Cheap Flights to Santa Cruz from $149

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How Much Does it Cost To Fly To Santa Cruz?

The cheapest prices found with in the last 7 days for return flights were $293 and $149 for one-way flights to Santa Cruz for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
SCLSanta CruzJuly 10 to August 16$413
MIASanta CruzJuly 29 to August 12$526
MEXSanta CruzAugust 12 to August 20$549
IADSanta CruzSeptember 8 to September 18$587
IADSanta CruzSeptember 8 to September 18$587
PTYSanta CruzOctober 7 to October 14$593
LAXSanta CruzAugust 16 to August 25$685
IAHSanta CruzJuly 21 to August 1$797
MADSanta CruzSeptember 28 to October 28$1,091
FCOSanta CruzJuly 27 to July 28$1,756
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
SCLSanta CruzJuly 6 to July 16$592
MIASanta CruzJuly 5 to August 5$696
IADSanta CruzJuly 5 to July 10$715
IADSanta CruzJuly 5 to July 10$715
IAHSanta CruzJuly 6 to July 10$814
LAXSanta CruzJuly 6 to July 13$996
MADSanta CruzJuly 6 to July 21$1,361
*Prices include taxes and fees

Santa Cruz Flight Information

Traveling to
Santa Cruz
Lowest Price
$293
Number of Airlines Serving
Airlines Serving
Boliviana De Aviacion, avianca, Paranair
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Santa Cruz Accommodation Deals

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455, Santa Cruz
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (318 reviews)
"Always an amazing hotel"

Reviewed on Jun 21, 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Hotel LP Equipetrol

Hotel LP Equipetrol

3.5 out of 5
Dr Victor Pinto, Equipetrol, esquina Marcelo Terceros Banzer, Santa Cruz
Stay at this 3.5-star hotel in Santa Cruz. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Ventura Mall and Santa Cruz Zoo are ...
8/10 Very Good! (198 reviews)
"So, the mattress and pillows were not that comfortable, hard. No microwave and the sheets not the size of the bed, smaller. The treatment from the hotel personnel was good."

Reviewed on Feb 21, 2025

Hotel LP Equipetrol
Yotau All Suites Hotel

Yotau All Suites Hotel

3.5 out of 5
Av. San Martin No. 7, Santa Cruz
Stay at this 3.5-star family-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Patio Design LifeStyle Center ...
"I like everything"

Reviewed on Apr 19, 2023

Yotau All Suites Hotel
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Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro

3 out of 5
Av.Ejercito Nacional 290, (frente Stadium Tahuichi), Santa Cruz
Stay at this 3-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Ramon Tahuichi Aguilera ...
7.8/10 Good! (280 reviews)
"Clean, friendly staff"

Reviewed on Jun 2, 2024

Hotel LP Santa Cruz Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top Santa Cruz with Airport Shuttles

Casa Vida

Casa Vida

3.5 out of 5
Condominio Club Campestre, Kilometro 13 doble via La Guardia, Santa Cruz, Santa
Stay at this 3.5-star family-friendly vacation home in Santa Cruz. Enjoy free WiFi, free parking, and private hot tubs.
"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"

Reviewed on Sep 28, 2017

Casa Vida
Sun Hotel

Sun Hotel

3.5 out of 5
Av. Banzer Km 13, Aeropuerto Internacional Viru Viru, Santa Cruz, Santa Cruz
Stay at this 3.5-star business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Play Land Amusement Park is ...
8.2/10 Very Good! (300 reviews)
"The airport shuttle driver was waiting for me when I came out from baggage claim. Room was nice and cool. I enjoyed the breakfast"

Reviewed on May 13, 2025

Sun Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Santa Cruz

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455, Santa Cruz
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (318 reviews)
"Always an amazing hotel"

Reviewed on Jun 21, 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Santa Cruz

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455, Santa Cruz
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (318 reviews)
"Always an amazing hotel"

Reviewed on Jun 21, 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

3.5 out of 5
Calle Las Begonias Nro 45, a 1 cuadra de la Av. San Martin, Santa Cruz
Stay at this 3.5-star business-friendly aparthotel in Santa Cruz. Enjoy free WiFi, free parking, and room service. Popular attractions Patio Design LifeStyle ...
8.4/10 Very Good! (88 reviews)
"The personal was very helpful and they answered very quickly"

