Explore 1 Luxury Hotels in Santa Cruz

Name: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Price range: $131 total
Rating: 8.8

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Best Luxury Hotels in Santa Cruz

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Ave. San Martin, #455, Santa Cruz

$131 nightly

$131 total

Dec 8 - Dec 9

A full-service spa, 2 restaurants, and a hot tub are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and ...

8.8/10 Excellent! (337 reviews)

Functional room with direct access to the pool.

Reviewed on Oct 22, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5 star hotels in Santa Cruz

Novotel Santa Cruz De La Sierra

AV ROCA CORONADO 901, ENTRE TERCER Y CUARTO ANILLO, Santa Cruz

$89 nightly

$89 total

Dec 1 - Dec 2

9/10 Wonderful! (103 reviews)

Santa Cruz Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Santa Cruz luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Santa Cruz to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Santa Cruz will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Santa Cruz, and plan your next opulent escape.