel was good.
Reviewed on Feb 21, 2025

Yotau All Suites Hotel
My issue was because the property inside the room was old needs a lot maintenance I found a underwear en the cabinet in the bathroom
Reviewed on Aug 3, 2025

Hotel LP Santa Cruz Centro
Clean, friendly staff
Reviewed on Jun 2, 2024
Our Top Santa Cruz with Airport Shuttles

Casa Vida
buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa
Reviewed on Sep 28, 2017

Sun Hotel
I had arranged airport shuttle for our late arrival. When we came out with our bags there was an unmanned counter for Sun Hotel that had a sign with our name. We were instructed to call the number and the van arrived in 5 minutes. I was expecting to be greeted by someone, but this worked. It is so ...
Reviewed on Nov 9, 2025
Luxury Hotels in Santa Cruz

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Functional room with direct access to the pool.
Reviewed on Oct 22, 2025
Family Friendly Hotels in Santa Cruz

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Functional room with direct access to the pool.
Reviewed on Oct 22, 2025

Apart Hotel Premium Suites Santa Cruz
Everything is perfect!!
Reviewed on Oct 29, 2025

Buganvillas Hotel Suites & Spa
Families like: Kids pool, cribs, rollaway beds, outdoor tennis courts
Extremely satisfy with the service that this resort provided to us. Definitely will return back. Follow me on YouTube #TeamWithERVING
Reviewed on Aug 14, 2021

Camino Real Hotel
Families like: Kids pool, waterslide, playground, babysitting
The parrots. Unique
Reviewed on Oct 25, 2025
Need a Car For After Your Flight?
Economy