Reviewed on May 11, 2025

Apart Hotel Premium Suites Santa Cruz
Buganvillas Hotel Suites & Spa
Great for families

Buganvillas Hotel Suites & Spa

4 out of 5
Av. Roca y Coronado No. 901, Santa Cruz
Stay at this 4-star family-friendly hotel in Santa Cruz. Enjoy breakfast (surcharge), room service, and a fitness center. Popular attractions Parque Ecológico ...
7.4/10 Good! (92 reviews)

Families like: Kids pool, cribs, rollaway beds, outdoor tennis courts

Travelers say...
"Extremely satisfy with the service that this resort provided to us. Definitely will return back. Follow me on YouTube #TeamWithERVING"

Reviewed on Aug 14, 2021

Buganvillas Hotel Suites & Spa
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Camino Real Hotel
Great for families

Camino Real Hotel

4.5 out of 5
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
Stay at this 4.5-star luxury hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Santa Cruz ...
8.8/10 Excellent! (386 reviews)

Families like: Kids pool, waterslide, playground, babysitting

Travelers say...
"Great Hotel, had a great time ."

Reviewed on Jun 2, 2025

Camino Real Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Frequently asked questions

Which airlines fly to Santa Cruz?
10 carriers fly to Santa Cruz, which means you won't be short on choice. Experienced travelers often recommend:

  • BoA
  • Amaszonas
  • Copa Airlines

What airport is best to fly into Santa Cruz?
There's no need to research flight options into different airports when traveling to Santa Cruz. VVI is the city's only airport, and is located 10 mi from the downtown area.
Where to stay in Santa Cruz
Choosing the perfect place to stay is a key ingredient for an unforgettable travel experience. Select from 174 properties in Santa Cruz and start planning the adventure of your dreams!There's no more suitable time to truly spoil yourself than when you're taking a vacation. Lock in a room at the Los Tajibos Hotel And Convention Center and enjoy a taste of the high life during your stay. Traveling with a smaller budget? Don't worry, you won't be left out in the cold. The Casa Internacional Los Aventureros will keep you and your hip-pocket happy.
Places to visit in Santa Cruz
Don't miss the opportunity to explore Plaza 24 de Septiembre, a public square which has helped influence the economic, cultural and social life here. Seeking some more options? You'll enjoy visiting Cine Center to have a break from hectic sightseeing and simply be entertained by a good movie. And that's not all there is. You'll enjoy finding gifts for family and friends, as well as a few well-deserved treats for yourself, at Ventura Mall.
How to get through airport security fast when traveling to Santa Cruz
If you like the idea of spending more time at the airport restaurants and less time wading through security on your way to Santa Cruz, follow these practical tips:

  • Be sure you know the whereabouts of your travel ID and boarding pass. You don't want to hold up the queue when you're asked to hand them over.
  • Bear in mind that belts with metal buckles can set off the body scanner's alarms. If you have one on, you may be instructed to remove it before continuing.
  • Laptops, digital cameras and other electronic devices must be placed in a tub to be X-rayed.
  • Toothpaste, lip balm and other toiletry items in liquid, gel or cream form need to be stored in containers no larger than 3.4 ounces (100 milliliters). They must also fit in a 1-quart (1-liter) clear zip-lock plastic bag.
  • Consider your choice of footwear. Slippers are great because they're a cinch to step out of when you're doing the airport security checks. Try wearing some on your next journey!
  • Some places have stringent biosecurity laws. Consider where you're off to and whether or not it's permissible to fly with fresh fruit.

Plane Tickets To Santa Cruz

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Santa Cruz. Browse through our inventory to explore a wide range of cheap flights to Santa Cruz to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Santa Cruz as you anxiously await to exit the plane and explore what Santa Cruz has to offer. Considering all the amazing local food and culture in Santa Cruz, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Santa Cruz to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Santa Cruz without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Santa Cruz with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Santa Cruz today!

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.