Compact

Midsize

SUV

Plane Tickets To Santa Cruz
Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Santa Cruz. Browse through our inventory to explore a wide range of cheap flights to Santa Cruz to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Santa Cruz as you anxiously await to exit the plane and explore what Santa Cruz has to offer. Considering all the amazing local food and culture in Santa Cruz, we won't hold this against you.
When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Santa Cruz to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Santa Cruz without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Santa Cruz with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Santa Cruz today!
Explore More Ways to Travel with Travelocity
- Hotels near Viru Viru Intl.
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- Colinas del Urubo Hotels
- Resorts in Colinas del Urubo
- All Inclusive Resorts & in Santa Cruz
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- Hotels with Free Breakfast in Santa Cruz
- Hotels with Waterslides in Santa Cruz
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- Flights from Viru Viru Intl.
- Aeroflot-Russian Airlines Moscow (SVO) to Santa Cruz (VVI) flights
- Air Europa Barcelona (BCN) to Santa Cruz (VVI) flights
- Amaszonas Asuncion (ASU) to Santa Cruz (VVI) flights
- American Airlines Austin (AUS) to Santa Cruz (VVI) flights
- American Airlines Charlotte (CLT) to Santa Cruz (VVI) flights
- American Airlines Dallas (DFW) to Santa Cruz (VVI) flights
- American Airlines Los Angeles (LAX) to Santa Cruz (VVI) flights
- American Airlines Miami (MIA) to Santa Cruz (VVI) flights
- American Airlines Philadelphia (PHL) to Santa Cruz (VVI) flights
- American Airlines Reno (RNO) to Santa Cruz (VVI) flights
- Avianca Lima (LIM) to Santa Cruz (VVI) flights
- Avianca Orlando (MCO) to Santa Cruz (VVI) flights
- Avianca Portland (PDX) to Santa Cruz (VVI) flights
- Avianca San Francisco (SFO) to Santa Cruz (VVI) flights
- Avianca Washington (IAD) to Santa Cruz (VVI) flights
- Boliviana De Aviacion La Paz (LPB) to Santa Cruz (VVI) flights
- Boliviana De Aviacion São Paulo (GRU) to Santa Cruz (VVI) flights
- Boliviana De Aviacion Miami (MIA) to Santa Cruz (VVI) flights
- British Airways London (LHR) to Santa Cruz (VVI) flights
- Copa Las Vegas (LAS) to Santa Cruz (VVI) flights
- Copa Lincoln (LNK) to Santa Cruz (VVI) flights
- Copa Los Angeles (LAX) to Santa Cruz (VVI) flights
- Copa Montreal (YUL) to Santa Cruz (VVI) flights
- Copa San Diego (SAN) to Santa Cruz (VVI) flights
- Copa Phoenix (PHX) to Santa Cruz (VVI) flights
- Copa Tampa (TPA) to Santa Cruz (VVI) flights
- Copa Panama City (PTY) to Santa Cruz (VVI) flights
- Copa Washington (IAD) to Santa Cruz (VVI) flights
- Delta Atlanta (ATL) to Santa Cruz (VVI) flights
- Delta New York (JFK) to Santa Cruz (VVI) flights
- Emirates Dubai (DXB) to Santa Cruz (VVI) flights
- Iberia Dakar (DSS) to Santa Cruz (VVI) flights
- Klm Amsterdam (AMS) to Santa Cruz (VVI) flights
- Latam Airlines Group Santiago (SCL) to Santa Cruz (VVI) flights
- Latam Airlines Group São Paulo (GRU) to Santa Cruz (VVI) flights
- Latam Airlines Group Lima (LIM) to Santa Cruz (VVI) flights
- Latam Airlines Group Miami (MIA) to Santa Cruz (VVI) flights
- United Addis Ababa (ADD) to Santa Cruz (VVI) flights
- United Denver (DEN) to Santa Cruz (VVI) flights
- United Houston (IAH) to Santa Cruz (VVI) flights
- United St. Louis (STL) to Santa Cruz (VVI) flights
- United Newark Liberty Intl. Airport (EWR) to Santa Cruz (VVI) flights
- United Sacramento (SMF) to Santa Cruz (VVI) flights
- United Seattle (SEA) to Santa Cruz (VVI) flights
- Flights from Atlanta (ATL) to Santa Cruz (VVI)
- Flights from Austin (AUS) to Santa Cruz (VVI)
- Flights from Boston (BOS) to Santa Cruz (VVI)
- Flights from Baltimore (BWI) to Santa Cruz (VVI)
- Flights from Cochabamba (CBB) to Santa Cruz (VVI)
- Flights from Charlotte (CLT) to Santa Cruz (VVI)
- Flights from Columbus (CMH) to Santa Cruz (VVI)
- Flights from Washington (DCA) to Santa Cruz (VVI)
- Flights from Denver (DEN) to Santa Cruz (VVI)
- Flights from Dallas (DFW) to Santa Cruz (VVI)
- Flights from Douala (DLA) to Santa Cruz (VVI)
- Flights from Newark Liberty Intl. Airport (EWR) to Santa Cruz (VVI)
- Flights from Grand Rapids (GRR) to Santa Cruz (VVI)
- Flights from São Paulo (GRU) to Santa Cruz (VVI)
- Flights from Washington (IAD) to Santa Cruz (VVI)
- Flights from Houston (IAH) to Santa Cruz (VVI)
- Flights from New York (JFK) to Santa Cruz (VVI)
- Flights from Las Vegas (LAS) to Santa Cruz (VVI)
- Flights from Los Angeles (LAX) to Santa Cruz (VVI)
- Flights from La Paz (LPB) to Santa Cruz (VVI)
- Flights from Orlando (MCO) to Santa Cruz (VVI)
- Flights from Miami (MIA) to Santa Cruz (VVI)
- Flights from Minneapolis (MSP) to Santa Cruz (VVI)
- Flights from Nairobi (NBO) to Santa Cruz (VVI)
- Flights from Chicago (ORD) to Santa Cruz (VVI)
- Flights from Portland (PDX) to Santa Cruz (VVI)
- Flights from Phoenix (PHX) to Santa Cruz (VVI)
- Flights from Panama City (PTY) to Santa Cruz (VVI)
- Flights from Raleigh (RDU) to Santa Cruz (VVI)
- Flights from Richmond (RIC) to Santa Cruz (VVI)
- Flights from Seattle (SEA) to Santa Cruz (VVI)
- Flights from San Francisco (SFO) to Santa Cruz (VVI)
- Flights from Salt Lake City (SLC) to Santa Cruz (VVI)
- Flights from Orange County (SNA) to Santa Cruz (VVI)
- Flights from Argyle (SVD) to Santa Cruz (VVI)
- Flights from Uyuni (UYU) to Santa Cruz (VVI)
- Flights from Comayagua (XPL) to Santa Cruz (VVI)
- Flights from El Trompillo
- Flights from Albuquerque (ABQ) to Santa Cruz (SRZ)
- Flights from Columbia (CAE) to Santa Cruz (SRZ)
- Flights from Charlotte (CLT) to Santa Cruz (SRZ)
- Flights from Oakland (OAK) to Santa Cruz (SRZ)
- Flights from Orange County (SNA) to Santa Cruz (SRZ)

